Nature Search

Serum dopamine β-hydroxylase activity in developing hypertensive rats

TOSHIHARU NAGATSU
TAKESHI KATO
TOMIO TAKEUCHI
Research18 Oct 1974
Nature

Volume: 251, P: 630-631
Magneto-optical painting of heat current

Spin caloritronics offers advantages for the thermal management of spintronic devices. Here, the authors demonstrate that the direction of heat currents generated by spin-caloritronic phenomena can be changed by illuminating magnetic materials with visible light.

Jian Wang
Yukiko K. Takahashi
Ken-ichi Uchida
ResearchOpen Access07 Jan 2020
Nature Communications

Volume: 11, P: 1-7
Parallel labeled-line organization of sympathetic outflow for selective organ regulation in mice

How individual organs are specifically regulated by the sympathetic neurons at the cellular level remains not fully understood. Here, authors identify two molecularly distinct sympathetic pathways that independently control the adrenal medulla and intestine.

Yukiko Harima
Masafumi Tsurutani
Kazunari Miyamichi
ResearchOpen Access10 Dec 2024
Nature Communications

Volume: 15, P: 1-17
Honour, competition and cooperation across 13 societies

This online study with 3,371 participants from 13 societies found that perceived societal honour norms predicted both greater competition and greater cooperation at both societal and individual levels.

Shuxian Jin
Angelo Romano
Ayse K. Uskul
ResearchOpen Access26 Sept 2025
Nature Human Behaviour

P: 1-13
The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

Genetic mechanisms influencing COVID-19 susceptibility are not well understood. Here, the authors analyzed whole blood RNA-seq data of 465 Japanese individuals with COVID-19, highlighting thousands of fine-mapped variants affecting expression and splicing of genes, as well as the presence of COVID-19 severity-interaction eQTLs.

Qingbo S. Wang
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access22 Aug 2022
Nature Communications

Volume: 13, P: 1-19
Blood DNA virome associates with autoimmune diseases and COVID-19

Analysis of the blood DNA virome in patients with COVID-19 and autoimmune disease associates endogenous HHV-6 (eHHV-6) and high anellovirus load with increased disease risk, most notably for systemic lupus erythematosus. eHHV-6 carriers show a distinct immune response.

Noah Sasa
Shohei Kojima
Yukinori Okada
ResearchOpen Access03 Jan 2025
Nature Genetics

Volume: 57, P: 65-79
DOCK2 is involved in the host genetics and biology of severe COVID-19

A genome-wide association study highlights a variant in DOCK2, which is common in East Asian populations but rare in Europeans, as a host genetic risk factor for severe COVID-19.

Ho Namkoong
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access08 Aug 2022
Nature

Volume: 609, P: 754-760
Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution

A single-cell multiomic immune cell atlas from 235 Japanese, including patients with COVID-19 and healthy individuals, linked with host genetics including germline and somatic mutation, plasma proteomics and metagenomics data reveals that immune cells are dynamically regulated in a cell state-dependent manner.

Ryuya Edahiro
Go Sato
Yukinori Okada
ResearchOpen Access28 Jul 2025
Nature Genetics

Volume: 57, P: 1905-1921
A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

Hiroshi Suzuki
Yukiko Kurihara
Tatsuhiko Kodama
Research20 Mar 1997
Nature

Volume: 386, P: 292-296
Antecedents and consequences of telework during the COVID-19 pandemic: a natural experiment in Japan

Hiina Domae
Masataka Nakayama
Yukiko Uchida
ResearchOpen Access18 Mar 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-13
Serotonin regulates pancreatic beta cell mass during pregnancy

During pregnancy, women often become insulin resistant, thus requiring an expansion of pancreatic beta cell mass to provide more insulin. Michael German and his colleagues now report that lactogenic hormones drive the expression of serotonin in the beta cells to induce this increase in beta cell mass.

Hail Kim
Yukiko Toyofuku
Michael S German
Research27 Jun 2010
Nature Medicine

Volume: 16, P: 804-808
Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity

Peripheral blood mononuclear cells from 73 Japanese patients with coronavirus disease 2019 (COVID-19) and 75 healthy controls were analyzed using single-cell transcriptomics. Combining these data with genotyping data highlights the interplay between host genetics and the immune response in modulating disease severity.

Ryuya Edahiro
Yuya Shirai
Yukinori Okada
ResearchOpen Access24 Apr 2023
Nature Genetics

Volume: 55, P: 753-767
Magneto-optical design of anomalous Nernst thermopile

Jian Wang
Asuka Miura
Ken-ichi Uchida
ResearchOpen Access27 May 2021
Scientific Reports

Volume: 11, P: 1-8
Blood pressure during long-term cilostazol-based dual antiplatelet therapy after stroke: a post hoc analysis of the CSPS.com trial

Kazunori Toyoda
Masatoshi Koga
Hiroaki Tanaka
ResearchOpen Access09 Jul 2024
Hypertension Research

Volume: 47, P: 2238-2249
Comparison of single-unit umbilical cord blood transplantation and haploidentical transplantation using posttransplant cyclophosphamide during first complete remission of acute myeloid leukemia

Masamitsu Yanada
Satoshi Yamasaki
Takaaki Konuma
Research05 Oct 2025
Bone Marrow Transplantation

Volume: 61, P: 18-25
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
Blowflies are potential vector for avian influenza virus at enzootic area in Japan

Ryosuke Fujita
Takuji Tachi
Shinji Kasai
ResearchOpen Access04 May 2024
Scientific Reports

Volume: 14, P: 1-5
Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases

Youngjune Bhak
Vasilis Raptis
Albert Tenesa
ResearchOpen Access28 Aug 2025
Scientific Reports

Volume: 15, P: 1-16
AI feedback and workplace social support in enhancing occupational self-efficacy: a randomized controlled trial in Japan

Yasushi Watanabe
Masataka Nakayama
Yukiko Uchida
ResearchOpen Access02 Apr 2025
Scientific Reports

Volume: 15, P: 1-13
Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys

Deschloroclozapine (DCZ) is a broadly useful chemogenetic agonist for studies using nonhuman primates and mice. DCZ rapidly and reversibly activates DREADDs, and its binding can be visualized noninvasively by positron emission tomography.

Yuji Nagai
Naohisa Miyakawa
Takafumi Minamimoto
Research06 Jul 2020
Nature Neuroscience

Volume: 23, P: 1157-1167
Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls

Hiroki Masuda
Masahiro Mori
Satoshi Kuwabara
ResearchOpen Access03 Aug 2023
Scientific Reports

Volume: 13, P: 1-14
Comparative analysis of hyperfibrinolysis with activated coagulation between amniotic fluid embolism and severe placental abruption

Rui Ide
Tomoaki Oda
Naoaki Tamura
ResearchOpen Access02 Jan 2024
Scientific Reports

Volume: 14, P: 1-10
Water column gradients beneath the summer ice of a High Arctic freshwater lake as indicators of sensitivity to climate change

Paschale N. Bégin
Yukiko Tanabe
Warwick F. Vincent
ResearchOpen Access03 Feb 2021
Scientific Reports

Volume: 11, P: 1-12
Placental pathology predicts infantile neurodevelopment

Megumi Ueda
Kenji J. Tsuchiya
Hiroaki Itoh
ResearchOpen Access16 Feb 2022
Scientific Reports

Volume: 12, P: 1-10
Light quality determines primary production in nutrient-poor small lakes

Yukiko Tanabe
Makoto Hori
Masumi Yamamuro
ResearchOpen Access15 Mar 2019
Scientific Reports

Volume: 9, P: 1-8
Plasticity of histone modifications around Cidea and Cidec genes with secondary bile in the amelioration of developmentally-programmed hepatic steatosis

Jeenat Ferdous Urmi
Hiroaki Itoh
Naohiro Kanayama
ResearchOpen Access19 Nov 2019
Scientific Reports

Volume: 9, P: 1-12
Seabird-affected taluses are denitrification hotspots and potential N₂O emitters in the High Arctic

Kentaro Hayashi
Yukiko Tanabe
Masahito Hayatsu
ResearchOpen Access22 Nov 2018
Scientific Reports

Volume: 8, P: 1-11
Undernourishment in utero Primes Hepatic Steatosis in Adult Mice Offspring on an Obesogenic Diet; Involvement of Endoplasmic Reticulum Stress

Keiko Muramatsu-Kato
Hiroaki Itoh
Naohiro Kanayama
ResearchOpen Access19 Nov 2015
Scientific Reports

Volume: 5, P: 1-12
Time–outcome relationship in acute large-vessel occlusion exists across all ages: subanalysis of RESCUE-Japan Registry 2

Kenichi Todo
Shinichi Yoshimura
Naoyuki Uchiyama
ResearchOpen Access17 Jun 2021
Scientific Reports

Volume: 11, P: 1-10

Search

Serum dopamine β-hydroxylase activity in developing hypertensive rats

Magneto-optical painting of heat current

Parallel labeled-line organization of sympathetic outflow for selective organ regulation in mice

Honour, competition and cooperation across 13 societies

The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

Blood DNA virome associates with autoimmune diseases and COVID-19

DOCK2 is involved in the host genetics and biology of severe COVID-19

Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution

A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

Antecedents and consequences of telework during the COVID-19 pandemic: a natural experiment in Japan

Serotonin regulates pancreatic beta cell mass during pregnancy

Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity

Magneto-optical design of anomalous Nernst thermopile

Blood pressure during long-term cilostazol-based dual antiplatelet therapy after stroke: a post hoc analysis of the CSPS.com trial

Comparison of single-unit umbilical cord blood transplantation and haploidentical transplantation using posttransplant cyclophosphamide during first complete remission of acute myeloid leukemia

Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Blowflies are potential vector for avian influenza virus at enzootic area in Japan

Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases

AI feedback and workplace social support in enhancing occupational self-efficacy: a randomized controlled trial in Japan

Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys

Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls

Comparative analysis of hyperfibrinolysis with activated coagulation between amniotic fluid embolism and severe placental abruption

Water column gradients beneath the summer ice of a High Arctic freshwater lake as indicators of sensitivity to climate change

Placental pathology predicts infantile neurodevelopment

Light quality determines primary production in nutrient-poor small lakes

Plasticity of histone modifications around Cidea and Cidec genes with secondary bile in the amelioration of developmentally-programmed hepatic steatosis

Seabird-affected taluses are denitrification hotspots and potential N₂O emitters in the High Arctic

Undernourishment in utero Primes Hepatic Steatosis in Adult Mice Offspring on an Obesogenic Diet; Involvement of Endoplasmic Reticulum Stress

Time–outcome relationship in acute large-vessel occlusion exists across all ages: subanalysis of RESCUE-Japan Registry 2

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