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Showing 1–2 of 2 results
Advanced filters: Author: Varsha Venkatarangan Clear advanced filters

  • The authors demonstrate the multifaceted role of LYSET in stabilizing GNPT at the Golgi, by resolving the topology of LYSET and identifying several critical regions for LYSET function and stability.

    • Xi Yang
    • Balraj Doray
    • Ming Li
    ResearchOpen Access
    Nature Communications
    P: 1-18

  • Lysosomal biogenesis errors often result in diseases including mucolipidosis. Here Zhang and Yang et al. identify TMEM251/GCAF as a mannose-6-phosphate modification regulator that is necessary for correct lysosomal targeting, and classify Mucolipidosis Type V as resulting from GCAF mutations.

    • Weichao Zhang
    • Xi Yang
    • Ming Li
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-17