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Advanced filters: Author: Yongxia Niu Clear advanced filters

Adipocyte FMO3-derived TMAO induces WAT dysfunction and metabolic disorders by promoting inflammasome activation in ageing

White adipose tissue (WAT) dysfunction leads to ageing-related metabolic disorders. Here, the authors show that the FMO3-TMAO axis in adipocytes induces senescence and inflammation in WAT microenvironment via NLRP3 inflammasome, leading to systemic glucose, lipid, and energy dysregulation in ageing

Thashma Ganapathy
Juntao Yuan
Kenneth King-yip Cheng
ResearchOpen Access06 Oct 2025
Nature Communications

Volume: 16, P: 1-23
Elevated TEFM expression promotes growth and metastasis through activation of ROS/ERK signaling in hepatocellular carcinoma

Lixin Wan
Yang Wang
Dengke Bao
ResearchOpen Access26 Mar 2021
Cell Death & Disease

Volume: 12, P: 1-12
Study on the mechanical properties and microscopic mechanism of xanthan gum improved red clay

Fan Yang
Zhixia Zhao
Hongji Deng
ResearchOpen Access29 Aug 2025
Scientific Reports

Volume: 15, P: 1-15
Gene therapy prevents onset of mitochondrial cardiomyopathy in neonatal mice with Ndufs6 deficiency

Xiaoxian Zhang
Li Huang
Qizhou Lian
ResearchOpen Access22 May 2025
Cell Death Discovery

Volume: 11, P: 1-15
Chromosome-scale assembly of the Dendrobium chrysotoxum genome enhances the understanding of orchid evolution

Yongxia Zhang
Guo-Qiang Zhang
Zhong-Jian Liu
ResearchOpen Access01 Sept 2021
Horticulture Research

Volume: 8, P: 1-14

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