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Showing 1–3 of 3 results
Advanced filters: Author: Wiep van der Toorn Clear advanced filters

  • Cas12a3 nucleases constitute a distinct clade of type V CRISPR–Cas bacterial immune systems that preferentially cleave the 3′ tails of tRNAs after recognition of target RNA to induce growth arrest and block phage dissemination.

    • Oleg Dmytrenko
    • Biao Yuan
    • Chase L. Beisel
    ResearchOpen Access
    Nature
    Volume: 649, P: 1312-1321

  • Applications of nanopore direct RNA sequencing (dRNA) are limited by the lack of accurate and cost-effective sample multiplexing. Here, the authors report an ultra-fast and high accurate adapter-barcoding and demultiplexing approach for dRNA and demonstrate its application in SARS-CoV-2 viruses.

    • Wiep van der Toorn
    • Patrick Bohn
    • Max von Kleist
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • Oh, Hölzer et al., discuss the multidisciplinary approach used for monitoring the genomic and virological evolution of SARS-CoV-2 during the COVID-19 pandemic and its implications on public health in Germany. They emphasize the need for continuous surveillance and adaptation of public health strategies to address evolving viral threats.

    • Djin-Ye Oh
    • Martin Hölzer
    • Wiep van der Toorn
    ReviewsOpen Access
    Communications Medicine
    Volume: 5, P: 1-22