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Showing 1–19 of 19 results
Advanced filters: Author: Yiliang Ding Clear advanced filters
  • The authors find that O-GalNAc transferase 2 (GALNT2) restricts viral infection, probably through the regulation of the proteolytic processing of viral glycoproteins via its O-linked glycosylation activity, impairing virus–cell fusion.

    • Wei Ran
    • Jinghong Yang
    • Jincun Zhao
    ResearchOpen Access
    Nature Microbiology
    Volume: 11, P: 256-270
  • Approaches are needed to explore regulatory RNA motifs in plants. An interpretable RNA foundation model is developed, trained on thousands of plant transcriptomes, which achieves superior performance in plant RNA biology tasks and enables the discovery of functional RNA sequence and structure motifs across transcriptomes.

    • Haopeng Yu
    • Heng Yang
    • Ke Li
    ResearchOpen Access
    Nature Machine Intelligence
    Volume: 6, P: 1616-1625
  • This study shows that mRNA decay in durum wheat is affected by 3’ UTR structures and domestication-selected single-nucleotide variations, highlighting the importance of non-coding regions in gene expression and the potential for crop enhancement.

    • Haidan Wu
    • Haopeng Yu
    • Huakun Zhang
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14
  • A new artificial intelligence model, DeepSeek-R1, is introduced, demonstrating that the reasoning abilities of large language models can be incentivized through pure reinforcement learning, removing the need for human-annotated demonstrations.

    • Daya Guo
    • Dejian Yang
    • Zhen Zhang
    ResearchOpen Access
    Nature
    Volume: 645, P: 633-638
  • The structures of single COOLAIR RNA isoforms change in abundance and shape in response to external conditions; structural mutation of these isoforms altered FLC expression and flowering time, consistent with a regulatory role of the COOLAIR structure in FLC transcription.

    • Minglei Yang
    • Pan Zhu
    • Yiliang Ding
    ResearchOpen Access
    Nature
    Volume: 609, P: 394-399
  • During evolution, plants have adapted to habitats with distinct temperature ranges. In this study, scientists report that a specific RNA structure motif, RNA G-quadruplex (RG4) is enriched across genomes of plant species growing in colder climates.

    • Xiaofei Yang
    • Haopeng Yu
    • Yiliang Ding
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-9
  • RNA is central to many cellular functions, but in vivo structures of most RNAs are unknown. Here Kwok et al. present a universally applicable method, DMS/SHAPE-LMPCR, to identify structures of low-abundance transcripts in living cells, which reveals important features that are uniquely present in vivo.

    • Chun Kit Kwok
    • Yiliang Ding
    • Philip C Bevilacqua
    Research
    Nature Communications
    Volume: 4, P: 1-12
  • The emergence of vascular plants requires tightly regulated mechanisms to control the photosynthate transporting system. For phloem establishment and carbon allocation to sink tissues, a novel translational regulatory network involving a zinc-finger protein and RNA G-quadruplex is now revealed for the first time.

    • Yiliang Ding
    • Chun Kit Kwok
    News & Views
    Nature Plants
    Volume: 4, P: 325-326
  • Recently developed RNA structure profiling methods are transforming our understanding of static and dynamic facets of RNA structures at single-cell and single-molecule resolution. These data have revealed new roles for structures in RNA biogenesis and function, and guide drug design against viral RNAs and for treatment of genetic diseases.

    • Xinang Cao
    • Yueying Zhang
    • Yue Wan
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 25, P: 784-801
  • Improving photosynthetic efficiency is crucial for CO>sub<2 > /sub < -based biomanufacturing and agriculture. Here, biomass-derived carbon dots in biohybrids are shown to enhance natural photosynthesis by converting solar irradiation to red light and supplying electrons to the photosynthetic electron transfer chain.

    • Wenbo Cheng
    • Xueyun Wang
    • Xiang Gao
    ResearchOpen Access
    Communications Materials
    Volume: 6, P: 1-13
  • Wang et al. use a Natural Language Processing approach to detect suicide-circumstance annotation inconsistencies in death investigation notes. They identify possible label errors, show the effectiveness of identifying and rectifying possible label errors, and propose a coding consistency improvement solution.

    • Song Wang
    • Yiliang Zhou
    • Yifan Peng
    ResearchOpen Access
    Communications Medicine
    Volume: 4, P: 1-13