Nature Search

Ter, a Function which generates the Ends of the Mature λ Chromosome

S. MOUSSET
R. THOMAS
Research18 Jan 1969
Nature

Volume: 221, P: 242-244
Tailoring the pH dependence of enzyme catalysis using protein engineering

Paul G. Thomas
Alan J. Russell
Alan R. Fersht
Research28 Nov 1985
Nature

Volume: 318, P: 375-376
Mapping of polyomavirus middle T domain that is responsible for AP-1 activation

Maria Leonor S Oliveira
Thomas M Roberts
Mari CS Armelin
Research16 Jun 1998
Oncogene

Volume: 16, P: 2975-2982
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor

There is a need for effective antiviral drugs against RSV infection. Conducting an RSV repurposing screen using the ReFRAME library Sake et al. identify lonafarnib as an RSV fusion protein inhibitor, characterize its binding site within the viral protein and show its antiviral effects in a mouse model.

Svenja M. Sake
Xiaoyu Zhang
Thomas Pietschmann
ResearchOpen Access08 Feb 2024
Nature Communications

Volume: 15, P: 1-15
Identification of specific binding proteins for a nuclear location sequence

Stephen A. Adam
Thomas J. Lobl
Larry Gerace
Research19 Jan 1989
Nature

Volume: 337, P: 276-279
Nuclear quantum effects enter the mainstream

The approximation underlying most atomistic simulations to treat nuclei classically can lead to large errors and the failure to capture important physical effects. This Review reports on recent developments that enable modelling of quantum nuclei at a computational cost comparable with that of a classical simulation.

Thomas E. Markland
Michele Ceriotti
Reviews28 Feb 2018
Nature Reviews Chemistry

Volume: 2, P: 1-14
Quantum fluctuations can promote or inhibit glass formation

Intuition suggests that the occurrence of large quantum fluctuations should prevent a material from forming a glass by enabling its atoms to rearrange into a lower-energy ordered state. But new simulations suggest the opposite could be true, with fluctuations sometimes enhancing glass formation.

Thomas E. Markland
Joseph A. Morrone
David R. Reichman
Research09 Jan 2011
Nature Physics

Volume: 7, P: 134-137
A two-directional vibrational probe reveals different electric field orientations in solution and an enzyme active site

Preorganized electric fields may be essential for the extraordinary catalytic power of enzymes. Now, it has been demonstrated how electric field strengths can be monitored along two directions using a vibrational Stark probe, enabling the observation of distinct electric field orientations in an enzyme active site compared with those in simple solvents.

Chu Zheng
Yuezhi Mao
Steven G. Boxer
Research05 May 2022
Nature Chemistry

Volume: 14, P: 891-897
Direct observation of ultrafast hydrogen bond strengthening in liquid water

Liquid ultrafast electron scattering measures structural responses in liquid water with femtosecond temporal and atomic spatial resolution to reveal a transient hydrogen bond contraction then thermalization preceding relaxation of the OH stretch.

Jie Yang
Riccardo Dettori
Xijie Wang
Research25 Aug 2021
Nature

Volume: 596, P: 531-535
On the exact continuous mapping of fermions

Andrés Montoya-Castillo
Thomas E. Markland
ResearchOpen Access28 Aug 2018
Scientific Reports

Volume: 8, P: 1-9
SPICE, A Dataset of Drug-like Molecules and Peptides for Training Machine Learning Potentials

Peter Eastman
Pavan Kumar Behara
Thomas E. Markland
ResearchOpen Access04 Jan 2023
Scientific Data

Volume: 10, P: 1-11

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