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Showing 1–3 of 3 results
Advanced filters: Author: Timothy J. Trinklein Clear advanced filters
  • Amyloid plaques are a hallmark of Alzheimer’s disease. Better understanding of their biochemistry can inspire new biomarkers and therapeutics. Using multimodal mass spectrometry imaging, this work reveals surprising lipid heterogeneity in plaque microenvironments across the brain.

    • Timothy J. Trinklein
    • Stanislav S. Rubakhin
    • Jonathan V. Sweedler
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13
  • This overview of the ENCODE project outlines the data accumulated so far, revealing that 80% of the human genome now has at least one biochemical function assigned to it; the newly identified functional elements should aid the interpretation of results of genome-wide association studies, as many correspond to sites of association with human disease.

    • Ian Dunham
    • Anshul Kundaje
    • Ewan Birney
    ResearchOpen Access
    Nature
    Volume: 489, P: 57-74