Myoglobin (Mb) is the critical pathogenic factor for Rhabdomyolysis or Crush syndrome-related AKI (RM/CS-AKI). Here, the authors show that anti-Mb RabMAb injection blocking the passage of free Mb through the glomerular filtration barrier significantly rescues both homologous and heterologous RM/CS-AKI animal models.
- Xinyue Wang
- Ning Li
- Yanhua Gong
