Nature Search

Homoharringtonine exhibits senotherapeutic activity that mitigates diet- and age-associated obesity and insulin resistance and extends lifespan in mice

This study identifies an FDA-approved leukemia drug, Homoharringtonine, that can eliminate aged fat cells, improve metabolic health, reduce inflammation and extend lifespan in mice, revealing a potential approach to treat age- and obesity-related metabolic disease.

Eok-Cheon Kim
Han-Byul Jung
So-Young Park
ResearchOpen Access31 Mar 2026
Nature Communications

Volume: 17, P: 1-26
Longitudinal parametric response mapping on CT in assessing functional small airway disease and emphysema in COPD

Taeyun Kim
Youlim Kim
Hye Yun Park
ResearchOpen Access24 Oct 2025
Scientific Reports

Volume: 15, P: 1-8
Accessible homeostatic gastric organoids reveal secondary cell type-specific host-pathogen interactions in Helicobacter pylori infections

Current knowledge of the mechanisms that underly Helicobacter pylori (H. pylori) infections remains limited. Here, the authors present an in vitro gastric model that combines structural complexity with experimental accessibility, enabling improved research into H. pylori-induced pathogenesis.

Moritz Hofer
Youlim Kim
Matthias P. Lutolf
ResearchOpen Access20 Mar 2025
Nature Communications

Volume: 16, P: 1-9
MYADM binds human parechovirus 1 and is essential for viral entry

Host factors required for parechovirus entry are not well understood. Here, the authors identify MYADM as an essential host entry factor that directly binds human parechovirus 1 and that is required for PeV-A infection in cell lines and human gastrointestinal epithelial organoids.

Wenjie Qiao
Christopher M. Richards
Jan E. Carette
ResearchOpen Access24 Apr 2024
Nature Communications

Volume: 15, P: 1-14
Enhancing the electrical properties of graphite nanoflake through gamma-ray irradiation

Anh Tuan Nguyen
Youlim Lee
Woochul Lee
ResearchOpen Access01 Sept 2022
Scientific Reports

Volume: 12, P: 1-7
Predicting severe outcomes using national early warning score (NEWS) in patients identified by a rapid response system: a retrospective cohort study

Sang Hyuk Kim
Hye Suk Choi
Youlim Kim
ResearchOpen Access09 Sept 2021
Scientific Reports

Volume: 11, P: 1-8
Low levels of serum albumin and blood basophils as 10-year mortality predictors in a nationwide Korean COPD cohort

Hye Jung Park
Yeseul Song
Min Kwang Byun
ResearchOpen Access16 Dec 2025
Scientific Reports

Volume: 15, P: 1-11
CD9 induces cellular senescence and aggravates atherosclerotic plaque formation

Jung Hee Cho
Eok-Cheon Kim
Jae-Ryong Kim
Research28 Apr 2020
Cell Death & Differentiation

Volume: 27, P: 2681-2696
Clinical characteristics of chronic obstructive pulmonary disease patients with superoptimal peak inspiratory flow rate

Taeyun Kim
Ji-Yong Moon
Seung Won Ra
ResearchOpen Access03 Jul 2024
Scientific Reports

Volume: 14, P: 1-8
Increased mortality in patients with non cystic fibrosis bronchiectasis with respiratory comorbidities

Hayoung Choi
Bumhee Yang
Hyun Lee
ResearchOpen Access29 Mar 2021
Scientific Reports

Volume: 11, P: 1-9
Mdm1 ablation results in retinal degeneration by specific intraflagellar transport defects of photoreceptor cells

Youlim Son
Soo-Jin Kim
Jae-Ryong Kim
ResearchOpen Access28 Sept 2022
Cell Death & Disease

Volume: 13, P: 1-12
Mitochondrial glutamine metabolism regulates sensitivity of cancer cells after chemotherapy via amphiregulin

Sunsook Hwang
Seungyeon Yang
Seung Min Jeong
ResearchOpen Access20 Dec 2021
Cell Death Discovery

Volume: 7, P: 1-11
RNA binding protein HuD contributes to β-cell dysfunction by impairing mitochondria dynamics

Youlim Hong
Hyosun Tak
Eun Kyung Lee
Research28 Oct 2019
Cell Death & Differentiation

Volume: 27, P: 1633-1643
RNA binding protein HuD mediates the crosstalk between β cells and islet endothelial cells by the regulation of Endostatin and Serpin E1 expression

Myeongwoo Jung
Seungyeon Ryu
Eun Kyung Lee
ResearchOpen Access05 Dec 2022
Cell Death & Disease

Volume: 13, P: 1-11
Increased hospitalizations and economic burden in COPD with bronchiectasis: a nationwide representative study

Youlim Kim
Kyungjoo Kim
Seung Won Ra
ResearchOpen Access09 Mar 2022
Scientific Reports

Volume: 12, P: 1-8
The miR-30-5p/TIA-1 axis directs cellular senescence by regulating mitochondrial dynamics

Hyosun Tak
Seongho Cha
Eun Kyung Lee
ResearchOpen Access10 Jun 2024
Cell Death & Disease

Volume: 15, P: 1-11
Comparison of pneumonia incidence between long-acting muscarinic antagonist and inhaled corticosteroid plus long-acting beta agonist in patients with COPD

Eung Gu Lee
Youlim Kim
Chin Kook Rhee
ResearchOpen Access20 May 2023
Scientific Reports

Volume: 13, P: 1-12

Search

Homoharringtonine exhibits senotherapeutic activity that mitigates diet- and age-associated obesity and insulin resistance and extends lifespan in mice

Longitudinal parametric response mapping on CT in assessing functional small airway disease and emphysema in COPD

Accessible homeostatic gastric organoids reveal secondary cell type-specific host-pathogen interactions in Helicobacter pylori infections

MYADM binds human parechovirus 1 and is essential for viral entry

Enhancing the electrical properties of graphite nanoflake through gamma-ray irradiation

Predicting severe outcomes using national early warning score (NEWS) in patients identified by a rapid response system: a retrospective cohort study

Low levels of serum albumin and blood basophils as 10-year mortality predictors in a nationwide Korean COPD cohort

CD9 induces cellular senescence and aggravates atherosclerotic plaque formation

Clinical characteristics of chronic obstructive pulmonary disease patients with superoptimal peak inspiratory flow rate

Increased mortality in patients with non cystic fibrosis bronchiectasis with respiratory comorbidities

Mdm1 ablation results in retinal degeneration by specific intraflagellar transport defects of photoreceptor cells

Mitochondrial glutamine metabolism regulates sensitivity of cancer cells after chemotherapy via amphiregulin

RNA binding protein HuD contributes to β-cell dysfunction by impairing mitochondria dynamics

RNA binding protein HuD mediates the crosstalk between β cells and islet endothelial cells by the regulation of Endostatin and Serpin E1 expression

Increased hospitalizations and economic burden in COPD with bronchiectasis: a nationwide representative study

The miR-30-5p/TIA-1 axis directs cellular senescence by regulating mitochondrial dynamics

Comparison of pneumonia incidence between long-acting muscarinic antagonist and inhaled corticosteroid plus long-acting beta agonist in patients with COPD

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