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A crucial requirement for Hedgehog signaling in small cell lung cancer

The authors find that cell-intrinsic activation of Hedgehog signaling without genetic alterations is a contributing feature to the progression and chemotherapy resistance of small-cell lung carcinoma, and that Hedgehog inhibition can prevent lung cancer growth and recurrence.

Kwon-Sik Park
Luciano G Martelotto
Julien Sage
Research09 Oct 2011
Nature Medicine

Volume: 17, P: 1504-1508
Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease

Alzheimer’s disease has been associated with increased structural brain aging. Here the authors describe a model that predicts brain aging from resting state functional connectivity data, and demonstrate this is accelerated in individuals with pre-clinical familial Alzheimer’s disease.

Julie Gonneaud
Alex T. Baria
Etienne Vachon-Presseau
ResearchOpen Access09 Sept 2021
Nature Communications

Volume: 12, P: 1-17
Differences in the Effects in the Newborn Piglet of Various Nonsteroidal Antiinflammatory Drugs on Cerebral Blood Flow but Not on Cerebrovascular Prostaglandins

Sylvain Chemtob
Kae Beharry
Jacob V Aranda
Research01 Jul 1991
Pediatric Research

Volume: 30, P: 106-111
Vasopressin and Catecholamine Secretion during Metabolic Acidemia in the Ovine Fetus

Daniel J Faucher
Thomas W Lowe
Charles R Rosenfeld
Research01 Jan 1987
Pediatric Research

Volume: 21, P: 38-43
Engagement and attrition in digital mental health: current challenges and potential solutions

Katharine A. Smith
Thomas Ward
Andrea Cipriani
ResearchOpen Access02 Jul 2025
npj Digital Medicine

Volume: 8, P: 1-9
Abnormal Adrenal Steroidogenesis in Growth-Retarded Newborn Infants

C Richard Parker JR
E Stephen Buchina
Thomas K Barefoot
Research01 Jun 1994
Pediatric Research

Volume: 35, P: 633-636
Towards host-directed therapies for tuberculosis

The treatment of tuberculosis is based on combinations of drugs that directly targetMycobacterium tuberculosis. A new global initiative is now focusing on a complementary approach of developing adjunct host-directed therapies.

Alimuddin Zumla
Jeremiah Chakaya
Markus Maeurer
Comments & Opinion17 Jul 2015
Nature Reviews Drug Discovery

Volume: 14, P: 511-512
Protein Gene Product 9.5 (PGP 9.5) Is Not a Specific Marker of Neural and Nerve Sheath Tumors: An Immunohistochemical Study of 95 Mesenchymal Neoplasms

Lucas K Campbell
J Roby Thomas
Andrew L Folpe
Research01 Oct 2003
Modern Pathology

Volume: 16, P: 963-969
Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration

Z I Thomas
W Gibson
K P Williams
ResearchOpen Access19 Apr 2011
British Journal of Cancer

Volume: 104, P: 1575-1586
Genetic variation at traditional and novel allozyme loci, applied to interactions between wild and reared Salmo salar L. (Atlantic salmon)

Iain F Wilson
Elizabeth A Bourke
Thomas F Cross
Research01 Dec 1995
Heredity

Volume: 75, P: 578-588

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A crucial requirement for Hedgehog signaling in small cell lung cancer

Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease

Differences in the Effects in the Newborn Piglet of Various Nonsteroidal Antiinflammatory Drugs on Cerebral Blood Flow but Not on Cerebrovascular Prostaglandins

Vasopressin and Catecholamine Secretion during Metabolic Acidemia in the Ovine Fetus

Engagement and attrition in digital mental health: current challenges and potential solutions

Abnormal Adrenal Steroidogenesis in Growth-Retarded Newborn Infants

Towards host-directed therapies for tuberculosis

Protein Gene Product 9.5 (PGP 9.5) Is Not a Specific Marker of Neural and Nerve Sheath Tumors: An Immunohistochemical Study of 95 Mesenchymal Neoplasms

Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration

Genetic variation at traditional and novel allozyme loci, applied to interactions between wild and reared Salmo salar L. (Atlantic salmon)

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