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Showing 1–5 of 5 results
Advanced filters: Author: Yonglong Dang Clear advanced filters

  • A tri-omic atlas of the mouse brain from postnatal day 0 to P21 reveals that layer-specific projection neurons have a role in coordinating axonogenesis and myelination.

    • Di Zhang
    • Leslie A. Rubio Rodríguez-Kirby
    • Rong Fan
    ResearchOpen Access
    Nature
    Volume: 647, P: 213-227

  • Glioblastoma (GBM) heterogeneity might arise because of the activation of various gene core regulatory circuitries (CRCs). A new study highlights the central role of HOXB3 in GBM CRCs and how peptide-mediated perturbation of HOXB3-related CRCs in GBM holds potential as treatment for a subset of patients.

    • Yonglong Dang
    • Yuk Kit Lor
    • Gonçalo Castelo-Branco
    News & Views
    Nature Cell Biology
    Volume: 27, P: 1600-1602

  • The epigenetic regulation of glioblastoma stem cell (GSC) function remains poorly understood. Here, the authors compare the chromatin accessibility landscape of GSC cultures from mice and patients and suggest that the epigenome of GSCs is cell lineage-regulated and could predict patient survival.

    • Xi Lu
    • Naga Prathyusha Maturi
    • Xingqi Chen
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16

  • The role of focal amplifications and extrachromosomal DNA (ecDNA) is unknown in gastric cardia adenocarcinoma (GCA). Here, the authors identify frequent focal amplifications and ecDNAs in Chinese GCA patient samples, as well as the potential associations of these alterations with prognosis and dietary habits.

    • Xue-Ke Zhao
    • Pengwei Xing
    • Li-Dong Wang
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14