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Advanced filters: Author: Yen-Chu Lin Clear advanced filters

Engineering an autonomous VH domain to modulate intracellular pathways and to interrogate the eIF4F complex

Approaches have been devised to increase the discovery rate of intrabodies but often these yield results that aren’t functional in cells. Here the authors engineer and optimise an autonomous and disulphide-free human VH domain for intracellular expression, and they identify several VH domain binders against eIF4E.

Yuri Frosi
Yen-Chu Lin
Christopher J. Brown
ResearchOpen Access18 Aug 2022
Nature Communications

Volume: 13, P: 1-22
An observational study on salivary conductivity for fluid status assessment and clinical relevance in acute ischemic stroke during intravenous fluid hydration

Chun-Hao Chen
An-Ting Lee
Yen-Chu Huang
ResearchOpen Access18 Dec 2023
Scientific Reports

Volume: 13, P: 1-8
Thirst neurons anticipate the homeostatic consequences of eating and drinking

Feedback from the oral cavity to thirst-promoting neurons in the subfornical organ (SFO) during eating and drinking is integrated with information about blood composition, providing a prediction of how oral consumption will affect fluid balance and leading to changes in behaviour.

Christopher A. Zimmerman
Yen-Chu Lin
Zachary A. Knight
Research03 Aug 2016
Nature

Volume: 537, P: 680-684
Quantum simulation of preferred tautomeric state prediction

Yu Shee
Tzu-Lan Yeh
Min-Hsiu Hsieh
ResearchOpen Access16 Oct 2023
npj Quantum Information

Volume: 9, P: 1-12

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