Nature Search

Autonomous artificial intelligence prescribing a drug to prevent severe acute graft-versus-host disease in HLA-haploidentical transplants

Autonomous artificial intelligence (AI) models to replace human decision-making in medical intervention need thorough testing. Here authors present the results of a clinical trial, NCT05600855, in which daGOAT, a conditional autonomous artificial intelligence agent successfully makes the decision whether to prescribe an immune suppressive drug to prevent severe acute graft-versus-host disease following HLA-mismatched haematopoietic cell transplantation.

Junren Chen
Yigeng Cao
Erlie Jiang
ResearchOpen Access25 Sept 2025
Nature Communications

Volume: 16, P: 1-17
SL\((2,{\mathbb{C}})\) non-Abelian gauge fields in a photonic molecule array

Artificial gauge fields offer a powerful tool for engineering the topological phase of matter. Here, the authors propose a scheme to simulate an SL\((2,{\mathbb{C}})\) non-Abelian gauge field by coupled photonic molecules in synthetic space-frequency dimensions, which enables various Dirac semimetal transitions.

Zhaohui Dong
Xianfeng Chen
Luqi Yuan
ResearchOpen Access19 Nov 2025
Nature Communications

Volume: 16, P: 1-9
Involvement of JNK-initiated p53 accumulation and phosphorylation of p53 in pseudolaric acid B induced cell death

Xianfeng Gong
Minwei Wang
Takashi Ikejima
ResearchOpen Access01 Aug 2006
Experimental & Molecular Medicine

Volume: 38, P: 428-434
Parkinson’s disease: spatiotemporal regulation and therapeutic prospects of TREM2-mediated microglial responses

Keyuan Hou
Zhaowu An
Jianshe Wei
ReviewsOpen Access13 Jan 2026
npj Parkinson's Disease

P: 1-13
Poking cells for efficient vector-free intracellular delivery

The incorporation of foreign objects into cells can be used in various avenues of biological research, although crossing the cell membrane can be challenging. Here, the authors use a diamond nanoneedle array for enhanced delivery of various particles into cells, including neurons.

Ying Wang
Yang Yang
Peng Shi
Research29 Jul 2014
Nature Communications

Volume: 5, P: 1-9
Influence of the inclination angles on the stress distribution in the bottom plate under the deep residual coal pillar

Xianfeng Shi
Huan Yu
Shifang Qin
ResearchOpen Access07 Nov 2025
Scientific Reports

Volume: 15, P: 1-12
Targeting initial tumour–osteoclast spatiotemporal interaction to prevent bone metastasis

Tumour cell behaviour is an underdeveloped target for cancer intervention. Here the authors report on a spatiotemporal interaction between tumour cells and osteoclasts in initial bone metastases and propose a behaviour-targeting therapy with an in situ physical killing strategy.

Chenhui Gu
Pengfei Chen
Xianfeng Lin
Research18 Mar 2024
Nature Nanotechnology

Volume: 19, P: 1044-1054
Nickel-catalysed selective migratory hydrothiolation of alkenes and alkynes with thiols

Construction of C–S bonds via C–H functionalization is an attractive route to organosulfur compounds. Here, the authors show the synergistic combination of NiH-catalysed alkene isomerization and subsequent thiolation to afford remote hydrothiolation products from alkenes (or alkynes) and thiols under mild conditions.

Yulong Zhang
Xianfeng Xu
Shaolin Zhu
ResearchOpen Access15 Apr 2019
Nature Communications

Volume: 10, P: 1-9
Massively parallel variant-to-function mapping determines functional regulatory variants of non-small cell lung cancer

Determining the causal variants at GWAS loci is crucial for understanding genetic disease mechanisms. Here, the authors apply MPRA to perform non-small cell lung cancer (NSCLC) variant-to-function mapping at scale and propose distinct genetic architectures underlying NSCLC susceptibility.

Congcong Chen
Yang Li
Hongbing Shen
ResearchOpen Access06 Feb 2025
Nature Communications

Volume: 16, P: 1-16
Highly lethal genotype I and II recombinant African swine fever viruses detected in pigs

Potential recombination of African swine fever virus genotypes is not well understood. Here, Zhao et al. report naturally occurring ASFVs carrying mosaic genomes of genotype I and II and show that the recombinant virus is lethal in pigs and evades the immunity induced by genotype II live vaccine.

Dongming Zhao
Encheng Sun
Zhigao Bu
ResearchOpen Access29 May 2023
Nature Communications

Volume: 14, P: 1-10
A deep learning-based model for screening and staging pneumoconiosis

Liuzhuo Zhang
Ruichen Rong
Guanghua Xiao
ResearchOpen Access26 Jan 2021
Scientific Reports

Volume: 11, P: 1-7
Storing light near an exceptional point

Exceptional point introduces the ability to control and tune light propagation. Here the authors demonstrate a 90-μm-radius optical microcavity to store light, induced by nonlinear Brillouin scattering at room temperature.

Yicheng Zhu
Jiankun Hou
Wenjie Wan
ResearchOpen Access16 Sept 2024
Nature Communications

Volume: 15, P: 1-7
A multicenter phase 2 trial of camrelizumab plus famitinib for women with recurrent or metastatic cervical squamous cell carcinoma

Patients with recurrent or metastatic cervical cancer have limited therapeutic options. Here the authors report efficacy and safety of camrelizumab (anti-PD-1 antibody) in combination with famitinib (anti-angiogenic agent) in pre-treated recurrent or metastatic squamous cervical cancer.

Lingfang Xia
Qi Zhou
Xiaohua Wu
ResearchOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1-9
Molecular identification and quantification of defect sites in metal-organic frameworks with NMR probe molecules

Defects in porous materials can alter the pore structure and chemical properties. Here authors demonstrate an approach for studying defects in metal-organic frameworks using ³¹P NMR and probe molecules.

Jinglin Yin
Zhengzhong Kang
Xueqian Kong
ResearchOpen Access30 Aug 2022
Nature Communications

Volume: 13, P: 1-9
Pseudolaric acid B induces apoptosis via activation of c-Jun N-terminal kinase and caspase-3 in HeLa cells

Xianfeng Gong
Minwei Wang
Takashi Ikejima
ResearchOpen Access01 Dec 2004
Experimental & Molecular Medicine

Volume: 36, P: 551-556
Porous membrane with high curvature, three-dimensional heat-resistance skeleton: a new and practical separator candidate for high safety lithium ion battery

Junli Shi
Yonggao Xia
Zhaoping Liu
ResearchOpen Access05 Feb 2015
Scientific Reports

Volume: 5, P: 1-9
Optimization of wavefront reconstruction accuracy for conjugate shift differential absolute testing

Xueliang Zhu
Dasen Wang
Xianfeng Zheng
ResearchOpen Access16 Dec 2022
Scientific Reports

Volume: 12, P: 1-9
Evolution of the electronic structure in open-shell donor-acceptor organic semiconductors

The classical narrow bandgap donor-acceptor organic semiconductors show great application potential in organic electronics, bio-imaging and other fields. Here, the authors systematically and rigorously demonstrate their open-shell diradical character via experimental and theoretical investigation.

Zhongxin Chen
Wenqiang Li
Fei Huang
ResearchOpen Access07 Oct 2021
Nature Communications

Volume: 12, P: 1-10
Sequencing and de novo assembly of a near complete indica rice genome

High-quality reference genomes facilitate analysis of genome structure and variation. Here Duet al. create a near-complete assembly of the indicarice genome by combining single molecule sequencing with mapping data and fosmid sequences and identify genetic variants by comparison with other rice genomes.

Huilong Du
Ying Yu
Chengzhi Liang
ResearchOpen Access04 May 2017
Nature Communications

Volume: 8, P: 1-12
A novel capsule-based self-recovery system with a chloride ion trigger

Wei Xiong
Jiaoning Tang
Feng Xing
ResearchOpen Access08 Jun 2015
Scientific Reports

Volume: 5, P: 1-6
Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients

Yu Huang
Xianfeng Zhu
Hulan Hu
ResearchOpen Access02 Jun 2025
Scientific Reports

Volume: 15, P: 1-11
Eye in outer space: satellite imageries of container ports can predict world stock returns

Honghai Yu
Xianfeng Hao
Yudong Wang
ResearchOpen Access07 Jul 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-16
Oleic acid restores the impaired antitumor immunity of γδ-T cells induced by palmitic acid

Yanmei Zhang
Zheng Xiang
Wenwei Tu
ResearchOpen Access03 Jul 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-17
Dominance of open burning signatures in PM_2.5 near coal plant should redefine pollutant priorities of India

Iravati Ray
Shoumick Mitra
Reshmi Das
ResearchOpen Access20 Nov 2024
npj Climate and Atmospheric Science

Volume: 7, P: 1-17
Exploring BCL2 regulation and upstream signaling transduction in venetoclax resistance in multiple myeloma: potential avenues for therapeutic intervention

Rodrigo Fonseca
Yuan Xiao Zhu
Rafael Fonseca
ResearchOpen Access05 Feb 2025
Blood Cancer Journal

Volume: 15, P: 1-12
Interfering with retrotransposition by two types of CRISPR effectors: Cas12a and Cas13a

Niubing Zhang
Xinyun Jing
Pei Hao
ResearchOpen Access19 May 2020
Cell Discovery

Volume: 6, P: 1-12
Machine learning-guided integration of fixed and mobile sensors for high resolution urban PM_2.5 mapping

Tianshuai Li
Xin Huang
Wenxing Wang
ResearchOpen Access10 Mar 2025
npj Climate and Atmospheric Science

Volume: 8, P: 1-9
Cloud cover and expected oil returns

Xianfeng Hao
Yudong Wang
ResearchOpen Access23 Sept 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-10
Excellent thermoelectric performance of Fe₂NbAl alloy induced by strong crystal anharmonicity and high band degeneracy

Xianfeng Ye
Jian Yu
Qingjie Zhang
ResearchOpen Access13 Aug 2024
npj Quantum Materials

Volume: 9, P: 1-10
Enhancing fresh-cut spinach preservation with carbon quantum dot-based composite coatings

Sijing Zhu
Linxuan Jin
Lingling Liu
ResearchOpen Access11 Jul 2025
Scientific Reports

Volume: 15, P: 1-12
The characterization, mechanism, predictability, and impacts of the unprecedented 2023 Southeast Asia heatwave

Yang Lyu
Jingyu Wang
Duc Tran Dung
ResearchOpen Access14 Oct 2024
npj Climate and Atmospheric Science

Volume: 7, P: 1-12
The discovery of a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1) for ischemic heart: synthesis, activity and target identification

Ying Wang
Yang Cao
Yi Zhun Zhu
ResearchOpen Access22 Jul 2016
Scientific Reports

Volume: 6, P: 1-10
Aortic smooth muscle TRPV4 channels regulate vasoconstriction in high salt-induced hypertension

Xin Wen
Yidi Peng
Qingyou Meng
Research02 Aug 2023
Hypertension Research

Volume: 46, P: 2356-2367
The synergistic antitumor effect of IL-6 neutralization with NVP-BEZ235 in hepatocellular carcinoma

Yao Wang
Xiaolong Miao
Weihua Gong
ResearchOpen Access14 Feb 2022
Cell Death & Disease

Volume: 13, P: 1-9
Function and evolution of Magnaporthe oryzae avirulence gene AvrPib responding to the rice blast resistance gene Pib

Shulin Zhang
Ling Wang
Qinghua Pan
ResearchOpen Access25 Jun 2015
Scientific Reports

Volume: 5, P: 1-10

Search

Autonomous artificial intelligence prescribing a drug to prevent severe acute graft-versus-host disease in HLA-haploidentical transplants

SL\((2,{\mathbb{C}})\) non-Abelian gauge fields in a photonic molecule array

Involvement of JNK-initiated p53 accumulation and phosphorylation of p53 in pseudolaric acid B induced cell death

Parkinson’s disease: spatiotemporal regulation and therapeutic prospects of TREM2-mediated microglial responses

Poking cells for efficient vector-free intracellular delivery

Influence of the inclination angles on the stress distribution in the bottom plate under the deep residual coal pillar

Targeting initial tumour–osteoclast spatiotemporal interaction to prevent bone metastasis

Nickel-catalysed selective migratory hydrothiolation of alkenes and alkynes with thiols

Massively parallel variant-to-function mapping determines functional regulatory variants of non-small cell lung cancer

Highly lethal genotype I and II recombinant African swine fever viruses detected in pigs

A deep learning-based model for screening and staging pneumoconiosis

Storing light near an exceptional point

A multicenter phase 2 trial of camrelizumab plus famitinib for women with recurrent or metastatic cervical squamous cell carcinoma

Molecular identification and quantification of defect sites in metal-organic frameworks with NMR probe molecules

Pseudolaric acid B induces apoptosis via activation of c-Jun N-terminal kinase and caspase-3 in HeLa cells

Porous membrane with high curvature, three-dimensional heat-resistance skeleton: a new and practical separator candidate for high safety lithium ion battery

Optimization of wavefront reconstruction accuracy for conjugate shift differential absolute testing

Evolution of the electronic structure in open-shell donor-acceptor organic semiconductors

Sequencing and de novo assembly of a near complete indica rice genome

A novel capsule-based self-recovery system with a chloride ion trigger

Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients

Eye in outer space: satellite imageries of container ports can predict world stock returns

Oleic acid restores the impaired antitumor immunity of γδ-T cells induced by palmitic acid

Dominance of open burning signatures in PM_2.5 near coal plant should redefine pollutant priorities of India

Exploring BCL2 regulation and upstream signaling transduction in venetoclax resistance in multiple myeloma: potential avenues for therapeutic intervention

Interfering with retrotransposition by two types of CRISPR effectors: Cas12a and Cas13a

Machine learning-guided integration of fixed and mobile sensors for high resolution urban PM_2.5 mapping

Cloud cover and expected oil returns

Excellent thermoelectric performance of Fe₂NbAl alloy induced by strong crystal anharmonicity and high band degeneracy

Enhancing fresh-cut spinach preservation with carbon quantum dot-based composite coatings

The characterization, mechanism, predictability, and impacts of the unprecedented 2023 Southeast Asia heatwave

The discovery of a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1) for ischemic heart: synthesis, activity and target identification

Aortic smooth muscle TRPV4 channels regulate vasoconstriction in high salt-induced hypertension

The synergistic antitumor effect of IL-6 neutralization with NVP-BEZ235 in hepatocellular carcinoma

Function and evolution of Magnaporthe oryzae avirulence gene AvrPib responding to the rice blast resistance gene Pib

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