A bioinspired nanosystem of cancer cell membrane-camouflaged SPIO@DOX-ICG nanoparticles was fabricated to realize precise cancer treatment by simultaneous chemotherapy, hyperthermia-therapy, and radiotherapy. The nanosystem achieved synergistic anticancer effects by antagonizing tumor hypoxia and reprograming the polarization of tumor associated macrophages to anti-tumor M1 phenotype, without causing toxic side effects on major organs.
- Yanyu Huang
- Chaoming Mei
- Tianfeng Chen
