The cell wall of the oral bacterium Streptococcus mutans carries SCC, a rhamnose-containing polysaccharide with glucose side-chain decorations. Here, the authors report the SCC structure and the synthesis mechanism, revealing how four glucosyltransferases work together to synthesize the side-chains.
- Jeffrey S. Rush
- Svetlana Zamakhaeva
- Natalia Korotkova
