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Showing 1–3 of 3 results
Advanced filters: Author: Yuki Konoeda Clear advanced filters

  • We increased the antibacterial activity and yield of styrene-based cationic particles by copolymerizing them with acrylate monomers with optimal log P values via soap-free emulsion polymerization. The cationic poly(styrene-co-methyl methacrylate) particles exhibited greater antibacterial activity than did the cationic polystyrene particles. These particles also demonstrated antiviral activity and did not mutate bacterial DNA or irritate human skin.

    • Yuki Konoeda
    • Toshikazu Tsuji
    Research
    Polymer Journal
    Volume: 57, P: 553-565

  • A total of 1074 patients with a history of ischemic stroke enrolled in The Recurrent Stroke Prevention Clinical Outcome (RESPECT) Study were assigned to intensive blood pressure (BP) control group (blood pressure < 120/80 mmHg) or standard blood pressure control group (blood pressure < 140/90 mmHg) and were followed up for a mean of 3.9 years. Seventy-eight first recurrent strokes occurred, including 70 ischemic stroke and 8 intracerebral hemorrhage. Intensive treatment did not change annual risk of ischemic stroke (1.74% vs. 1.75%, P = 0.999), but markedly reduced risk of hemorrhagic stroke (0.00% vs. 0.39%, P = 0.005). Beneficial effect of intensive BP control were observed for risk of hemorrhagic stroke in the patients with a history of ischemic stroke.

    • Kazuo Kitagawa
    • Hisatomi Arima
    • Seigo Nakada
    Research
    Hypertension Research
    Volume: 45, P: 591-601