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Showing 1–50 of 69 results

Advanced filters: Author: Yusuke Kawamura Clear advanced filters

Publisher Correction: A genome-wide association analysis reveals new pathogenic pathways in gout

Tanya J. Major
Riku Takei
Tony R. Merriman
Amendments and Corrections05 Nov 2024
Nature Genetics

Volume: 56, P: 2577
Comparison of Oxford versus Japanese Histological Grading to predict renal function decline in IgA nephropathy: a Japanese prospective cohort study

Ryoko Sakaguchi
Kensuke Joh
Yusuke Suzuki
ResearchOpen Access02 Feb 2026
Scientific Reports

P: 1-10
DOCK2 is involved in the host genetics and biology of severe COVID-19

A genome-wide association study highlights a variant in DOCK2, which is common in East Asian populations but rare in Europeans, as a host genetic risk factor for severe COVID-19.

Ho Namkoong
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access08 Aug 2022
Nature

Volume: 609, P: 754-760
Staphylococcus aureus ST764-SCCmecII high-risk clone in bloodstream infections revealed through national genomic surveillance integrating clinical data

Authors present results from a national surveillance in Japan that found MRSA strains causing bloodstream infections are predominantly from three clonal lineages. They also identified the emergence of highest 30-day-mortality MRSA clone ST764-SCCmecII and traced its evolutionary path.

Junzo Hisatsune
Shoko Kutsuno
Motoyuki Sugai
ResearchOpen Access19 Mar 2025
Nature Communications

Volume: 16, P: 1-14
Blood DNA virome associates with autoimmune diseases and COVID-19

Analysis of the blood DNA virome in patients with COVID-19 and autoimmune disease associates endogenous HHV-6 (eHHV-6) and high anellovirus load with increased disease risk, most notably for systemic lupus erythematosus. eHHV-6 carriers show a distinct immune response.

Noah Sasa
Shohei Kojima
Yukinori Okada
ResearchOpen Access03 Jan 2025
Nature Genetics

Volume: 57, P: 65-79
The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

Genetic mechanisms influencing COVID-19 susceptibility are not well understood. Here, the authors analyzed whole blood RNA-seq data of 465 Japanese individuals with COVID-19, highlighting thousands of fine-mapped variants affecting expression and splicing of genes, as well as the presence of COVID-19 severity-interaction eQTLs.

Qingbo S. Wang
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access22 Aug 2022
Nature Communications

Volume: 13, P: 1-19
Soluble Polyimides Based on 2,3,5-Tricarboxycyclopentyl Acetic Dianhydride

Yusuke Tsuda
Yukio Tanaka
Nobuo Bessho
Research01 Jul 1997
Polymer Journal

Volume: 29, P: 574-579
Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution

A single-cell multiomic immune cell atlas from 235 Japanese, including patients with COVID-19 and healthy individuals, linked with host genetics including germline and somatic mutation, plasma proteomics and metagenomics data reveals that immune cells are dynamically regulated in a cell state-dependent manner.

Ryuya Edahiro
Go Sato
Yukinori Okada
ResearchOpen Access28 Jul 2025
Nature Genetics

Volume: 57, P: 1905-1921
Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity

Peripheral blood mononuclear cells from 73 Japanese patients with coronavirus disease 2019 (COVID-19) and 75 healthy controls were analyzed using single-cell transcriptomics. Combining these data with genotyping data highlights the interplay between host genetics and the immune response in modulating disease severity.

Ryuya Edahiro
Yuya Shirai
Yukinori Okada
ResearchOpen Access24 Apr 2023
Nature Genetics

Volume: 55, P: 753-767
Quantized surface transport in topological Dirac semimetal films

The recent observation of quantum Hall states in bulk Dirac semimetal Cd₃As₂ is possibly evolved from topological states. Here, Nishihaya et al. report surface quantum oscillation and its evolution into quantum Hall states in Cd₃As₂ thin films, where unconventional bulk states involve in quantized surface transport.

Shinichi Nishihaya
Masaki Uchida
Masashi Kawasaki
ResearchOpen Access12 Jun 2019
Nature Communications

Volume: 10, P: 1-7
Author Correction: Immune evasion through mitochondrial transfer in the tumour microenvironment

Hideki Ikeda
Katsushige Kawase
Yosuke Togashi
Amendments and CorrectionsOpen Access25 Jul 2025
Nature

Volume: 644, P: E33
Immune evasion through mitochondrial transfer in the tumour microenvironment

Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired antitumour immunity.

Hideki Ikeda
Katsushige Kawase
Yosuke Togashi
ResearchOpen Access22 Jan 2025
Nature

Volume: 638, P: 225-236
Local-structure insight into the improved superconducting properties of Pb-substituted La(O, F)BiS₂: a photoelectron holography study

YaJun Li
Yusuke Hashimoto
Takayoshi Yokoya
ResearchOpen Access11 Mar 2025
Scientific Reports

Volume: 15, P: 1-7
A genome-wide association analysis reveals new pathogenic pathways in gout

Genome-wide association analysis of gout and urate identifies 148 new loci, implicating biological pathways and prioritizing candidate genes involved in inflammatory processes.

Tanya J. Major
Riku Takei
Tony R. Merriman
Research15 Oct 2024
Nature Genetics

Volume: 56, P: 2392-2406
Visualization of AMPA receptors in living human brain with positron emission tomography

A newly developed PET tracer allows visualization of AMPA receptors in the living human brain, providing a new tool to study their potential involvement in neurological or psychiatric disorders.

Tomoyuki Miyazaki
Waki Nakajima
Takuya Takahashi
Research20 Jan 2020
Nature Medicine

Volume: 26, P: 281-288
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Micro Fabry-Pérot Interferometer at Rayleigh Range

Yusuke Tsujiie
Yoshiyuki Kawamura
ResearchOpen Access12 Oct 2018
Scientific Reports

Volume: 8, P: 1-6
Publisher Correction: Immune evasion through mitochondrial transfer in the tumour microenvironment

Hideki Ikeda
Katsushige Kawase
Yosuke Togashi
Amendments and CorrectionsOpen Access13 Feb 2025
Nature

Volume: 639, P: E5
Quantum Hall states observed in thin films of Dirac semimetal Cd₃As₂

Despite many achievements in the topological semimetal Cd₃As₂, the high-quality Cd₃As₂ films are still rare. Here, Uchida et al. grow high-crystallinity and high-mobility Cd₃As₂ thin films and observe quantum Hall states dependent on the confinement thickness.

Masaki Uchida
Yusuke Nakazawa
Masashi Kawasaki
ResearchOpen Access22 Dec 2017
Nature Communications

Volume: 8, P: 1-7
Soluble Polyimides and Copolyimides Based on Alicyclic Dianhydride Having Cyclohexene and Tetralin Moieties

Yusuke Tsuda
Renpei Kuwahara
Jae Min Oh
Research05 Feb 2005
Polymer Journal

Volume: 37, P: 126-132
Soluble Copolyimides Based on 2,3,5-Tricarboxycyclopentyl Acetic Dianhydride and Conventional Aromatic Tetracarboxylic Dianhydrides

Yusuke Tsuda
Kenichi Etou
Nobuo Bessho
Research01 Mar 1998
Polymer Journal

Volume: 30, P: 222-228
A fungal sesquiterpene biosynthesis gene cluster critical for mutualist-pathogen transition in Colletotrichum tofieldiae

Plant-associated fungi range from pathogens to mutualists. Here the authors identify a gene cluster in a Colletotrichum tofieldiae strain that is required to allow the fungus to transition from a mutualist to a pathogen depending on the nutritional status of the host.

Kei Hiruma
Seishiro Aoki
Yusuke Saijo
ResearchOpen Access06 Sept 2023
Nature Communications

Volume: 14, P: 1-18
Lactate biosensors for spectrally and spatially multiplexed fluorescence imaging

l-Lactate is increasingly recognized as a key metabolite and signalling molecule in mammals, but the methods to investigate it in vivo have been limited. Here, authors report a pair of improved biosensors—one green and one red—for visualizing l-lactate both inside and outside of cells.

Yusuke Nasu
Abhi Aggarwal
Robert E. Campbell
ResearchOpen Access27 Oct 2023
Nature Communications

Volume: 14, P: 1-17
Decreased extra-renal urate excretion is a common cause of hyperuricemia

Hyperuricemia, or gout, is thought to arise either from urate overproduction or from decreased renal excretion of urate. Ichidaet al. show that the extra-renal excretion of urate also has a role in the pathogenesis of hyperuricemia, and propose a new classification for patients with this disease.

Kimiyoshi Ichida
Hirotaka Matsuo
Hiroshi Suzuki
ResearchOpen Access03 Apr 2012
Nature Communications

Volume: 3, P: 1-7
Use of near-infrared imaging using indocyanine green associates with the lower incidence of postoperative complications for intestinal and mesenteric injury

Keishi Yamaguchi
Takeru Abe
Ichiro Takeuchi
ResearchOpen Access13 Dec 2021
Scientific Reports

Volume: 11, P: 1-7
Characterization of an active LINE-1 in the naked mole-rat genome

Shunichi Yamaguchi
Shizuka Nohara
Tomoyuki Honda
ResearchOpen Access11 Mar 2021
Scientific Reports

Volume: 11, P: 1-8
Soluble Polyimides Based on Long-chain Alkyl Groups via Amide Linkages

Yusuke Tsuda
Manami Kojima
Jae Min Oh
Research04 Mar 2008
Polymer Journal

Volume: 40, P: 354-366
Effectiveness of negative pressure wound therapy with instillation and dwelling after stoma closure: a retrospective and propensity score matching analysis

Yoshinori Yane
Jin-ichi Hida
Junichiro Kawamura
ResearchOpen Access18 Jan 2022
Scientific Reports

Volume: 12, P: 1-8
Super-wide viewing-zone holographic 3D display using a convex parabolic mirror

Yusuke Sando
Kazuo Satoh
Toyohiko Yatagai
ResearchOpen Access27 Jul 2018
Scientific Reports

Volume: 8, P: 1-8
Synthesis of Soluble Polyimides Based on Alicyclic Dianhydride in Ionic Liquids

Yusuke Tsuda
Tetsuya Yoshida
Takahiko Kakoi
Reviews15 Oct 2006
Polymer Journal

Volume: 38, P: 88-90
Development and validation of predictive model for emesis in cervical cancer patients receiving concurrent chemoradiotherapy based on multi-institutional retrospective study

Kensuke Yoshida
Hajime Morita
Munetoshi Sugiura
ResearchOpen Access27 Oct 2025
Scientific Reports

Volume: 15, P: 1-9
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload

Hirotaka Matsuo
Akiyoshi Nakayama
Nariyoshi Shinomiya
ResearchOpen Access20 Jan 2014
Scientific Reports

Volume: 4, P: 1-5
Common dysfunctional variants in ABCG2 are a major cause of early-onset gout

Hirotaka Matsuo
Kimiyoshi Ichida
Nariyoshi Shinomiya
ResearchOpen Access18 Jun 2013
Scientific Reports

Volume: 3, P: 1-4
Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors

Akiyoshi Nakayama
Hirotaka Matsuo
Nariyoshi Shinomiya
ResearchOpen Access09 Jun 2014
Scientific Reports

Volume: 4, P: 1-5
Identification and replication of sex-dimorphic protein quantitative trait loci across multiple ancestries and their associations with diseases

Youngjune Bhak
Vasilis Raptis
Albert Tenesa
ResearchOpen Access28 Aug 2025
Scientific Reports

Volume: 15, P: 1-16
Eomes transcription factor is required for the development and differentiation of invariant NKT cells

Kanako Shimizu, Yusuke Sato et al. examine the impact of the Eomes transcription factor on invariant NKT (iNKT) cell differentiation using conditional knockout mice. They show that Eomes is needed for the development of iNKT1 cells in the thymus, and for their activation and differentiation in peripheral tissues.

Kanako Shimizu
Yusuke Sato
Shin-ichiro Fujii
ResearchOpen Access29 Apr 2019
Communications Biology

Volume: 2, P: 1-13
Soluble Polyimides Based on Alkyloxydiaminobenzene

Yusuke Tsuda
Kenichi Kanegae
Satoshi Yasukouchi
Research01 Nov 2000
Polymer Journal

Volume: 32, P: 941-947
Proteinuria as a Significant Determinant of Hypertension in a Normotensive Screened Cohort in Okinawa, Japan

Taku Inoue
Kunitoshi Iseki
Shuichi Takishita
Research01 Sept 2006
Hypertension Research

Volume: 29, P: 687-693
Soluble Polyimides Based on Alkyldiaminobenzophenone

Yusuke Tsuda
Takehiro Kawauchi
Shuntaro Mataka
Research01 Jul 2000
Polymer Journal

Volume: 32, P: 594-601
Plates made from magnesium alloy with a long period stacking ordered structure promote bone formation in a rabbit fracture model

Kosei Takata
Masaki Yugami
Takeshi Miyamoto
ResearchOpen Access10 Apr 2025
Scientific Reports

Volume: 15, P: 1-9
Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals

Masahiro Nakatochi et al. report a genome-wide meta-analysis of serum uric acid levels in the Japanese population. They identify 36 loci, including eight previously unreported loci, suggesting key cellular processes that contribute to elevated serum uric acid levels, which can lead to gout.

Masahiro Nakatochi
Masahiro Kanai
Hirotaka Matsuo
ResearchOpen Access08 Apr 2019
Communications Biology

Volume: 2, P: 1-10
Silane- and peroxide-free hydrogen atom transfer hydrogenation using ascorbic acid and cobalt-photoredox dual catalysis

Hydrogen atom transfer (HAT) hydrogenation of alkenes usually requires stoichiometric silanes and peroxides. Here, the authors report a silane- and peroxide-free HAT hydrogenation method using a combined cobalt/photoredox catalysis and vitamin C as a sole stoichiometric reactant.

Yuji Kamei
Yusuke Seino
Shigeki Matsunaga
ResearchOpen Access11 Feb 2021
Nature Communications

Volume: 12, P: 1-9
UBL3 modification influences protein sorting to small extracellular vesicles

Exosomes mediate cell-to-cell communication by transporting proteins, mRNAs, and miRNAs but the mechanisms of protein sorting to exosomes are poorly understood. Here, the authors uncover that ubiquitin-like 3 (UBL3) regulates protein sorting to exosomes by acting as a posttranslational modification.

Hiroshi Ageta
Natsumi Ageta-Ishihara
Kunihiro Tsuchida
ResearchOpen Access26 Sept 2018
Nature Communications

Volume: 9, P: 1-12
Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population

Yuta Kochi and colleagues report a meta-analysis of genome-wide association studies for rheumatoid arthritis in a Japanese population. They identify nine loci newly associated with rheumatoid arthritis in this population and consider overlap of associations with previous studies in European populations.

Yukinori Okada
Chikashi Terao
Kazuhiko Yamamoto
Research25 Mar 2012
Nature Genetics

Volume: 44, P: 511-516
Carbonaceous aerosol tracers in ice-cores record multi-decadal climate oscillations

Osamu Seki
Kimitaka Kawamura
Yoshiyuki Fujii
ResearchOpen Access28 Sept 2015
Scientific Reports

Volume: 5, P: 1-10
Possible mechanism for improving the endogenous immune system through the blockade of peripheral μ-opioid receptors by treatment with naldemedine

Eizoh Gondoh
Yusuke Hamada
Minoru Narita
Research09 Aug 2022
British Journal of Cancer

Volume: 127, P: 1565-1574
Soluble Polyimides Based on Diaminobenzoic Acid Alkylester

Yusuke Tsuda
Manami Kojima
Jae Min Oh
Reviews30 Aug 2006
Polymer Journal

Volume: 38, P: 1043-1054
Effect of febuxostat on left ventricular diastolic function in patients with asymptomatic hyperuricemia: a sub analysis of the PRIZE Study

Kenya Kusunose
Hisako Yoshida
Mikiko Kagiyama
ResearchOpen Access17 Oct 2021
Hypertension Research

Volume: 45, P: 106-115
Factors associated with carotid intima-media thickness progression in patients with asymptomatic hyperuricemia: insights from the PRIZE study

Yuichi Saito
Atsushi Tanaka
Mikiko Kagiyama
ResearchOpen Access05 Jul 2023
Scientific Reports

Volume: 13, P: 1-10

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