Nature Search

A mass spectrometry-based strategy allows signature metabolite identification in tear fluid from people with diabetic cataracts

Here, the authors develop an integrated mass spectrometry-based strategy that allows metabolic biomarker discovery based on nanoliter-scale biofluids in seconds. Biomarkers of diabetic cataracts are detected in trace ocular fluids with high diagnostic performance revealed to have and anti-cataract activity.

Ziheng Qi
Miao Wang
Jingjing Wan
ResearchOpen Access21 Nov 2025
Nature Communications

Volume: 16, P: 1-16
Exploring the feedback limits of quantum dot lasers for isolator-free photonic integrated circuits

By accessing the coherence-collapse regime under strong on-chip feedback, quantum dot lasers demonstrate unprecedented robustness, supporting penalty-free operation and practical isolator-free photonic integrated circuits.

Ying Shi
Bozhang Dong
Yating Wan
ResearchOpen Access30 Jan 2026
Light: Science & Applications

Volume: 15, P: 1-12
Meet the winners of the 2024 Sony Women in Technology Award

Technology research is the driving force of the innovations that shape the world. Sony Group Corporation (Sony) and Nature partnered together to launch the Sony Women in Technology Award to recognize three outstanding early to mid-career researchers from the field of technology. Here, we interviewed the winners of the inaugural 2024 award on the inspirations behind their outstanding research.

Kiana Aran
Jiawen Li
Yating Wan
Reviews08 May 2025
Nature Reviews Electrical Engineering

Volume: 2, P: 297-301
Turnkey locking of quantum-dot lasers directly grown on Si

A quantum-dot laser directly grown on silicon that is scalable, low cost with an intrinsic linewidth of 16 Hz when subject to feedback from a low-quality-factor external cavity is reported.

Bozhang Dong
Yating Wan
John E. Bowers
ResearchOpen Access26 Apr 2024
Nature Photonics

Volume: 18, P: 669-676
Author Correction: Multikingdom and functional gut microbiota markers for autism spectrum disorder

Qi Su
Oscar W. H. Wong
Siew C. Ng
Amendments and Corrections04 Dec 2024
Nature Microbiology

Volume: 10, P: 600
Integrating silicon photonics with complementary metal–oxide–semiconductor technologies

Complementary metal–oxide–semiconductor-integrated silicon photonics offers a scalable path to high-bandwidth, low-energy optical interconnects for data centres and artificial intelligence/high-performance computing. This Review surveys device maturity, multimaterial and 3D integration, electronics co-design and packaging trends and maps a path towards comb-enabled dense wavelength-division multiplexing, petabit bandwidth and sub-picojoule per bit efficiency.

Yating Wan
William He
Haisheng Rong
Reviews07 Nov 2025
Nature Reviews Electrical Engineering

Volume: 3, P: 15-31
Ultrawide-bandwidth boron nitride photonic memristors

Photonic memristor arrays fabricated from hexagonal boron nitride/silicon heterostructures provide a scalable, silicon-compatible solution for artificial vision systems, featuring broad spectral reconfigurability and promising performance characteristics.

Maolin Chen
Yinchang Ma
Xixiang Zhang
Research31 Jul 2025
Nature Nanotechnology

Volume: 20, P: 1633-1640
Elevated TEFM expression promotes growth and metastasis through activation of ROS/ERK signaling in hepatocellular carcinoma

Lixin Wan
Yang Wang
Dengke Bao
ResearchOpen Access26 Mar 2021
Cell Death & Disease

Volume: 12, P: 1-12
Multikingdom and functional gut microbiota markers for autism spectrum disorder

Faecal metagenomes and machine learning reveal a panel of 31 multikingdom microbiome markers and microbiome functions that are associated with autism spectrum disorder in male and female children.

Qi Su
Oscar W. H. Wong
Siew C. Ng
Research08 Jul 2024
Nature Microbiology

Volume: 9, P: 2344-2355
A secreted effector with a dual role as a toxin and as a transcriptional factor

Bacteria can deliver toxic effector proteins into the cytosol of neighboring cells. Here, the authors show that Yersinia pseudotuberculosis secretes an effector that modulates gene expression in neighboring cells of the same species and inhibits the growth of other competitors.

Dandan Wang
Lingfang Zhu
Xihui Shen
ResearchOpen Access16 Dec 2022
Nature Communications

Volume: 13, P: 1-15
Heterologous immunization with inactivated vaccine followed by mRNA-booster elicits strong immunity against SARS-CoV-2 Omicron variant

Emerging SARS-CoV-2 variants of concern (VOCs) raises concerns regarding vaccine efficacy. Here, the authors evaluate the neutralizing antibody, and cellular response elicited following inactivated vaccine immunization, and mRNA booster, against the Omicron variant.

Fanglei Zuo
Hassan Abolhassani
Qiang Pan-Hammarström
ResearchOpen Access13 May 2022
Nature Communications

Volume: 13, P: 1-8
Electrically pumped quantum-dot lasers grown on 300 mm patterned Si photonic wafers

Chen Shang
Kaiyin Feng
John E. Bowers
ResearchOpen Access14 Oct 2022
Light: Science & Applications

Volume: 11, P: 1-8
Linewidth narrowing in self-injection-locked on-chip lasers

Investigation of the spectral narrowing physics of self-injection-locked on-chip lasers to Hz-level linewidth using a composite-cavity structure. Heterogeneously integrated III–V/SiN lasers operating with quantum-dot and quantum-well active regions are analyzed.

Emad Alkhazraji
Weng W. Chow
Yating Wan
ResearchOpen Access28 Jun 2023
Light: Science & Applications

Volume: 12, P: 1-10
Food, cooking and potteries in the Neolithic Mijiaya site, Guanzhong area, North China, revealed by multidisciplinary approach

Yating Qu
Junxiao Zhu
Longlong Zhou
ResearchOpen Access17 May 2023
Heritage Science

Volume: 11, P: 1-13
Light People: Prof. Kei May Lau, newly elected US NAE member in Hong Kong, talks about future of photonics and women in science

Yating Wan
Chenzi Guo
Comments & OpinionOpen Access11 Mar 2024
Light: Science & Applications

Volume: 13, P: 1-7
Synthesis of Cu_xO/Ag nanoparticles on exfoliated graphene: application for enhanced electrochemical detection of H₂O₂ in milk

Jie Song
Yating Wan
Yi Liu
ResearchOpen Access24 Apr 2023
Scientific Reports

Volume: 13, P: 1-12
Autocrine pro-legumain promotes breast cancer metastasis via binding to integrin αvβ3

Cui Liu
JunLei Wang
JianFeng Chen
Research19 Jul 2022
Oncogene

Volume: 41, P: 4091-4103
JOSD1 inhibits mitochondrial apoptotic signalling to drive acquired chemoresistance in gynaecological cancer by stabilizing MCL1

Xiaowei Wu
Qingyu Luo
Zhihua Liu
Research01 May 2019
Cell Death & Differentiation

Volume: 27, P: 55-70
A peptide N-terminal protection strategy for comprehensive glycoproteome analysis using hydrazide chemistry based method

Junfeng Huang
Hongqiang Qin
Hanfa Zou
ResearchOpen Access11 May 2015
Scientific Reports

Volume: 5, P: 1-15
Light People: Prof. Daoxin Dai, Dr. Patrick Lo, and Prof. Yikai Su—innovators in silicon photonics

Yating Wan
Chenzi Guo
Comments & OpinionOpen Access11 Oct 2024
Light: Science & Applications

Volume: 13, P: 1-6
Retrospective study of the immunogenicity and safety of the CoronaVac SARS-CoV-2 vaccine in people with underlying medical conditions

Li et al. evaluate the immunogenicity and safety of the CoronaVac inactivated COVID-19 vaccine in elderly patients with underlying medical conditions in China. Most patients show comparable neutralizing antibody and SARS-CoV-2-specific T cell responses to healthy controls, and no serious adverse effects are seen.

Chunmei Li
Hanfang Bi
Liang Zhang
ResearchOpen Access25 Nov 2022
Communications Medicine

Volume: 2, P: 1-11
Light People: Prof. John Bowers spoke about silicon photonics

Chenzi Guo
Yating Wan
Comments & OpinionOpen Access09 Dec 2022
Light: Science & Applications

Volume: 11, P: 1-6
Light people: Prof. Evelyn Hu’s adventure: from semiconductors to quantum – from industry to academia

Yating Wan
Chenzi Guo
Comments & OpinionOpen Access26 Jun 2023
Light: Science & Applications

Volume: 12, P: 1-8
Long-term and effective neutralization against omicron sublineages elicited by four platform COVID-19 vaccines as a booster dose

Yuemiao Zhang
Meng-Ting Luo
Lihong Zhang
CorrespondenceOpen Access08 Feb 2023
Cell Discovery

Volume: 9, P: 1-4

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