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Showing 1–50 of 125 results

Advanced filters: Author: Yoshiki Tanaka Clear advanced filters

Real-time capture of domain movements during copper amine oxidase catalysis by mix-and-inject serial crystallography

Protein motion is essential for biological processes like enzyme function. Here the authors report the time-resolved protein structures captured during catalysis of copper amine oxidase using mix-and-inject serial femtosecond X-ray crystallography.

Takeshi Murakawa
Mamoru Suzuki
Toshihide Okajima
ResearchOpen Access18 Dec 2025
Nature Communications

Volume: 16, P: 1-11
Promotion of early osteoclastogenesis and B lymphopoiesis in the bone marrow of transgenic rats with the env-pX gene of human T-cell lymphotropic virus type I

Hidetoshi Yamazaki
Takahiro Kunisada
Takashi Yoshiki
Research09 Dec 1998
Oncogene

Volume: 17, P: 2955-2960
Artificial intelligence pioneers the double-strangeness factory

Unambiguous identification of double-strangeness hypernuclei is a challenging task in nuclear physics. Here, the AUs demonstrate identification of 13ΛΛ-B hypernuclei from an AI pipeline applied to the analysis of nuclear emulsion data from the JPARC-E07 experiment.

Yan He
Takehiko R. Saito
Hongfei Zhang
ResearchOpen Access22 Nov 2025
Nature Communications

Volume: 16, P: 1-9
Structural basis of sugar-recognizing ubiquitin ligase

Tsunehiro Mizushima
Takeshi Hirao
Keiji Tanaka
Research29 Feb 2004
Nature Structural & Molecular Biology

Volume: 11, P: 365-370
Improving Proton Relaxivity of Dendritic MRI Contrast Agents by Rigid Silsesquioxane Core

Kazuo Tanaka
Narufumi Kitamura
Yoshiki Chujo
Research12 Feb 2009
Polymer Journal

Volume: 41, P: 287-292
A post-starburst pathway for the formation of massive galaxies and black holes at z > 6

Two high-redshift post-starburst galaxies are in the process of quenching, although their quasars remain active, indicating the complex co-evolution between black hole activity and star formation.

Masafusa Onoue
Xuheng Ding
Haowen Zhang
Research11 Aug 2025
Nature Astronomy

Volume: 9, P: 1541-1552
Co-expression of Fas and Fas-ligand on the surface of influenza virus-infected cells

Ippei Fujimoto
Takenori Takizawa
Yoshinobu Nakanishi
Research15 May 1998
Cell Death & Differentiation

Volume: 5, P: 426-431
pH Responsive Aggregation of Imidazolium Cations-Modified Gold Nanoparticles with Poly(acrylic acid) in Aqueous Solution

Kensuke Naka
Hiroyuki Tanaka
Yoshiki Chujo
Research07 Sept 2007
Polymer Journal

Volume: 39, P: 1122-1127
Stereoregular Oligomers of Methyl Methacrylate: X-Ray Crystal Structure Analysis and ¹H NMR Spectrum of the Trimer

Koichi Ute
Tohru Nishimura
Koichi Hatada
Research01 Mar 1989
Polymer Journal

Volume: 21, P: 231-240
Spinocerebellar ataxia 1 (SCA1) in the Japanese: Analysis of CAG trinucleitide repeat expansion and instability of the repeat for paternal transmission

Yoshihiro Suzuki
Hidenao Sasaki
Takeshi Hamada
Research01 Mar 1995
Japanese journal of human genetics

Volume: 40, P: 131-143
Single-dose DSS-induced inflammation enhances colorectal tumorigenesis in APC and KRAS mutant mice

Kazuki Ishibashi
Yuji Urabe
Shiro Oka
ResearchOpen Access24 Nov 2025
Scientific Reports

Volume: 15, P: 1-16
Crystal Structure of Methyl Methacrylate Dimer. Revised meso/racemo Assignment for the Dimer

Tamaki Nakano
Koichi Ute
Koichi Hatada
Research01 Nov 1989
Polymer Journal

Volume: 21, P: 935-939
Thermoresponsive Organic–Inorganic Polymer Hybrids from Poly(N-isopropylacrylamide)

Yusuke Imai
Naoki Yoshida
Yoshiki Chujo
Research01 Mar 1999
Polymer Journal

Volume: 31, P: 258-262
Erratum: Acetate-mediated novel survival strategy against drought in plants

Jong-Myong Kim
Taiko Kim To
Motoaki Seki
Amendments and Corrections17 Jul 2017
Nature Plants

Volume: 3, P: 1
Integration of polygenic risk score with measured blood pressure reveals hidden risks of cardiovascular disease mortality: A Japanese prospective cohort study

Hiroshi Okumiyama
Ryosuke Fujii
Chihaya Koriyama
Research24 Dec 2025
Hypertension Research

P: 1-11
Grease matrix as a versatile carrier of proteins for serial crystallography

Serial femtosecond crystallography experiments with diverse protein microcrystal suspensions are facilitated using a grease matrix as a carrier medium for sample injection.

Michihiro Sugahara
Eiichi Mizohata
So Iwata
Research10 Nov 2014
Nature Methods

Volume: 12, P: 61-63
Oxygen-evolving photosystem II structures during S₁–S₂–S₃ transitions

Serial femtosecond crystallography reveals the structural dynamics of photosystem II during the S-state transitions that produce dioxygen, providing insight into electron transfer, water insertion, proton release and O–O bond formation on sub-microsecond timescales.

Hongjie Li
Yoshiki Nakajima
Jian-Ren Shen
ResearchOpen Access31 Jan 2024
Nature

Volume: 626, P: 670-677
Assessment of Epidermal Barrier Function by Photoacoustic Spectrometry in Relation to Its Importance in the Pathogenesis of Atopic Dermatitis

Maki Hata
Yoshiki Tokura
Genji Imokawa
Research01 Nov 2002
Laboratory Investigation

Volume: 82, P: 1451-1461
π-Conjugated Organoboron Polymers via the Vacant p-Orbital of the Boron Atom

Noriyoshi Matsumi
Yoshiki Chujo
Reviews26 Dec 2007
Polymer Journal

Volume: 40, P: 77-89
Association between parental decisions regarding abortion and severity of fetal heart disease

Masahiro Nakao
Masanari Kuwabara
Tomoaki Ikeda
ResearchOpen Access01 Jul 2024
Scientific Reports

Volume: 14, P: 1-8
Observational study of rebiopsy in EGFR-TKI-resistant patients with EGFR mutation-positive advanced NSCLC

Kenichi Koyama
Satoru Miura
Toshiaki Kikuchi
ResearchOpen Access16 Apr 2022
Scientific Reports

Volume: 12, P: 1-8
Author Correction: Structural basis for the drug extrusion mechanism by a MATE multidrug transporter

Yoshiki Tanaka
Christopher J. Hipolito
Osamu Nureki
Amendments and Corrections30 Jan 2020
Nature

Volume: 578, P: E19
Factors associated with cam deformity in Japanese local residents

Koichi Tomomatsu
Takaya Taniguchi
Hiroshi Yamada
ResearchOpen Access18 Jan 2024
Scientific Reports

Volume: 14, P: 1-7
Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily gene

Hidetoshi Date
Osamu Onodera
Shoji Tsuji
Research01 Oct 2001
Nature Genetics

Volume: 29, P: 184-188
Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon merolae 10D

Motomichi Matsuzaki
Osami Misumi
Tsuneyoshi Kuroiwa
ResearchOpen Access08 Apr 2004
Nature

Volume: 428, P: 653-657
High-temperature ²⁰⁵Tl decay clarifies ²⁰⁵Pb dating in early Solar System

Measurement of the bound-state β⁻ decay of ²⁰⁵Tl⁸¹⁺ gives a new, longer half-life, allowing for the calculation of accurate stellar ²⁰⁵Pb yields and the isolation time of the early Solar System.

Guy Leckenby
Ragandeep Singh Sidhu
Jianwei Zhao
ResearchOpen Access13 Nov 2024
Nature

Volume: 635, P: 321-326
Short disordered protein segment regulates cross-species transmission of a yeast prion

The side chain interaction within the short disordered segment of yeast prion protein Sup35 could affect the conformation of the main chain, alter the transmission barrier between species and regulate its cross-seeding activity.

Toshinobu Shida
Yuji O. Kamatari
Motomasa Tanaka
Research13 Apr 2020
Nature Chemical Biology

Volume: 16, P: 756-765
Association between acetabular dysplasia and sagittal spino-pelvic alignment in a population-based cohort in Japan

Teiji Harada
Hiroshi Hashizume
Hiroshi Yamada
ResearchOpen Access25 Jul 2022
Scientific Reports

Volume: 12, P: 1-7
Chiral symmetry restoration at high matter density observed in pionic atoms

In quantum chromodynamics, the condensation of quark–antiquark pairs breaks the chiral symmetry of vacuum. Experiments with pionic tin atoms demonstrate that the symmetry is partially restored at high densities.

Takahiro Nishi
Kenta Itahashi
Koichi Yoshida
Research23 Mar 2023
Nature Physics

Volume: 19, P: 788-793
Crystal structure of the MgtE Mg²⁺ transporter

The crystal structure of a member of the MgtE family of Mg²⁺ transporters at 3.5Å resolution, and the structure of just the cytoplasmic domain in the presence and absence of Mg²⁺ is described. An elegant gating mechanism involving negative feedback by Mg²⁺ is also proposed.

Motoyuki Hattori
Yoshiki Tanaka
Osamu Nureki
Research15 Aug 2007
Nature

Volume: 448, P: 1072-1075
Direct interactions between NEDD8 and ubiquitin E2 conjugating enzymes upregulate cullin-based E3 ligase activity

Eri Sakata
Yoshiki Yamaguchi
Koichi Kato
Research07 Jan 2007
Nature Structural & Molecular Biology

Volume: 14, P: 167-168
Relationship of sagittal spinal alignment with low back pain and physical performance in the general population

Kazuhiro Hira
Keiji Nagata
Hiroshi Yamada
ResearchOpen Access18 Oct 2021
Scientific Reports

Volume: 11, P: 1-8
Synthesis of Bipyridyl-Branched Polyoxazoline and Its Gelation by Means of Metal Coordination

Yoshiki Chujo
Kazuki Sada
Takeo Saegusa
Research01 Jun 1993
Polymer Journal

Volume: 25, P: 599-608
DNA metabarcoding focusing on the plankton community: an effective approach to reconstruct the paleo-environment

Yasuhide Nakamura
Eri Ogiso-Tanaka
Yoshiki Saito
ResearchOpen Access08 Dec 2023
Scientific Reports

Volume: 13, P: 1-8
Synthesis of PAMAM Dendrimers Possessing [2.2]Paracyclophane on Their Surface

Yasuhiro Morisaki
Yoshiyuki Shiotani
Yoshiki Chujo
Research02 Jul 2008
Polymer Journal

Volume: 40, P: 779-783
Independent Determinants of Second Derivative of the Finger Photoplethysmogram among Various Cardiovascular Risk Factors in Middle-Aged Men

Toshiaki Otsuka
Tomoyuki Kawada
Yoshiki Kusama
Research01 Dec 2007
Hypertension Research

Volume: 30, P: 1211-1218
Effect of Molecular Weights of Poly(acrylic acid) on Crystallization of Calcium Carbonate by the Delayed Addition Method

Shu-Chen Huang
Kensuke Naka
Yoshiki Chujo
Research18 Dec 2007
Polymer Journal

Volume: 40, P: 154-162
Liquid-Crystalline Polymer Gels VI. Preparation and Swelling Behavior of Cross-Linked Hydrogels of Poly(L-glutamic acid) Possessing Cholesteric Order

Yoshiki Matsuoka
Ryoichi Kishi
Masahiko Sisido
Research01 Sept 1993
Polymer Journal

Volume: 25, P: 919-927
Intravenous nicardipine for Japanese patients with acute intracerebral hemorrhage: an individual participant data analysis

Kazunori Toyoda
Sohei Yoshimura
Kazuo Minematsu
ResearchOpen Access13 Oct 2022
Hypertension Research

Volume: 46, P: 75-83
Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser

A genetically encoded phototrigger based on a xanthone amino acid can expand the scope of time-resolved serial femtosecond crystallography beyond naturally photoactive proteins. This approach has been used to uncover metastable reaction intermediates that occur prior to C–H bond activation in a human liver fatty-acid-binding protein mutant.

Xiaohong Liu
Pengcheng Liu
Jiangyun Wang
Research18 Jul 2022
Nature Chemistry

Volume: 14, P: 1054-1060
VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid–liquid phase separation

Heart fibrosis involves a feedback loop where stiffening increases fibrosis-related gene expression in myofibroblasts. Here authors reveal the mechanosensitive nuclear translocation of VGLL3, where it phase separates and promotes collagen production, and show that its knock-out is protective after myocardial infarction.

Yuma Horii
Shoichi Matsuda
Michio Nakaya
ResearchOpen Access08 Feb 2023
Nature Communications

Volume: 14, P: 1-19
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
Prevalence and associated factors of pistol grip deformity in Japanese local residents

Takaya Taniguchi
Teiji Harada
Noriko Yoshimura
ResearchOpen Access16 Mar 2021
Scientific Reports

Volume: 11, P: 1-8
POSS ionic liquid crystals

The thermotropic ionic liquid crystal with the wide temperature range of the liquid crystal phase is reported using polyhedral oligomeric silsesquioxane. We found the liquid crystal phase of the POSS-tethered ion salts can be maintained until the pyrolysis occurs.

Kazuo Tanaka
Fumiyasu Ishiguro
Yoshiki Chujo
ResearchOpen Access17 Apr 2015
NPG Asia Materials

Volume: 7, P: e174
Electronic chirality inversion of lanthanide complex induced by achiral molecules

Satoshi Wada
Yuichi Kitagawa
Yasuchika Hasegawa
ResearchOpen Access06 Nov 2018
Scientific Reports

Volume: 8, P: 1-8
Plasma-activated medium promotes autophagic cell death along with alteration of the mTOR pathway

Nobuhisa Yoshikawa
Wenting Liu
Hiroaki Kajiyama
ResearchOpen Access31 Jan 2020
Scientific Reports

Volume: 10, P: 1-8
Chloroplast nucleoids as a transformable network revealed by live imaging with a microfluidic device

Yoshitaka Kamimura and colleagues combine live-imaging technology with microfluidics to examine chloroplast DNA organization in nucleoids. They find that these structures form a network structure in dividing chloroplasts, and propose a mechanism for their inheritance in organelle replication.

Yoshitaka Kamimura
Hitomi Tanaka
Yoshiki Nishimura
ResearchOpen Access17 May 2018
Communications Biology

Volume: 1, P: 1-7
Crystal structure of Escherichia coli YidC, a membrane protein chaperone and insertase

Kaoru Kumazaki
Toshiki Kishimoto
Osamu Nureki
ResearchOpen Access03 Dec 2014
Scientific Reports

Volume: 4, P: 1-6
Three Novel PHEX Gene Mutations in Japanese Patients with X-Linked Hypophosphatemic Rickets

Kohei Sato
Toshihiro Tajima
Kenji Fujieda
Research01 Oct 2000
Pediatric Research

Volume: 48, P: 536-540
Single injection of sustained-release prostacyclin analog ONO-1301-MS ameliorates hypoxic toxicity in the murine model of amyotrophic lateral sclerosis

Satoru Tada
Tatsusada Okuno
Hideki Mochizuki
ResearchOpen Access27 Mar 2019
Scientific Reports

Volume: 9, P: 1-9

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