Nature Search

Historic transposon mobilisation waves create distinct pools of adaptive variants in a major crop pathogen

In this study, the authors analysed a large genomic dataset to trace how jumping genes shaped the global spread of a major wheat pathogen and reveal bursts of activity over decades that drove adaptation to antifungals and crops, highlighting the power of big genomic data to track evolution.

Tobias Baril
Guido Puccetti
Daniel Croll
ResearchOpen Access12 Nov 2025
Nature Communications

Volume: 16, P: 1-17
Therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression

The acidic tumour microenvironment in melanoma drives immune evasion by cAMP in tumor-infiltrating monocytes. Here, the authors show that the release of an adenylate cyclase inhibitor from micelles restores antitumor immunity and, when combined with regulatory T cell depletion, leads to remission of established B16-F10-OVA tumors.

Kerstin Johann
Toszka Bohn
Christian Becker
ResearchOpen Access13 Oct 2021
Nature Communications

Volume: 12, P: 1-9
A systematic review and meta-analysis of nonrelapse mortality after CAR T cell therapy

In a systematic review and meta-analysis of nonrelapse mortality (NRM) following CAR T cell treatment in 7,604 patients with lymphoma and myeloma, almost half of cases were atrributable to infections and NRM estimates varied across both tumor types and CAR T cell products

David M. Cordas dos Santos
Tobias Tix
Kai Rejeski
Research08 Jul 2024
Nature Medicine

Volume: 30, P: 2667-2678
Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease

Deposition and spreading of amyloid-β pathology in mice requires binding to microglia-released ASC specks.

Carmen Venegas
Sathish Kumar
Michael T. Heneka
Research21 Dec 2017
Nature

Volume: 552, P: 355-361
Mixtures of organic micropollutants exacerbated in vitro neurotoxicity of prymnesins and contributed to aquatic toxicity during a toxic algal bloom

In summer 2022 an enormous fish kill was observed in the Oder River as a consequence of prymnesins produced by an algal bloom. An investigation of the exposure of aquatic life and human cells to the contaminated Oder water revealed the presence of neurotoxicants, which are attributed to B-type prymnesins, with minor contributions by organic micropollutants.

Beate I. Escher
Jörg Ahlheim
Elisabeth Varga
ResearchOpen Access06 Sept 2024
Nature Water

Volume: 2, P: 889-898
Colchicine in patients with aortic stenosis undergoing transcatheter aortic valve replacement: a double-blind randomized trial

An inflammatory process may increase the risk of arrhythmias after transcatheter aortic valve replacement. Here, the authors show that periprocedural treatment with colchicine may reduce the incidence of new-onset arrhythmias and subclinical leaflet thrombosis after transcatheter aortic valve replacement.

Christoph Ryffel
Jonas Lanz
Thomas Pilgrim
ResearchOpen Access15 Jul 2025
Nature Communications

Volume: 16, P: 1-11
Attenuated growth factor signaling during cell death initiation sensitizes membranes towards peroxidation

Aberrant redox homeostasis links lipid metabolism and cell death programs. Here, authors reveal how cell stress reduces growth factor signaling, enriching polyunsaturated fatty acids in phospholipids and sensitizing membranes to oxidative damage.

André Gollowitzer
Helmut Pein
Andreas Koeberle
ResearchOpen Access25 Feb 2025
Nature Communications

Volume: 16, P: 1-31
The impact of capsaicinoids on APP processing in Alzheimer’s disease in SH-SY5Y cells

Marcus O. W. Grimm
Tamara Blümel
Tobias Hartmann
ResearchOpen Access08 Jun 2020
Scientific Reports

Volume: 10, P: 1-16
Attenuated effector T cells are linked to control of chronic HBV infection

Heim et al. investigate the role of CD8⁺ T cells specific to HBV polymerase in the context of chronic HBV infection. They identify a unique subset of CD8⁺ T cells with an attenuated effector function. The attenuation is driven by TGFβ signaling, offering new insights into the immune landscape of chronic HBV infection and suggesting potential therapeutic avenues for modulating these cells to enhance viral control.

Kathrin Heim
Sagar
Maike Hofmann
ResearchOpen Access28 Aug 2024
Nature Immunology

Volume: 25, P: 1650-1662
Primary structure and expression of bovine poly(A) polymerase

Tobias Raabe
F. J. Bollum
James L. Manley
Research19 Sept 1991
Nature

Volume: 353, P: 229-234
Modelling armed conflict risk under climate change with machine learning and time-series data

Using machine learning, the authors reveal that stable background conditions explain most variation in armed conflict risk worldwide. Positive temperature deviations and precipitation extremes also increase the risk of conflict onset and incidence.

Quansheng Ge
Mengmeng Hao
Tobias Ide
ResearchOpen Access20 May 2022
Nature Communications

Volume: 13, P: 1-8
Myriapod genomes reveal ancestral horizontal gene transfer and hormonal gene loss in millipedes

Myriapods play an important ecological role in soil and forest ecosystems. Here the authors analyse nine myriapod genomes, showing rapid evolution of distinct genomic pathways in centipede and millipede lineages, shaped by differing ecological pressures.

Wai Lok So
Wenyan Nong
Jerome H. L. Hui
ResearchOpen Access30 May 2022
Nature Communications

Volume: 13, P: 1-12
Reply to ‘Sampling bias does not exaggerate climate–conflict claims’

Tobias Ide
Jon Barnett
Courtland Adams
Correspondence30 May 2018
Nature Climate Change

Volume: 8, P: 442-443
Bispecific antibodies targeting BCMA or GPRC5D are highly effective in relapsed myeloma after CAR T-cell therapy

Maximilian Merz
Danai Dima
Nico Gagelmann
ResearchOpen Access05 Dec 2024
Blood Cancer Journal

Volume: 14, P: 1-8
Milestone in predicting core plasma turbulence: successful multi-channel validation of the gyrokinetic code GENE

Plasma turbulence is the main driver to deteriorate the performance of fusion power plants. This work presents an unprecedented comparison of plasma turbulence between experiment and simulation, proving that the gyrokinetic model GENE reached a high level of maturity to predict core turbulence.

Klara Höfler
Tobias Görler
S. Zoletnik
ResearchOpen Access15 Mar 2025
Nature Communications

Volume: 16, P: 1-11
Autologous T cell therapy for PRAME⁺ advanced solid tumors in HLA-A*02⁺ patients: a phase 1 trial

In a non-prespecified interim analysis of a phase 1 trial, autologous PRAME-directed TCR T cell therapy was safe and elicited durable responses in patients with recurrent and/or treatment-refractory PRAME⁺ advanced solid tumors, including melanoma and synovial sarcoma.

Martin Wermke
Dejka M. Araujo
Cedrik M. Britten
ResearchOpen Access09 Apr 2025
Nature Medicine

Volume: 31, P: 2365-2374
Facile access to fused 2D/3D rings via intermolecular cascade dearomative [2 + 2] cycloaddition/rearrangement reactions of quinolines with alkenes

Hybrid 2D/3D ring systems have emerged as important scaffolds in medicinal chemistry, but efficient protocols for their synthesis are scarce. Now, energy-transfer-mediated cascade dearomative [2 + 2] cycloaddition/rearrangement reactions are developed to provide facile access to pyridine-fused 2D/3D ring systems.

Jiajia Ma
Shuming Chen
Frank Glorius
ResearchOpen Access25 May 2022
Nature Catalysis

Volume: 5, P: 405-413
The MyoPulser field stimulator, a do it yourself programmable electronic pacemaker for contracting cells and tissues

Christiane Ott
Tobias Jung
ResearchOpen Access11 Feb 2023
Scientific Reports

Volume: 13, P: 1-13
Hemocompatibility of new magnetically-levitated centrifugal pump technology compared to the CentriMag adult pump

David Schibilsky
Setsuo Takatani
Christian Schlensak
ResearchOpen Access16 Dec 2020
Scientific Reports

Volume: 10, P: 1-8
Sampling bias in climate–conflict research

A systematic review shows that climate–conflict research tends to focus on a few accessible regions characterized by violent conflict rather than those most vulnerable to climate change, which may inflate the perceived prevalence of links between climate change and violent conflict.

Courtland Adams
Tobias Ide
Adrien Detges
Research12 Feb 2018
Nature Climate Change

Volume: 8, P: 200-203
Standardized wireless deep brain stimulation system for mice

Alexander Grotemeyer
Tobias Petschner
Chi Wang Ip
ResearchOpen Access14 Aug 2024
npj Parkinson's Disease

Volume: 10, P: 1-11
Th17.1 cell driven sarcoidosis-like inflammation after anti-BCMA CAR T cells in multiple myeloma

Alexander M. Leipold
Rudolf A. Werner
Leo Rasche
ResearchOpen Access31 Jan 2023
Leukemia

Volume: 37, P: 650-658
Self-reported childhood family adversity is linked to an attenuated gain of trust during adolescence

The authors examined how family experiences are linked to the development of trust in adolescence and young adulthood. They show that trust increases over time but self-reported family adversity can hinder this, and trust may act as a resilience factor in maintaining positive peer relations.

Andrea M. F. Reiter
Andreas Hula
Raymond J. Dolan
ResearchOpen Access30 Oct 2023
Nature Communications

Volume: 14, P: 1-14
Varying climatic-social-geographical patterns shape the conflict risk at regional and global scales

Mengmeng Hao
Fangyu Ding
Dong Jiang
ResearchOpen Access17 Aug 2022
Humanities and Social Sciences Communications

Volume: 9, P: 1-8

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