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A multimodal vision–language model for generalizable annotation-free pathology localization

An annotation-free vision–language model based on contrastive learning performs pathology localization and clinical diagnosis on a wide variety of medical image datasets.

Hao Yang
Hong-Yu Zhou
Shanshan Wang
Research06 Jan 2026
Nature Biomedical Engineering

P: 1-15
Denosumab attenuates knee osteoarthritis progression by inhibiting synovial inflammation via the RANK/TRAF6/FSTL1 signalling

Synovitis is a key early driver of osteoarthritis (OA), and RANKL contributes to cartilage degradation in OA. Here the authors show that denosumab, an anti-RNKL antibody, reduces synovitis and delays OA progression in animal models and patients.

Yuxiang Hu
Wei Chen
Wei Tong
ResearchOpen Access17 Dec 2025
Nature Communications

Volume: 16, P: 1-18
Magnetotransport evidence for the coexistence of two-dimensional superconductivity and ferromagnetism at (111)-oriented a-CaZrO₃/KTaO₃ interfaces

The authors report magnetotransport evidence for the coexistence of a two-dimensional (2D) superconducting state and a 2D ferromagnetic state at the interface between amorphous CaZrO₃ film and KTaO₃ single crystal. Moreover, the magnetoresistance hysteresis reaches a maximum near the superconducting transition temperature.

Hui Zhang
Yinan Xiao
Jinsong Zhang
ResearchOpen Access28 Mar 2025
Nature Communications

Volume: 16, P: 1-11
Delineation of Natural Killer Cell Differentiation from Myeloid Progenitors in Human

Qingfeng Chen
Weijian Ye
Jianzhu Chen
ResearchOpen Access12 Oct 2015
Scientific Reports

Volume: 5, P: 1-12
Asperosaponin VI promotes bone marrow stromal cell osteogenic differentiation through the PI3K/AKT signaling pathway in an osteoporosis model

Ke Ke
Qi Li
Huali Shi
ResearchOpen Access19 Oct 2016
Scientific Reports

Volume: 6, P: 1-9
Impact of air pollution prevention and control on urban green economy efficiency: evidence from China

Han Zhang
Weijian Dou
ResearchOpen Access13 Nov 2024
Scientific Reports

Volume: 14, P: 1-21
First-line treatment of anti-EGFR monoclonal antibody cetuximab β plus FOLFIRI versus FOLFIRI alone in Chinese patients with RAS/BRAF wild-type metastatic colorectal cancer: a randomized, phase 3 trial

Yuankai Shi
Yi Ba
Sheng Hou
ResearchOpen Access07 May 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-9
DAB2IP inhibits glucose uptake by modulating HIF-1α ubiquitination under hypoxia in breast cancer

Hongliang Dong
Weiyi Jia
Jie Shen
ResearchOpen Access11 Jun 2024
Oncogenesis

Volume: 13, P: 1-13
Detection and Categorization of Diarrheagenic Escherichia coli with Auto-microfluidic Thin-film Chip Method

Zhenyu Yun
Lian Zeng
Haodong Chen
ResearchOpen Access27 Aug 2018
Scientific Reports

Volume: 8, P: 1-10

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A multimodal vision–language model for generalizable annotation-free pathology localization

Denosumab attenuates knee osteoarthritis progression by inhibiting synovial inflammation via the RANK/TRAF6/FSTL1 signalling

Magnetotransport evidence for the coexistence of two-dimensional superconductivity and ferromagnetism at (111)-oriented a-CaZrO₃/KTaO₃ interfaces

Delineation of Natural Killer Cell Differentiation from Myeloid Progenitors in Human

Asperosaponin VI promotes bone marrow stromal cell osteogenic differentiation through the PI3K/AKT signaling pathway in an osteoporosis model

Impact of air pollution prevention and control on urban green economy efficiency: evidence from China

First-line treatment of anti-EGFR monoclonal antibody cetuximab β plus FOLFIRI versus FOLFIRI alone in Chinese patients with RAS/BRAF wild-type metastatic colorectal cancer: a randomized, phase 3 trial

DAB2IP inhibits glucose uptake by modulating HIF-1α ubiquitination under hypoxia in breast cancer

Detection and Categorization of Diarrheagenic Escherichia coli with Auto-microfluidic Thin-film Chip Method

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