The difficulties that are currently inherent in early diagnosis of acute kidney injury could be overcome by the introduction of biomarkers into routine clinical practice. Here, Bruce Molitoris and colleagues provide an update of the status of development of biomarkers for this indication. Transcriptomics, proteomics, and gene array and imaging technologies are just some of the methods being harnessed to drive the discovery process. Subsequent validation in high quality clinical trials will be essential.
- Bruce A Molitoris
- Vyacheslav Y Melnikov
- Jonathan Himmelfarb
