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Showing 1–2 of 2 results
Advanced filters: Author: Tuerxunjiang Maimaiti Clear advanced filters

  • The MFS-type tripartite efflux pump EmrAB-TolC mediates resistance to multiple antimicrobial drugs. Here the authors report the high-resolution structure of the EmrAB TolC pump, along with functional data that support a model for one-step drug transport across the entire envelope of Gram-negative bacteria.

    • Zhaojun Zhong
    • Tuerxunjiang Maimaiti
    • Dijun Du
    ResearchOpen Access
    Nature Communications
    P: 1-15

  • The fusion of viruses with cellular membranes is an essential step in the life cycle of enveloped viruses. Here, the authors present cryo-electron microscopy (cryo-EM) structures of a prototype class III fusion protein GP64 in prefusion and early intermediate states, and show that the coordination between multiple histidine residues acts as a pH sensor and activator.

    • Jinliang Guo
    • Shangrong Li
    • Dijun Du
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14