The authors demonstrate that plasma exosomes from children with idiopathic short stature contain elevated hsa-miR-17-3p, that disrupts growth signaling and impairs cartilage cell proliferation. A capsaicin-rich diet in rats triggered gut inflammation, increased exosomal miR-17-3p and recapitulated features of idiopathic short stature.
- Yameng Wang
- Zhiwen Wu
- Jingyu Jia
