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Showing 1–5 of 5 results
Advanced filters: Author: Una O’Doherty Clear advanced filters

  • The development of effective antiretroviral therapies has greatly improved the disease prognosis for patients with HIV. However, the limitations of these therapies have renewed interest in developing alternative treatment strategies. Here, a group of experts from the International AIDS Society discuss the research steps that need to be taken to achieve the ultimate objective — a cure for HIV.

    • Steven G. Deeks
    • Brigitte Autran
    • Françoise Barré-Sinoussi
    Reviews
    Nature Reviews Immunology
    Volume: 12, P: 607-614

  • Potent chimaeric antigen receptor T cells can be generated within one day from T cells derived from peripheral blood without the need for T-cell activation.

    • Saba Ghassemi
    • Joseph S. Durgin
    • Michael C. Milone
    Research
    Nature Biomedical Engineering
    Volume: 6, P: 118-128

  • How HIV reservoirs are shaped over time on antiviral therapy is poorly understood. Here, the authors analyze the dynamics of the HIV reservoir by longitudinal proviral sequencing revealing that HIV reservoir expression can contribute to its clearance and paradoxically even to its persistence.

    • Marilia Rita Pinzone
    • D. Jake VanBelzen
    • Una O’Doherty
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-12