Neutrophils are early mediators for inflammation, but their functions in autoimmunity is still unclear. By using single cell analyses to compare patients with microscopic polyangiitis (MPA) and controls, here the authors find increased IFN-II-related neutrophils induced by IFN-γ and TNF signaling as a relapse risk marker for small vessel vasculitis.
- Masayuki Nishide
- Kei Nishimura
- Atsushi Kumanogoh
