Nature Search

Stabilization of Oligo(butyl isocyanate) by Acetyl End-Capping

Koichi Ute
Toshiya Asai
Koichi Hatada
Research01 Apr 1995
Polymer Journal

Volume: 27, P: 445-448
Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch

Shuichi Igarashi
Reiji Koide
Shoji Tsuji
Research01 Feb 1998
Nature Genetics

Volume: 18, P: 111-117
Ancestral sequence reconstruction as a tool for structural analysis of modular polyketide synthases

Modular polyketide synthases (PKSs) are multi-domain enzymes responsible for the biosynthesis of polyketide antibiotics. Here, authors show the potential of ancestral sequence reconstruction to facilitate structural analysis of modular PKSs.

Taichi Chisuga
Shota Takinami
Akimasa Miyanaga
ResearchOpen Access25 Jul 2025
Nature Communications

Volume: 16, P: 1-13
Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci

Chiea Chuen Khor, Tin Aung, Francesca Pasutto, Janey Wiggs and colleagues report a global genome-wide association study of exfoliation syndrome and a fine-mapping analysis of a previously identified disease-associated locus, LOXL1. They identify a rare protective variant in LOXL1 exclusive to the Japanese population and five new common variant susceptibility loci.

Tin Aung
Mineo Ozaki
Chiea Chuen Khor
Research29 May 2017
Nature Genetics

Volume: 49, P: 993-1004
Uphill energy transfer mechanism for photosynthesis in an Antarctic alga

A light-harvesting chlorophyll-binding protein complex from an Antarctic green alga called Prasiola crispa can excite photosystem II with low energy far-red light. Here, through Cryo-EM analysis, the authors reveal its ring-shaped structure with 11-fold symmetry at 3.13 Å resolution.

Makiko Kosugi
Masato Kawasaki
Toshiya Senda
ResearchOpen Access15 Feb 2023
Nature Communications

Volume: 14, P: 1-14
Correction: Corrigendum: A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome

Tin Aung
Mineo Ozaki
Chiea-Chuen Khor
Amendments and Corrections27 May 2015
Nature Genetics

Volume: 47, P: 689
Low-latitude mesopelagic nutrient recycling controls productivity and export

To facilitate more accurate long-term projections of primary production and export over oceanic low latitudes (LLs), we identified the first-order importance of the temperature dependence of remineralization of the LL nutrient reservoir, with this serving to enhance LL mesopelagic retention under warming.

Keith B. Rodgers
Olivier Aumont
Ryohei Yamaguchi
Research21 Aug 2024
Nature

Volume: 632, P: 802-807
Submesoscale transition from geostrophic flows to internal waves in the northwestern Pacific upper ocean

Satellite altimeters resolution poorly capture mesoscale signals in the upper ocean. Here, the authors analyse shipboard Acoustic Doppler Current Profiler measurements from the northwest Pacific, and show that balanced geostrophic flows and unbalanced internal waves comprise upper ocean velocities.

Bo Qiu
Toshiya Nakano
Patrice Klein
ResearchOpen Access09 Jan 2017
Nature Communications

Volume: 8, P: 1-10
A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome

Tin Aung, Chiea-Chuen Khor and colleagues report the results of a genome-wide association study of exfoliation syndrome. They replicate a known association at LOXL1 and identify a previously unreported association at CACNA1A.

Tin Aung
Mineo Ozaki
Chiea-Chuen Khor
Research23 Feb 2015
Nature Genetics

Volume: 47, P: 387-392
Association between amorphous calcium-phosphate ratios in circulating calciprotein particles and prognostic biomarkers in hemodialysis patients

Kimihiko Nakamura
Naohito Isoyama
Makoto Kuro-o
ResearchOpen Access29 Jul 2022
Scientific Reports

Volume: 12, P: 1-8
Increased cerebrospinal fluid fibrinogen in major depressive disorder

Kotaro Hattori
Miho Ota
Hiroshi Kunugi
ResearchOpen Access17 Jun 2015
Scientific Reports

Volume: 5, P: 1-9
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
Differential brain volume between obese and underweight cognitively normal older adults with frailty in the JPSC-AD

Naoki Ishizuka
Hiroshi Akasaka
Yutaka Kiyohara
ResearchOpen Access04 Jun 2025
Scientific Reports

Volume: 15, P: 1-12
Combined treatment with mesenchymal stem cells and therapeutic hypothermia for neonatal hypoxic ischemic encephalopathy: a phase 1/2 randomized trial

Kazuko Wada
Akihito Takeuchi
Satoshi Kusuda
ResearchOpen Access10 May 2025
Scientific Reports

Volume: 15, P: 1-8
Comparative analysis of necrotizing enterocolitis in preterm infants born in Japan and born to mothers of Japanese ethnicity in California

Satoshi Kusuda
Mihoko V. Bennett
Asao Yara
ResearchOpen Access22 Mar 2025
Scientific Reports

Volume: 15, P: 1-11
Long-term effects of ipragliflozin on blood pressure in patients with type 2 diabetes: insights from the randomized PROTECT trial

Yuichi Saito
Atsushi Tanaka
Kosuke Nishio
Research14 Nov 2023
Hypertension Research

Volume: 47, P: 168-176
Estimation of Basin-scale turbulence distribution in the North Pacific Ocean using CTD-attached thermistor measurements

Yasutaka Goto
Ichiro Yasuda
Toshiya Nakano
ResearchOpen Access13 Jan 2021
Scientific Reports

Volume: 11, P: 1-13
Deep convolutional neural network-based algorithm for muscle biopsy diagnosis

The authors developed a deep convolutional neural network-based algorithm to support pathological muscle diagnosis. The algorithm differentiated idiopathic inflammatory myopathies and outperformed nine human physicians under limited diseases and conditions. These results suggest that the algorithm has the potential to be used directly in clinical settings.

Yoshinori Kabeya
Mariko Okubo
Ichizo Nishino
Research02 Oct 2021
Laboratory Investigation

Volume: 102, P: 220-226
Arpp, a New Homolog of Carp, Is Preferentially Expressed in Type 1 Skeletal Muscle Fibers and Is Markedly Induced by Denervation

Yoshiyuki Tsukamoto
Takao Senda
Masatsugu Moriyama
Research01 May 2002
Laboratory Investigation

Volume: 82, P: 645-655
Green tea consumption and cerebral white matter lesions in community-dwelling older adults without dementia

Shutaro Shibata
Moeko Noguchi-Shinohara
Yutaka Kiyohara
ResearchOpen Access07 Jan 2025
npj Science of Food

Volume: 9, P: 1-8
Reduced cerebrospinal fluid ethanolamine concentration in major depressive disorder

Shintaro Ogawa
Kotaro Hattori
Hiroshi Kunugi
ResearchOpen Access15 Jan 2015
Scientific Reports

Volume: 5, P: 1-8
Glucose metabolism and smaller hippocampal volume in elderly people with normal cognitive function

Ayano Shima
Moeko Noguchi-Shinohara
Yutaka Kiyohara
ResearchOpen Access09 Sept 2024
npj Aging

Volume: 10, P: 1-10
Serum high-sensitivity C-reactive protein and dementia in a community-dwelling Japanese older population (JPSC-AD)

Ayumi Tachibana
Jun-ichi Iga
Yutaka Kiyohara
ResearchOpen Access28 Mar 2024
Scientific Reports

Volume: 14, P: 1-9
Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls

Hiroki Masuda
Masahiro Mori
Satoshi Kuwabara
ResearchOpen Access03 Aug 2023
Scientific Reports

Volume: 13, P: 1-14

Search

Stabilization of Oligo(butyl isocyanate) by Acetyl End-Capping

Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch

Ancestral sequence reconstruction as a tool for structural analysis of modular polyketide synthases

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci

Uphill energy transfer mechanism for photosynthesis in an Antarctic alga

Correction: Corrigendum: A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome

Low-latitude mesopelagic nutrient recycling controls productivity and export

Submesoscale transition from geostrophic flows to internal waves in the northwestern Pacific upper ocean

A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome

Association between amorphous calcium-phosphate ratios in circulating calciprotein particles and prognostic biomarkers in hemodialysis patients

Increased cerebrospinal fluid fibrinogen in major depressive disorder

Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Differential brain volume between obese and underweight cognitively normal older adults with frailty in the JPSC-AD

Combined treatment with mesenchymal stem cells and therapeutic hypothermia for neonatal hypoxic ischemic encephalopathy: a phase 1/2 randomized trial

Comparative analysis of necrotizing enterocolitis in preterm infants born in Japan and born to mothers of Japanese ethnicity in California

Long-term effects of ipragliflozin on blood pressure in patients with type 2 diabetes: insights from the randomized PROTECT trial

Estimation of Basin-scale turbulence distribution in the North Pacific Ocean using CTD-attached thermistor measurements

Deep convolutional neural network-based algorithm for muscle biopsy diagnosis

Arpp, a New Homolog of Carp, Is Preferentially Expressed in Type 1 Skeletal Muscle Fibers and Is Markedly Induced by Denervation

Green tea consumption and cerebral white matter lesions in community-dwelling older adults without dementia

Reduced cerebrospinal fluid ethanolamine concentration in major depressive disorder

Glucose metabolism and smaller hippocampal volume in elderly people with normal cognitive function

Serum high-sensitivity C-reactive protein and dementia in a community-dwelling Japanese older population (JPSC-AD)

Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls

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