Osteosarcoma often leads to severe complications, necessitating innovative treatments. Here, authors report a 3D-printed scaffold, HS-ICTO, integrating sono-activable and biocatalytic properties, which generates ROS for tumor eradication while promoting oxygen production to alleviate hypoxia, working towards both osteosarcoma treatment and bone repair.
- Xiao Rong
- Sutong Xiao
- Chong Cheng