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Author Correction: Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment

Xuexian O. Yang
Pornpimon Angkasekwinai
Chen Dong
Amendments and Corrections03 Sept 2020
Nature Immunology

Volume: 21, P: 1467
Depletion of JunB increases adipocyte thermogenic capacity and ameliorates diet-induced insulin resistance

Zhang et al. show that in mice, an adipocyte population with high expression of the transcription factor JunB in the brown adipose tissue shows reduced thermogenic capacity. Depletion of JunB increases the fraction of adipocytes with high thermogenic capacity and ameliorates diet-induced insulin resistance.

Xing Zhang
Xiaofeng Ding
Meilian Liu
Research08 Jan 2024
Nature Metabolism

Volume: 6, P: 78-93
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

Heon Park
Zhaoxia Li
Chen Dong
Research02 Oct 2005
Nature Immunology

Volume: 6, P: 1133-1141
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

Interleukin (IL)-17 expressing helper T cells (T_H17) have recently been identified as a effector subset involved in tissue inflammation. In this paper, it is shown that the cytokine IL-21 is induced downstream of IL-6 by a STAT3 dependent mechanism and participates in inducing T_H17 cell differentiation in an autocrine and ROR-γ dependent manner

Roza Nurieva
Xuexian O. Yang
Chen Dong
Research20 Jun 2007
Nature

Volume: 448, P: 480-483
Catheter-integrated soft multilayer electronic arrays for multiplexed sensing and actuation during cardiac surgery

Soft multilayer electronic arrays on endocardial balloon catheters allow for multiplexed high-density spatiotemporal sensing and actuation, as shown in perfused ex vivo hearts.

Mengdi Han
Lin Chen
John A. Rogers
Research07 Sept 2020
Nature Biomedical Engineering

Volume: 4, P: 997-1009
Effect of lead zinc mineralization area on heavy metals accumulation and geochemical fractions of agricultural soils in Southwest China

Zhenglu Yu
Xuexian Li
Zhuo Chen
ResearchOpen Access01 Jun 2025
Scientific Reports

Volume: 15, P: 1-16
Requirement for the basic helix-loop-helix transcription factor Dec2 in initial T_H2 lineage commitment

The molecular mediators responsible for directing T helper type 2 (T_H2) differentiation remain incompletely defined. Dong and co-workers find that the transcription factor Dec2 promotes expression of the transcription factor JunB and is essential for the induction of T_H2 responses.

Xuexian O Yang
Pornpimon Angkasekwinai
Chen Dong
Research01 Nov 2009
Nature Immunology

Volume: 10, P: 1260-1266
The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation

SOCS proteins suppress cytokine signaling by inhibiting activation of STAT signal transducers. Dong and colleagues show that the SOCS protein CIS is induced by IL-4 to control T_H2 and T_H9 helper T cell differentiation.

Xuexian O Yang
Huiyuan Zhang
Chen Dong
Research02 Jun 2013
Nature Immunology

Volume: 14, P: 732-740
IL-23 signaling enhances Th2 polarization and regulates allergic airway inflammation

Juan Peng
Xuexian O Yang
Chen Dong
Research24 Nov 2009
Cell Research

Volume: 20, P: 62-71
Expression and regulation of IL-22 in the IL-17-producing CD4+ T lymphocytes

Yeonseok Chung
Xuexian Yang
Chen Dong
Research07 Nov 2006
Cell Research

Volume: 16, P: 902-907
The molecular and metabolic landscape of iron and ferroptosis in cardiovascular disease

Since the discovery of ferroptosis a decade ago, this iron-dependent form of regulated cell death has been implicated in the pathogenesis of cardiovascular disease. In this Review, Fudi Wang and colleagues discuss the link between the metabolic pathways of iron signalling and ferroptosis in the context of the cardiovascular system and describe the potential of ferroptosis inhibitors in the treatment of cardiovascular disease.

Xuexian Fang
Hossein Ardehali
Fudi Wang
Reviews04 Jul 2022
Nature Reviews Cardiology

Volume: 20, P: 7-23
NMN partially rescues cuproptosis by upregulating sirt2 to increase intracellular NADPH

Yingying Zhang
Shuting Qiu
Xiaohua Tan
ResearchOpen Access20 Aug 2024
Scientific Reports

Volume: 14, P: 1-10
Leptin Promotes Allergic Airway Inflammation through Targeting the Unfolded Protein Response Pathway

Handong Zheng
Dandan Wu
Xuexian O. Yang
ResearchOpen Access11 Jun 2018
Scientific Reports

Volume: 8, P: 1-12
Treg expression of CIS suppresses allergic airway inflammation through antagonizing an autonomous TH2 program

Handong Zheng
Xiang Wu
Xuexian O. Yang
Research28 Nov 2019
Mucosal Immunology

Volume: 13, P: 293-302
Functional Role of Cyclin-Dependent Kinase 5 in the Regulation of Melanogenesis and Epidermal Structure

Changsheng Dong
Shanshan Yang
Muren Herrid
ResearchOpen Access23 Oct 2017
Scientific Reports

Volume: 7, P: 1-12

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