Transesterification reactions are essential in organic chemistry, however, performing these reactions in aqueous media is challenging due to the competing hydrolysis reaction. Here, the authors report a mutant of alcohol oxidase from Phanerochaete chrysosporium (PcAOx-VPN) that exhibits no hydrolytic activity, enabling transesterification reactions in water.
- Bin Wu
- Yunjian Ma
- Yonghua Wang
