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Cell Death and Differentiation (1)
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Advanced filters: Author: Xialian Xi Clear advanced filters

A Gremlin 1-expressing splenic niche cell population restrains chronic myeloid leukemia by antagonizing the BMP pathway

Zhu and colleagues show that a subpopulation of spleen-derived fibroblasts secrete Gremlin 1, which suppresses chronic myeloid leukemia progression by inducing leukemia stem cell apoptosis through the BMP signaling pathway.

Jinming Wang
Penghui Xu
Helen He Zhu
Research17 Mar 2025
Nature Cancer

Volume: 6, P: 666-681
Zeb1-controlled metabolic plasticity enables remodeling of chromatin accessibility in the development of neuroendocrine prostate cancer

Deng Wang
Genyu Du
Helen He Zhu
Research23 Apr 2024
Cell Death & Differentiation

Volume: 31, P: 779-791

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A Gremlin 1-expressing splenic niche cell population restrains chronic myeloid leukemia by antagonizing the BMP pathway

Zeb1-controlled metabolic plasticity enables remodeling of chromatin accessibility in the development of neuroendocrine prostate cancer

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