Nature Search

Photo-activated ultrasound localization imaging with laser-activated nanodroplets

Shensheng Zhao and colleagues present PaUL imaging, a laser-activated nanodroplet approach that achieves super-resolution microvascular visualization. Its controllable and persistent contrast enables on-demand, multiparametric imaging for diagnostic and therapeutic use.

Shensheng Zhao
Junxi Yi
Yun-Sheng Chen
ResearchOpen Access28 Jan 2026
Communications Engineering

P: 1-12
Dynamic contrast-enhanced photoacoustic imaging using photothermal stimuli-responsive composite nanomodulators

Photoacoustic imaging becomes an enabling technology that is designed for clinic diagnosis of disease. Here, Chenet al. report an imaging contrast agent—plasmonic nanoparticles caged in hydrogel subject to reversible volume change depending on temperature, which exhibits tunable photoacoustic signal.

Yun-Sheng Chen
Soon Joon Yoon
Stanislav Emelianov
ResearchOpen Access08 Jun 2017
Nature Communications

Volume: 8, P: 1-10
Author Correction: Miniature gold nanorods for photoacoustic molecular imaging in the second near-infrared optical window

Yun-Sheng Chen
Yang Zhao
Stanislav Emelianov
Amendments and Corrections09 Jul 2019
Nature Nanotechnology

Volume: 14, P: 810
Ultra-high-frequency radio-frequency acoustic molecular imaging with saline nanodroplets in living subjects

Ultra-high-frequency radio-frequency acoustic molecular imaging is a safe molecular imaging diagnostic option because it does not require radioactive probes or high magnetic fields, but lack of biocompatible targeted contrast agents has so far limited its in vivo application. In this paper the authors present perfluorocarbon nanodroplets containing hypertonic saline solution for targeted molecular imaging of prostate cancer in animal models.

Yun-Sheng Chen
Yang Zhao
Sanjiv Sam Gambhir
Research29 Mar 2021
Nature Nanotechnology

Volume: 16, P: 717-724
Carbon-coated FeCo nanoparticles as sensitive magnetic-particle-imaging tracers with photothermal and magnetothermal properties

FeCo nanoparticles with a graphitic carbon shell decorated with poly(ethylene glycol) have photothermal and magnetothermal properties and are sensitive tracers for magnetic particle imaging, magnetic resonance imaging and photoacoustic imaging.

Guosheng Song
Michael Kenney
Jianghong Rao
Research03 Feb 2020
Nature Biomedical Engineering

Volume: 4, P: 325-334
Mitochondrial copper depletion suppresses triple-negative breast cancer in mice

Triple-negative breast cancer is inhibited by depleting mitochondrial copper in mice.

Liyang Cui
Arvin M. Gouw
Jianghong Rao
Research19 Oct 2020
Nature Biotechnology

Volume: 39, P: 357-367
Visualizing ultrafast photothermal dynamics with decoupled optical force nanoscopy

Diving deep into material insights, the authors introduce the ‘Decoupled Optical Force Nanoscopy’. This innovation uncovers the physical origins of light induced forces and captures dynamic thermal details with unparalleled nanometer precision.

Hanwei Wang
Sean M. Meyer
Yang Zhao
ResearchOpen Access10 Nov 2023
Nature Communications

Volume: 14, P: 1-9
Uncovering novel functions of NUF2 in glioblastoma and MRI-based expression prediction

Rong-de Zhong
Yun-sheng Liu
Guo-dong Huang
ResearchOpen Access01 Sept 2025
Scientific Reports

Volume: 15, P: 1-16
Miniature gold nanorods for photoacoustic molecular imaging in the second near-infrared optical window

Miniaturized gold nanorods are reliable NIR-II photoacoustic agents, showing higher photothermal stability, enhanced photoacoustic signal and more efficient agent-to-tumour delivery compared with their larger counterparts.

Yun-Sheng Chen
Yang Zhao
Stanislav Emelianov
Research04 Mar 2019
Nature Nanotechnology

Volume: 14, P: 465-472
Hybrid photoacoustic and fast super-resolution ultrasound imaging

Dual photoacoustic and fast super-resolution ultrasound imaging technique bridges the physiological and structural details in vivo. The authors demonstrated that this interleaved technology allows revealing the transient changes of blood flow and blood oxygenation over time.

Shensheng Zhao
Jonathan Hartanto
Yun-Sheng Chen
ResearchOpen Access18 Apr 2023
Nature Communications

Volume: 14, P: 1-14
Structural insight into the mechanism of synergistic autoinhibition of SAD kinases

The SAD kinases contain a UBA domain that binds to the kinase domain and has a role in autoinhibition and allosteric activation of the AMPK homoenzyme. Here, the authors identify an autoinhibitory sequence in SAD and show that the UBA domain synergistically functions as an autoinhibitory domain.

Jing-Xiang Wu
Yun-Sheng Cheng
Jia-Wei Wu
ResearchOpen Access02 Dec 2015
Nature Communications

Volume: 6, P: 1-12
Initial meconium microbiome in Chinese neonates delivered naturally or by cesarean section

Yi-Chao Shi
He Guo
Yun-Sheng Yang
ResearchOpen Access19 Feb 2018
Scientific Reports

Volume: 8, P: 1-12
FAM122A is required for hematopoietic stem cell function

Man-Hua Liu
Xiao-Cui Zhang
Ying Huang
Research01 Dec 2020
Leukemia

Volume: 35, P: 2130-2134
T cell-redirecting antibody for treatment of solid tumors via targeting mesothelin

Jun-jun Liu
Zhi-di Pan
Jian-wei Zhu
Research10 Jun 2024
Acta Pharmacologica Sinica

Volume: 45, P: 2186-2198
Fibroblasts play a potential role in bone destruction via osteopontin related caldesmon expression and polymerization in human non-functioning pituitary adenomas

Li-yang Zhang
Xiao-lu Ge
Zhi-Xiong Liu
ResearchOpen Access13 Dec 2017
Scientific Reports

Volume: 7, P: 1-10
Photoacoustics of core–shell nanospheres using comprehensive modeling and analytical solution approach

Photoacoustic imaging of colloidal nanosystems is a useful tool for biological applications, yet current models of the photo-induced thermal processes contain un-physical assumptions. Here, the authors propose a model capable of disentangling the role of the nanoparticle, shell, surrounding material, and laser pulse properties.

Khosro Shahbazi
Wolfgang Frey
Stanislav Emelianov
ResearchOpen Access30 Sept 2019
Communications Physics

Volume: 2, P: 1-11
Metagenomic analysis of the pinewood nematode microbiome reveals a symbiotic relationship critical for xenobiotics degradation

Xin-Yue Cheng
Xue-Liang Tian
Bing-Yan Xie
ResearchOpen Access22 May 2013
Scientific Reports

Volume: 3, P: 1-10
Perspectives of chiral nanophotonics: from mechanisms to biomedical applications

Seongmin Im
Seyedehniousha Mousavi
Yang Zhao
ReviewsOpen Access04 Dec 2024
npj Nanophotonics

Volume: 1, P: 1-20

Search

Photo-activated ultrasound localization imaging with laser-activated nanodroplets

Dynamic contrast-enhanced photoacoustic imaging using photothermal stimuli-responsive composite nanomodulators

Author Correction: Miniature gold nanorods for photoacoustic molecular imaging in the second near-infrared optical window

Ultra-high-frequency radio-frequency acoustic molecular imaging with saline nanodroplets in living subjects

Carbon-coated FeCo nanoparticles as sensitive magnetic-particle-imaging tracers with photothermal and magnetothermal properties

Mitochondrial copper depletion suppresses triple-negative breast cancer in mice

Visualizing ultrafast photothermal dynamics with decoupled optical force nanoscopy

Uncovering novel functions of NUF2 in glioblastoma and MRI-based expression prediction

Miniature gold nanorods for photoacoustic molecular imaging in the second near-infrared optical window

Hybrid photoacoustic and fast super-resolution ultrasound imaging

Structural insight into the mechanism of synergistic autoinhibition of SAD kinases

Initial meconium microbiome in Chinese neonates delivered naturally or by cesarean section

FAM122A is required for hematopoietic stem cell function

T cell-redirecting antibody for treatment of solid tumors via targeting mesothelin

Fibroblasts play a potential role in bone destruction via osteopontin related caldesmon expression and polymerization in human non-functioning pituitary adenomas

Photoacoustics of core–shell nanospheres using comprehensive modeling and analytical solution approach

Metagenomic analysis of the pinewood nematode microbiome reveals a symbiotic relationship critical for xenobiotics degradation

Perspectives of chiral nanophotonics: from mechanisms to biomedical applications

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