Nature Search

The antibody–drug conjugate SHR-A1904 for targeting CLDN18.2 in advanced gastric or gastroesophageal junction cancer: a phase 1 trial

In this multicenter phase 1 trial, patients with advanced gastric and gastroesophageal junction cancer were safely treated with the CLDN18.2-targeting antibody–drug conjugate SHR-A1904, leading to encouraging objective response rates.

Dan-Yun Ruan
Hao-Xiang Wu
Rui-Hua Xu
Research16 Jul 2025
Nature Medicine

Volume: 31, P: 3037-3046
PPARγ phosphorylation mediated by JNK MAPK: a potential role in macrophage-derived foam cell formation

Ran Yin
Yu-gang Dong
Hong-liang Li
Research01 Sept 2006
Acta Pharmacologica Sinica

Volume: 27, P: 1146-1152
Unveiling the dynamics of little-bang nucleosynthesis

High energy nuclear collisions produce light (anti-)nuclei from the quark-gluon plasma via little-bang nucleosynthesis. Here the authors study the microscopic dynamics of little-bang nucleosynthesis producing deuterons and tritons.

Kai-Jia Sun
Rui Wang
Chun Shen
ResearchOpen Access05 Feb 2024
Nature Communications

Volume: 15, P: 1-7
The traditional Chinese medicine Qiliqiangxin in heart failure with reduced ejection fraction: a randomized, double-blind, placebo-controlled trial

In a randomized controlled trial involving patients with heart failure with reduced ejection fraction, treatment with Qiliqiangxin, a traditional Chinese medicine derived from 11 types of plants, decreased the incidence of cardiac events, as compared to placebo.

Iokfai Cheang
Wenming Yao
Xinli Li
ResearchOpen Access02 Aug 2024
Nature Medicine

Volume: 30, P: 2295-2302
Synergistic suppression of human breast cancer cells by combination of plumbagin and zoledronic acid In vitro

Han Qiao
Ting-yu Wang
Ting-ting Tang
Research03 Aug 2015
Acta Pharmacologica Sinica

Volume: 36, P: 1085-1098
Activation of AMPK inhibits cardiomyocyte hypertrophy by modulating of the FOXO1/MuRF1 signaling pathway in vitro

Bao-lin Chen
Yue-dong Ma
Yu-gang Dong
Research28 Jun 2010
Acta Pharmacologica Sinica

Volume: 31, P: 798-804
Ultrafast non-volatile flash memory based on van der Waals heterostructures

MoS₂/hBN/graphene van der Waals heterostructures with a clean interface and optimized barrier height and gate coupling ratio enable the realization of ultrafast non-volatile flash memory.

Lan Liu
Chunsen Liu
Peng Zhou
Research03 Jun 2021
Nature Nanotechnology

Volume: 16, P: 874-881
Degranulation of mast cells induced by gastric cancer-derived adrenomedullin prompts gastric cancer progression

Yi-pin Lv
Liu-sheng Peng
Yuan Zhuang
ResearchOpen Access10 Oct 2018
Cell Death & Disease

Volume: 9, P: 1-12
A phase 3 clinical trial on the immunogenicity and safety of booster vaccination after Zagreb or Essen regimens

Hua-Kun Lv
Xu Chen
Yu Mao
ResearchOpen Access27 Feb 2025
Scientific Reports

Volume: 15, P: 1-10
Co-inhibition of RAGE and TLR4 sensitizes pancreatic cancer to irreversible electroporation in mice by disrupting autophagy

Cui-fang Ye
Jia-di Wu
Jun Zhao
Research14 Feb 2025
Acta Pharmacologica Sinica

Volume: 46, P: 1757-1771
Decreased IL-17RB expression impairs CD11b⁺CD11c⁻ myeloid cell accumulation in gastric mucosa and host defense during the early-phase of Helicobacter pylori infection

Yong-sheng Teng
Yu-gang Liu
Yuan Zhuang
ResearchOpen Access28 Jan 2019
Cell Death & Disease

Volume: 10, P: 1-14
Author Correction: Synergistic suppression of human breast cancer cells by combination of plumbagin and zoledronic acid in vitro

Han Qiao
Ting-yu Wang
Ting-ting Tang
Amendments and Corrections16 May 2019
Acta Pharmacologica Sinica

Volume: 40, P: 1127-1128
Functional differences between AMPK α1 and α2 subunits in osteogenesis, osteoblast-associated induction of osteoclastogenesis, and adipogenesis

Yu-gang Wang
Xiu-guo Han
Ting-ting Tang
ResearchOpen Access07 Sept 2016
Scientific Reports

Volume: 6, P: 1-14
Biotic and Abiotic Contribution to Diurnal Soil CO₂ Fluxes from Saline/Alkaline Soils

Zhong-Yuan Wang
Jiang-Bo Xie
Yan Li
ResearchOpen Access25 Mar 2020
Scientific Reports

Volume: 10, P: 1-10
Two-dimensional materials for next-generation computing technologies

This Review discusses the recent progress and future prospects of two-dimensional materials for next-generation nanoelectronics.

Chunsen Liu
Huawei Chen
Peng Zhou
Reviews09 Jul 2020
Nature Nanotechnology

Volume: 15, P: 545-557
TATA boxes in gene transcription and poly (A) tails in mRNA stability: New perspective on the effects of berberine

Zhi-Yi Yuan
Xi Lu
Li-Jun Du
ResearchOpen Access16 Dec 2015
Scientific Reports

Volume: 5, P: 1-11
High-density lipoprotein regulates angiogenesis by long non-coding RNA HDRACA

Zhi-Wei Mo
Yue-Ming Peng
Jing-Song Ou
ResearchOpen Access14 Aug 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-18
Hsa_circ_0007456 regulates the natural killer cell-mediated cytotoxicity toward hepatocellular carcinoma via the miR-6852-3p/ICAM-1 axis

Min Shi
Zhao-Yun Li
Ya-Qiong Zhang
ResearchOpen Access18 Jan 2021
Cell Death & Disease

Volume: 12, P: 1-13
Helicobacter pylori-induced IL-33 modulates mast cell responses, benefits bacterial growth, and contributes to gastritis

Yi-pin Lv
Yong-sheng Teng
Yuan Zhuang
ResearchOpen Access25 Apr 2018
Cell Death & Disease

Volume: 9, P: 1-14
CD45⁺CD33^lowCD11b^dim myeloid-derived suppressor cells suppress CD8⁺ T cell activity via the IL-6/IL-8-arginase I axis in human gastric cancer

Fang-yuan Mao
Yong-liang Zhao
Yuan Zhuang
ResearchOpen Access09 Jul 2018
Cell Death & Disease

Volume: 9, P: 1-13
The roles of Toll-like receptor 4 in the pathogenesis of pathogen-associated biliary fibrosis caused by Clonorchis sinensis

Chao Yan
Bo Li
Kui-Yang Zheng
ResearchOpen Access20 Jun 2017
Scientific Reports

Volume: 7, P: 1-9
Kinsenoside screening with a microfluidic chip attenuates gouty arthritis through inactivating NF-κB signaling in macrophages and protecting endothelial cells

Qiao Han
Wang Bing
Tang Ting-ting
ResearchOpen Access01 Sept 2016
Cell Death & Disease

Volume: 7, P: e2350
Increased tumor-infiltrating CD45RA⁻CCR7⁻ regulatory T-cell subset with immunosuppressive properties foster gastric cancer progress

Fang-yuan Mao
Hui Kong
Yuan Zhuang
ResearchOpen Access17 Aug 2017
Cell Death & Disease

Volume: 8, P: e3002

Search

The antibody–drug conjugate SHR-A1904 for targeting CLDN18.2 in advanced gastric or gastroesophageal junction cancer: a phase 1 trial

PPARγ phosphorylation mediated by JNK MAPK: a potential role in macrophage-derived foam cell formation

Unveiling the dynamics of little-bang nucleosynthesis

The traditional Chinese medicine Qiliqiangxin in heart failure with reduced ejection fraction: a randomized, double-blind, placebo-controlled trial

Synergistic suppression of human breast cancer cells by combination of plumbagin and zoledronic acid In vitro

Activation of AMPK inhibits cardiomyocyte hypertrophy by modulating of the FOXO1/MuRF1 signaling pathway in vitro

Ultrafast non-volatile flash memory based on van der Waals heterostructures

Degranulation of mast cells induced by gastric cancer-derived adrenomedullin prompts gastric cancer progression

A phase 3 clinical trial on the immunogenicity and safety of booster vaccination after Zagreb or Essen regimens

Co-inhibition of RAGE and TLR4 sensitizes pancreatic cancer to irreversible electroporation in mice by disrupting autophagy

Decreased IL-17RB expression impairs CD11b⁺CD11c⁻ myeloid cell accumulation in gastric mucosa and host defense during the early-phase of Helicobacter pylori infection

Author Correction: Synergistic suppression of human breast cancer cells by combination of plumbagin and zoledronic acid in vitro

Functional differences between AMPK α1 and α2 subunits in osteogenesis, osteoblast-associated induction of osteoclastogenesis, and adipogenesis

Biotic and Abiotic Contribution to Diurnal Soil CO₂ Fluxes from Saline/Alkaline Soils

Two-dimensional materials for next-generation computing technologies

TATA boxes in gene transcription and poly (A) tails in mRNA stability: New perspective on the effects of berberine

High-density lipoprotein regulates angiogenesis by long non-coding RNA HDRACA

Hsa_circ_0007456 regulates the natural killer cell-mediated cytotoxicity toward hepatocellular carcinoma via the miR-6852-3p/ICAM-1 axis

Helicobacter pylori-induced IL-33 modulates mast cell responses, benefits bacterial growth, and contributes to gastritis

CD45⁺CD33^lowCD11b^dim myeloid-derived suppressor cells suppress CD8⁺ T cell activity via the IL-6/IL-8-arginase I axis in human gastric cancer

The roles of Toll-like receptor 4 in the pathogenesis of pathogen-associated biliary fibrosis caused by Clonorchis sinensis

Kinsenoside screening with a microfluidic chip attenuates gouty arthritis through inactivating NF-κB signaling in macrophages and protecting endothelial cells

Increased tumor-infiltrating CD45RA⁻CCR7⁻ regulatory T-cell subset with immunosuppressive properties foster gastric cancer progress

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