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Showing 1–3 of 3 results
Advanced filters: Author: Vincent Portegijs Clear advanced filters

  • DNA damage threatens genome stability, but its dynamics in living systems remain difficult to track. Here, the authors engineer MCPH1-based protein probes that specifically recognize γH2AX, enabling real-time visualization and mapping of DNA damage across diverse cellular and organismal contexts.

    • Richard Cardoso da Silva
    • Kristeli Eleftheriou
    • Tuncay Baubec
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • The LIN-5/NuMA pathway is needed to correctly position the mitotic spindle for asymmetric division. Now van den Heuvel and colleagues find that polarity kinase aPKC–PKC-3 phosphorylates LIN-5 to direct the localization of the spindle in the early embryos of Caenorhabditis elegans.

    • Matilde Galli
    • Javier Muñoz
    • Sander van den Heuvel
    Research
    Nature Cell Biology
    Volume: 13, P: 1132-1138