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Showing 1–4 of 4 results
Advanced filters: Author: Vannary Meas-Yedid Clear advanced filters

  • Immunotherapy is transforming cancer treatment, with immune cell distribution in the tumour microenvironment key to predicting outcomes. Here, authors provide a robust framework to analyse spatial patterns, distinguishing true immune associations from random accumulations, offering insights into immunotherapy responses.

    • Mohamed M. Benimam
    • Vannary Meas-Yedid
    • Jean-Christophe Olivo-Marin
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-20

  • ‘Missing self’ is a mode of natural killer (NK) cell activation aimed to detect the lack of HLA-I molecules on infected or neoplastic cells. Here, the authors show that mismatch between donor HLA-I and cognate receptors on recipient NK cells mediates microvascular inflammation-associated graft rejection, a pathology that is preventable by mTOR inhibition.

    • Alice Koenig
    • Chien-Chia Chen
    • Olivier Thaunat
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-17

  • In eukaryotic cells, a subset of microtubules undergoes acetylation, resulting in stabilization: here, clathrin-coated pits are shown to control microtubule acetylation through a direct interaction between the α-tubulin acetyltransferase αTAT1 and the clathrin adaptor AP2, promoting directional cell migration.

    • Guillaume Montagnac
    • Vannary Meas-Yedid
    • Philippe Chavrier
    Research
    Nature
    Volume: 502, P: 567-570

  • Icy is a collaborative platform for biological image analysis that extends reproducible research principles by facilitating and stimulating the contribution and sharing of algorithm-based tools and protocols between researchers.

    • Fabrice de Chaumont
    • Stéphane Dallongeville
    • Jean-Christophe Olivo-Marin
    Reviews
    Nature Methods
    Volume: 9, P: 690-696