Nature Search

Hepatic GPR110 contributes to sex disparity in the development of MASH through oestrogen receptor α-dependent signalling

Hepatocyte-specific GPR110 mediates metabolic dysfunction-associated steatohepatitis progression by regulating hepatic oestrogen sensitivity in a sex-specific manner, specifically in female mice.

Fang Yang
Wei Wang
Zhe Huang
Research05 Jan 2026
Nature Metabolism

Volume: 8, P: 116-138
Hospital-treated infectious diseases and the risk of epilepsy in older age

Infectious diseases can cause acute seizures. Here the authors investigate their long-term impact on the risk of epilepsy for older adults. They find that hospital-treated infectious diseases have a lasting impact on the development of epilepsy in older age, and that cardiovascular risk factors may exacerbate this impact.

Qiyuan Zhuang
Yihan Hu
Fang Fang
ResearchOpen Access04 Nov 2025
Nature Aging

Volume: 5, P: 2188-2196
Shared genetic architecture between eating disorders, mental health conditions, and cardiometabolic diseases: a comprehensive population-wide study across two countries

Here, the authors’ findings highlight genetic overlap between eating disorders, mental disorders, and cardiometabolic diseases, supporting the need for integrated treatment strategies across physical and mental health care.

Joeri Meijsen
Kejia Hu
Nadia Micali
ResearchOpen Access04 Jul 2025
Nature Communications

Volume: 16, P: 1-10
Non-invasive early detection of cancer four years before conventional diagnosis using a blood test

Patients whose disease is diagnosed in its early stages have better outcomes. In this study, the authors develop a non invasive blood test based on circulating tumor DNA methylation that can potentially detect cancer occurrence even in asymptomatic patients.

Xingdong Chen
Jeffrey Gole
Li Jin
ResearchOpen Access21 Jul 2020
Nature Communications

Volume: 11, P: 1-10
Pro-phagocytic function and structural basis of GPR84 signaling

GPR84 is an important GPCR regulating macrophage function. Here, the authors show the pro-phagocytic function of the GPR84-Gi signaling axis in native macrophages and determine a cryo-EM structure of the GPR84-Gi complex with a synthetic agonist.

Xuan Zhang
Yujing Wang
Cheng Zhang
ResearchOpen Access14 Sept 2023
Nature Communications

Volume: 14, P: 1-12
Implementing machine learning in bipolar diagnosis in China

Yantao Ma
Jun Ji
Xin Yu
ResearchOpen Access18 Nov 2019
Translational Psychiatry

Volume: 9, P: 1-7
Pre-spermatorrhea state: a novel therapeutic paradigm for the management of non-organic delayed ejaculation and anejaculation

Dawei Gao
Wenxiu Zhang
Baofang Jin
Correspondence29 Sept 2025
International Journal of Impotence Research

P: 1-4
The effects of dynamic daylight-like light on the rhythm, cognition, and mood of irregular shift workers in closed environment

Jingxin Nie
Tianhang Zhou
Bo Shen
ResearchOpen Access22 Jun 2021
Scientific Reports

Volume: 11, P: 1-11
Manipulating interstitial carbon atoms in the nickel octahedral site for highly efficient hydrogenation of alkyne

Design and synthesis of non-noble metal catalysts is crucial for highly-efficient hydrogenation. Here, the interstitial sites in nickel are manipulated with zinc and filled by dissociated carbon atoms, which drastically improve the selectivity/stability in acetylene hydrogenation reaction.

Yiming Niu
Xing Huang
Bingsen Zhang
ResearchOpen Access03 Jul 2020
Nature Communications

Volume: 11, P: 1-9
Evaluation of the immunomodulatory effects of anti-COVID-19 TCM formulae by multiple virus-related pathways

Liansheng Qiao
Wenting Huang
Jing Cheng
ResearchOpen Access04 Feb 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-3

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