Nature Search

Data-driven subtypes of polycystic ovary syndrome and their association with clinical outcomes

This study identifies four distinct polycystic ovary syndrome (PCOS) subtypes using unsupervised clustering analysis on data from 11,908 women and validated across five diverse cohorts. The subtypes show unique clinical features and suggest that subtype-specific management could enhance treatment precision for PCOS.

Xueying Gao
Shigang Zhao
Zi-Jiang Chen
ResearchOpen Access29 Oct 2025
Nature Medicine

Volume: 31, P: 4214-4224
Author Correction: Data-driven subtypes of polycystic ovary syndrome and their association with clinical outcomes

Xueying Gao
Shigang Zhao
Zi-Jiang Chen
Amendments and CorrectionsOpen Access20 Nov 2025
Nature Medicine

Volume: 31, P: 4314
A cost-effective alkaline polysulfide-air redox flow battery enabled by a dual-membrane cell architecture

Polysulfide-air redox flow batteries are an appealing energy storage technology but suffer from polysulfide crossover and the use of costly catalysts. Here, the authors report a cell structure that enables battery operation using a cost-effective catalyst while mitigating polysulfide crossover.

Yuhua Xia
Mengzheng Ouyang
Nigel P. Brandon
ResearchOpen Access02 May 2022
Nature Communications

Volume: 13, P: 1-13
Gip1 GPCR regulates two sexual-stage differentiation processes in the ascomycete Fusarium graminearum

The development of the fruiting body (perithecium) in ascomycete fungi involves sexual differentiation processes. Here, the authors show that a non-pheromone receptor, Gip1, regulates two early stages of sexual differentiation in the wheat scab fungus Fusarium graminearum by activating cAMP signaling and Gpmk1 pathways.

Mingyu Ding
Wanshan Wang
Cong Jiang
ResearchOpen Access08 Jul 2025
Nature Communications

Volume: 16, P: 1-16
Cassava genome from a wild ancestor to cultivated varieties

Cassava is a major source of food in tropical and subtropical regions. Here the authors sequence the genomes of wild and domesticated cassava varieties and identify genes that have been selected for and against during the evolution and domestication of this economically important crop.

Wenquan Wang
Binxiao Feng
Ming Peng
ResearchOpen Access10 Oct 2014
Nature Communications

Volume: 5, P: 1-9
Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

Small cell lung cancer (SCLC) may evolve under treatment. But tumor tissues are often not available to study evolution of SCLC. Here, the authors utilize circulating tumor DNA to investigate the genomic evolution and subclonal architecture of SCLC during therapy.

Jingying Nong
Yuhua Gong
Jinghui Wang
ResearchOpen Access06 Aug 2018
Nature Communications

Volume: 9, P: 1-8
Comparison of clinical outcomes between cystotome-assisted prechop phacoemulsification surgery and femtosecond laser-assisted cataract surgery for hard nucleus cataracts

Ye He
Chao Wang
Weitao Song
Research29 Jan 2022
Eye

Volume: 37, P: 235-241
Author Correction: Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

Jingying Nong
Yuhua Gong
Jinghui Wang
Amendments and CorrectionsOpen Access29 Jan 2019
Nature Communications

Volume: 10, P: 1
The objectively measured walking speed and risk of hypertension in Chinese older adults: a prospective cohort study

Biying Zhou
Zhenger Fang
Guang Hao
Research04 Oct 2023
Hypertension Research

Volume: 47, P: 322-330
Salvage Liver Transplantation Leads to Poorer Outcome in Hepatocellular Carcinoma Compared with Primary Liver Transplantation

Yuhua Shan
Lifeng Huang
Qiang Xia
ResearchOpen Access15 Mar 2017
Scientific Reports

Volume: 7, P: 1-8
A genome-wide association study identifies six novel risk loci for primary biliary cholangitis

Primary biliary cholangitis is an autoimmune liver disease. Here, the authors show that variants in interleukin genes which potentially deregulate their expression are associated with this condition, and suggest that the IL21 signalling pathway may have a role in disease aetiology.

Fang Qiu
Ruqi Tang
Xiong Ma
ResearchOpen Access20 Apr 2017
Nature Communications

Volume: 8, P: 1-8
Vertical organic electrochemical transistors for complementary circuits

Vertical organic electrochemical transistors demonstrating unprecedented performances in both p- and n-type operation modes have been synthesized from new electro-active and ion-permeable semiconducting polymers by the interface engineering of electro-active blend layers.

Wei Huang
Jianhua Chen
Antonio Facchetti
ResearchOpen Access18 Jan 2023
Nature

Volume: 613, P: 496-502
Analysis on vaccine hesitation and its associated factors among parents of preschool children in Songgang Street, Shenzhen

Xin Shen
Xia Wu
Zuxun Lu
ResearchOpen Access08 Jun 2022
Scientific Reports

Volume: 12, P: 1-8
Deep sequencing of circulating tumor DNA detects molecular residual disease and predicts recurrence in gastric cancer

Jian Yang
Yuhua Gong
Peiwu Yu
ResearchOpen Access11 May 2020
Cell Death & Disease

Volume: 11, P: 1-9
Genomic Variants in NEURL, GJA1 and CUX2 Significantly Increase Genetic Susceptibility to Atrial Fibrillation

Pengxia Wang
Weixi Qin
Qing K. Wang
ResearchOpen Access19 Feb 2018
Scientific Reports

Volume: 8, P: 1-7
Author Correction: Ginseng glucosyl oleanolate inhibit cervical cancer cell proliferation and angiogenesis via PI3K/AKT/HIF-1α pathway

Sitong Liu
Zhiyi Ai
Yuhua Wang
Amendments and CorrectionsOpen Access25 Mar 2025
npj Science of Food

Volume: 9, P: 1
Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3

Zi-Jiang Chen and Yongyong Shi report a genome-wide association study for polycystic ovary syndrome, a common metabolic and endocrine disorder in women. They identified three susceptibility loci associated with this condition.

Zi-Jiang Chen
Han Zhao
Yueran Zhao
Research12 Dec 2010
Nature Genetics

Volume: 43, P: 55-59
ARL8B regulates lysosomal function and predicts poor prognosis in hepatocellular carcinoma

Liyan Wu
Zelin Weng
Jingping Yun
ResearchOpen Access10 Apr 2025
Scientific Reports

Volume: 15, P: 1-20
Ginseng glucosyl oleanolate inhibit cervical cancer cell proliferation and angiogenesis via PI3K/AKT/HIF-1α pathway

Sitong Liu
Zhiyi Ai
Yuhua Wang
ResearchOpen Access19 Dec 2024
npj Science of Food

Volume: 8, P: 1-13
Chromosome-level genome assembly of the tetraploid medicinal and natural dye plant Persicaria tinctoria

Qing Li
Hui Huang
Yuhua Wang
ResearchOpen Access27 Dec 2024
Scientific Data

Volume: 11, P: 1-10
Inhibition of mitochondrial complex I induces mitochondrial ferroptosis by regulating CoQH2 levels in cancer

Ru Deng
Lingyi Fu
Jingping Yun
ResearchOpen Access05 Apr 2025
Cell Death & Disease

Volume: 16, P: 1-13
Comparative analysis of mite genomes reveals positive selection for diet adaptation

Liu et al. present a comparative analysis of 15 genomes from mites and identify genetic signatures for diet specialisation. Different gene families and selective pressures were revealed for herbivorous, haematophagous and fat-feeding species.

Qiong Liu
Yuhua Deng
Lai Wei
ResearchOpen Access03 Jun 2021
Communications Biology

Volume: 4, P: 1-10
Three-dimensional printing of bioceramic-induced macrophage exosomes: immunomodulation and osteogenesis/angiogenesis

3D printing of bioceramic-induced macrophage exosomes (BC-Exos) displayed stimulatory effects on immunomodulation, osteogenesis, and angiogenesis of macrophage (MΦs), mesenchymal stem cells (MSCs) and endothelial cells (ECs), respectively. BC-Exos enhanced the expression of chemotaxis, osteogenic and angiogenic genes by altering their miRNAs profile. 3D printing of BC-Exos offers a new cell-free strategy for tissue regeneration.

Yuhua Sun
Bingjun Zhang
Chengtie Wu
ResearchOpen Access19 Nov 2021
NPG Asia Materials

Volume: 13, P: 1-16
The ATRQβ-001 vaccine improves cardiac function and prevents postinfarction cardiac remodeling in mice

Yajie Pan
Zihua Zhou
Zhihua Qiu
Research26 Dec 2018
Hypertension Research

Volume: 42, P: 329-340
De novo genome of thick-tailed pygmy jerboa Salpingotus crassicauda, Cardiocraniinae, Dipodidae

Jilong Cheng
Yu Zhang
Qisen Yang
ResearchOpen Access27 Sept 2024
Scientific Data

Volume: 11, P: 1-8
E3 ubiquitin ligase SYVN1 is a key positive regulator for GSDMD-mediated pyroptosis

Yuhua Shi
Yang Yang
Fushan Shi
ResearchOpen Access03 Feb 2022
Cell Death & Disease

Volume: 13, P: 1-14
Multi-metal 4D printing with a desktop electrochemical 3D printer

Xiaolong Chen
Xinhua Liu
Billy Wu
ResearchOpen Access08 Mar 2019
Scientific Reports

Volume: 9, P: 1-9
Genome-wide landscape of DNA methylomes and their relationship with mRNA and miRNA transcriptomes in oxidative and glycolytic skeletal muscles

Linyuan Shen
Jingjing Du
Li Zhu
ResearchOpen Access26 Aug 2016
Scientific Reports

Volume: 6, P: 1-11
Analysis of the genetic association between IL27 variants and coronary artery disease in a Chinese Han population

Qian Fan
Shaofang Nie
Xiang Cheng
ResearchOpen Access12 May 2016
Scientific Reports

Volume: 6, P: 1-8
Integrated in vitro, in silico, and in vivo approaches to elucidate the antidiabetic mechanisms of Cicer arietinum and Hordeum vulgare extract and secondary metabolites

Asif Shahzad
Wenjing Liu
Zhe Yang
ResearchOpen Access24 Feb 2025
Scientific Reports

Volume: 15, P: 1-26
Genomic and TCR profiling data reveal the distinct molecular traits in epithelial ovarian cancer histotypes

Shan Zhu
Chunliu Zhang
Yang Xiang
Research25 Apr 2022
Oncogene

Volume: 41, P: 3093-3103
Utility of cell-free DNA from bronchial washing fluid in diagnosis and genomic determination for radiology-suspected pulmonary nodules

Xinyu Zhang
Zhuo Yu
Xin Zhang
Research17 Oct 2022
British Journal of Cancer

Volume: 127, P: 2154-2165
G3BP2 regulated by the lncRNA LINC01554 facilitates esophageal squamous cell carcinoma metastasis through stabilizing HDGF transcript

Yinli Zheng
Jinjun Wu
Jingping Yun
ResearchOpen Access15 Nov 2021
Oncogene

Volume: 41, P: 515-526
The genomic architectures of tumour-adjacent tissues, plasma and saliva reveal evolutionary underpinnings of relapse in head and neck squamous cell carcinoma

Ping Wu
Chubo Xie
Yaoyun Tang
Research06 Jul 2021
British Journal of Cancer

Volume: 125, P: 854-864
Rapidly discriminate commercial medicinal Pulsatilla chinensis (Bge.) Regel from its adulterants using ITS2 barcoding and specific PCR-RFLP assay

Yuhua Shi
Mingming Zhao
Shilin Chen
ResearchOpen Access06 Jan 2017
Scientific Reports

Volume: 7, P: 1-12

Search

Data-driven subtypes of polycystic ovary syndrome and their association with clinical outcomes

Author Correction: Data-driven subtypes of polycystic ovary syndrome and their association with clinical outcomes

A cost-effective alkaline polysulfide-air redox flow battery enabled by a dual-membrane cell architecture

Gip1 GPCR regulates two sexual-stage differentiation processes in the ascomycete Fusarium graminearum

Cassava genome from a wild ancestor to cultivated varieties

Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

Comparison of clinical outcomes between cystotome-assisted prechop phacoemulsification surgery and femtosecond laser-assisted cataract surgery for hard nucleus cataracts

Author Correction: Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

The objectively measured walking speed and risk of hypertension in Chinese older adults: a prospective cohort study

Salvage Liver Transplantation Leads to Poorer Outcome in Hepatocellular Carcinoma Compared with Primary Liver Transplantation

A genome-wide association study identifies six novel risk loci for primary biliary cholangitis

Vertical organic electrochemical transistors for complementary circuits

Analysis on vaccine hesitation and its associated factors among parents of preschool children in Songgang Street, Shenzhen

Deep sequencing of circulating tumor DNA detects molecular residual disease and predicts recurrence in gastric cancer

Genomic Variants in NEURL, GJA1 and CUX2 Significantly Increase Genetic Susceptibility to Atrial Fibrillation

Author Correction: Ginseng glucosyl oleanolate inhibit cervical cancer cell proliferation and angiogenesis via PI3K/AKT/HIF-1α pathway

Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3

ARL8B regulates lysosomal function and predicts poor prognosis in hepatocellular carcinoma

Ginseng glucosyl oleanolate inhibit cervical cancer cell proliferation and angiogenesis via PI3K/AKT/HIF-1α pathway

Chromosome-level genome assembly of the tetraploid medicinal and natural dye plant Persicaria tinctoria

Inhibition of mitochondrial complex I induces mitochondrial ferroptosis by regulating CoQH2 levels in cancer

Comparative analysis of mite genomes reveals positive selection for diet adaptation

Three-dimensional printing of bioceramic-induced macrophage exosomes: immunomodulation and osteogenesis/angiogenesis

The ATRQβ-001 vaccine improves cardiac function and prevents postinfarction cardiac remodeling in mice

De novo genome of thick-tailed pygmy jerboa Salpingotus crassicauda, Cardiocraniinae, Dipodidae

E3 ubiquitin ligase SYVN1 is a key positive regulator for GSDMD-mediated pyroptosis

Multi-metal 4D printing with a desktop electrochemical 3D printer

Genome-wide landscape of DNA methylomes and their relationship with mRNA and miRNA transcriptomes in oxidative and glycolytic skeletal muscles

Analysis of the genetic association between IL27 variants and coronary artery disease in a Chinese Han population

Integrated in vitro, in silico, and in vivo approaches to elucidate the antidiabetic mechanisms of Cicer arietinum and Hordeum vulgare extract and secondary metabolites

Genomic and TCR profiling data reveal the distinct molecular traits in epithelial ovarian cancer histotypes

Utility of cell-free DNA from bronchial washing fluid in diagnosis and genomic determination for radiology-suspected pulmonary nodules

G3BP2 regulated by the lncRNA LINC01554 facilitates esophageal squamous cell carcinoma metastasis through stabilizing HDGF transcript

The genomic architectures of tumour-adjacent tissues, plasma and saliva reveal evolutionary underpinnings of relapse in head and neck squamous cell carcinoma

Rapidly discriminate commercial medicinal Pulsatilla chinensis (Bge.) Regel from its adulterants using ITS2 barcoding and specific PCR-RFLP assay

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