Nature Search

Efficacy and safety of low-dose interleukin 2 for Behçet’s syndrome: a randomized, placebo-controlled, double-blind, phase 2 clinical trial

Behçet’s syndrome is a chronic inflammatory disease with oral ulcers being the most common symptom. Here authors present results from a phase 2 randomized double-blind placebo-controlled clinical trial that shows that systemic low dose interleukin-2 could be safely administered to these patients, and the therapy may improve their quality of life.

Tian Liu
Wenyan Zhou
Zhanguo Li
ResearchOpen Access07 Jan 2026
Nature Communications

P: 1-8
Surface indium vacancies promote photocatalytic H₂O₂ production over In₂S₃

Photocatalytic oxygen reduction reaction to produce H₂O₂ awaits in-depth knowledge for the design of active photocatalysts. Here, the authors identify that surface indium vacancies are the key to opening the activity of In₂S₃ for H₂O₂ photosynthesis.

Qiong Zhu
Jingjing Su
Xiaoxiang Xu
ResearchOpen Access25 Nov 2025
Nature Communications

Volume: 16, P: 1-13
Liquid-based encapsulation for implantable bioelectronics across broad pH environments

Medical devices face stability challenges in extreme pH conditions. Here, the authors report a liquid-based encapsulation approach that achieves year-long encapsulation in acidic conditions

He Sun
Xiaoting Xue
Yi Zhang
ResearchOpen Access25 Jan 2025
Nature Communications

Volume: 16, P: 1-12
RETRACTED ARTICLE: Modified box dimension and average weighted receiving time on the weighted fractal networks

Meifeng Dai
Yanqiu Sun
Weiyi Su
ResearchOpen Access15 Dec 2015
Scientific Reports

Volume: 5, P: 1-10
Integrated application of transcriptomics and metabolomics provides insights into gonadal differentiation in Mesocentrotus nudus

Abudula Abulizi
Weiyi Su
Yaqing Chang
ResearchOpen Access20 Dec 2025
Scientific Reports

Volume: 16, P: 1-14
A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases

HECT type E3 ligases are key regulators of cell growth and proliferation. Here the authors present the crystal structures of the Nedd4 family E3 ligase WWP1 in a closed and semi-open state and in combination with mutagenesis experiments identify a multi-lock regulatory mechanism that allows the fine-tuning of activities of Nedd4 family E3 ligases.

Zhen Wang
Ziheng Liu
Wenyu Wen
ResearchOpen Access18 Jul 2019
Nature Communications

Volume: 10, P: 1-15
Prediction of antipsychotic drug efficacy for schizophrenia treatment based on neural features of the resting-state functional connectome

Song Liu
Meng Wang
Yongfeng Yang
ResearchOpen Access10 Apr 2025
Translational Psychiatry

Volume: 15, P: 1-9
Porous polycarbene-bearing membrane actuator for ultrasensitive weak-acid detection and real-time chemical reaction monitoring

The design of soft actuators which show high sensitivity and allow for simultaneous interaction with multiple stimuli still remains a challenge. Here the authors demonstrate a highly sensitive proton actuator which allows monitoring of an entire process of chemical reactions that comprise multiple stimuli and operational steps.

Jian-Ke Sun
Weiyi Zhang
Jiayin Yuan
ResearchOpen Access30 Apr 2018
Nature Communications

Volume: 9, P: 1-8
RNA sequencing provides insights into the evolution of lettuce and the regulation of flavonoid biosynthesis

Horticultural lettuce varieties vary considerably in phenotype. Here, via RNA-seq of 240 different lettuce accessions, the authors identify loci and expression patterns associated with flavonoid and anthocyanin content and show that cultivated lettuce likely arose via a single domestication event.

Lei Zhang
Wenqing Su
Hanhui Kuang
ResearchOpen Access22 Dec 2017
Nature Communications

Volume: 8, P: 1-12
Retraction Note: Modified box dimension and average weighted receiving time on the weighted fractal networks

Meifeng Dai
Yanqiu Sun
Weiyi Su
Amendments and CorrectionsOpen Access08 Apr 2020
Scientific Reports

Volume: 10, P: 1
A signal recognition particle receptor gene from the sea cucumber, Apostichopus japonicas

Jian Zhang
Zhihui Sun
Yaqing Chang
ResearchOpen Access27 Dec 2023
Scientific Reports

Volume: 13, P: 1-10
A database on the abundance of environmental antibiotic resistance genes

Wenjuan Xu
Zhizhen Pan
Qiansheng Huang
ResearchOpen Access27 Feb 2024
Scientific Data

Volume: 11, P: 1-9
Proteomic analysis of murine testes lipid droplets

Weiyi Wang
Suning Wei
Guoheng Xu
ResearchOpen Access10 Jul 2015
Scientific Reports

Volume: 5, P: 1-19
Two types of weight-dependent walks with a trap in weighted scale-free treelike networks

Meifeng Dai
Yue Zong
Weiyi Su
ResearchOpen Access24 Jan 2018
Scientific Reports

Volume: 8, P: 1-11

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Efficacy and safety of low-dose interleukin 2 for Behçet’s syndrome: a randomized, placebo-controlled, double-blind, phase 2 clinical trial

Surface indium vacancies promote photocatalytic H₂O₂ production over In₂S₃

Liquid-based encapsulation for implantable bioelectronics across broad pH environments

RETRACTED ARTICLE: Modified box dimension and average weighted receiving time on the weighted fractal networks

Integrated application of transcriptomics and metabolomics provides insights into gonadal differentiation in Mesocentrotus nudus

A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases

Prediction of antipsychotic drug efficacy for schizophrenia treatment based on neural features of the resting-state functional connectome

Porous polycarbene-bearing membrane actuator for ultrasensitive weak-acid detection and real-time chemical reaction monitoring

RNA sequencing provides insights into the evolution of lettuce and the regulation of flavonoid biosynthesis

Retraction Note: Modified box dimension and average weighted receiving time on the weighted fractal networks

A signal recognition particle receptor gene from the sea cucumber, Apostichopus japonicas

A database on the abundance of environmental antibiotic resistance genes

Proteomic analysis of murine testes lipid droplets

Two types of weight-dependent walks with a trap in weighted scale-free treelike networks

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