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Showing 1–6 of 6 results

Advanced filters: Author: Xinyan Qu Clear advanced filters

Igh nuclear speckle association promotes V(D)J recombination

Immunoglobulin heavy chain (IgH) diversity is shaped by locus positioning in 3D nuclear space. Here, the authors demonstrate that a highly transcribed VH gene drives Igh contact with nuclear speckles, boosting chromatin accessibility, facilitating V to DJ rearrangement and supporting allelic exclusion.

Saurabh Priyadarshi
Khalid H. Bhat
Amy L. Kenter
ResearchOpen Access20 Apr 2026
Nature Communications

P: 1-20
CDNFE suggests FNDC3B and NECTIN4 as drivers of precancer progression via PI3K/AKT EMT

Rui Qiao
Qingwei Zhang
Peiluan Li
ResearchOpen Access24 Apr 2026
npj Precision Oncology

P: 1-16
Protective effects of 20(R) ginsenoside Rg3 on DBP-induced reproductive injury in mice through Nrf2/ARE pathway

Huan Li
Hongyan Wang
Li Qu
ResearchOpen Access24 Nov 2025
Scientific Reports

Volume: 15, P: 1-9
Therapeutic targeting of endothelial calcium signaling accelerates the resolution of lung injury

Wan Ching Chan
Man Long Kwok
Yulia A. Komarova
ResearchOpen Access18 Nov 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-21
An Igh distal enhancer modulates antigen receptor diversity by determining locus conformation

Here the authors show enhancers in the Igh locus play a major role in configuring locus architecture and in V(D)J recombination, and identify a link between enhancer hub formation, locus contraction and cohesin-mediated loop extrusion.

Khalid H. Bhat
Saurabh Priyadarshi
Amy L. Kenter
ResearchOpen Access03 Mar 2023
Nature Communications

Volume: 14, P: 1-18
Adaptive variable channel heat dissipation control of ground control station under various work modes

Dexin Wang
Jiali Tao
Yujie Zeng
ResearchOpen Access15 Feb 2025
Scientific Reports

Volume: 15, P: 1-24