Nature Search

Staphylococcus aureus ST764-SCCmecII high-risk clone in bloodstream infections revealed through national genomic surveillance integrating clinical data

Authors present results from a national surveillance in Japan that found MRSA strains causing bloodstream infections are predominantly from three clonal lineages. They also identified the emergence of highest 30-day-mortality MRSA clone ST764-SCCmecII and traced its evolutionary path.

Junzo Hisatsune
Shoko Kutsuno
Motoyuki Sugai
ResearchOpen Access19 Mar 2025
Nature Communications

Volume: 16, P: 1-14
Pan-cancer prevalence, risk, and clinical and demographic characteristics of Lynch Syndrome-associated variants in BioBank Japan

Mizukami et al. analyze DNA from over 110,000 individuals, covering 23 cancer types and controls, to characterize carriers of pathogenic variants in Lynch syndrome genes. Their results clarify carrier frequencies, cancer risks, and clinical features including diagnosed age, multiple cancers, and family history.

Keijiro Mizukami
Yoshiaki Usui
Yukihide Momozawa
ResearchOpen Access13 Nov 2025
Communications Medicine

Volume: 5, P: 1-12
Induction of interleukin-8 preserves the angiogenic response in HIF-1α–deficient colon cancer cells

Yusuke Mizukami
Won-Seok Jo
Daniel C Chung
Research28 Aug 2005
Nature Medicine

Volume: 11, P: 992-997
A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer

Advanced colorectal cancers are characterised by intra-tumour heterogeneity dictated by neutral evolution. Here the authors analyse early colorectal tumours by whole-exome sequencing and find that Darwinian evolution determines the fate of early lesions in colorectal adenoma and carcinoma in situ.

Tomoko Saito
Atsushi Niida
Koshi Mimori
ResearchOpen Access23 Jul 2018
Nature Communications

Volume: 9, P: 1-11
Pioglitazone, a Thiazolidinedione Derivative, Attenuates Left Ventricular Hypertrophy and Fibrosis in Salt-Sensitive Hypertension

Minori Nakamoto
Yusuke Ohya
Shuichi Takishita
Research01 Feb 2008
Hypertension Research

Volume: 31, P: 353-361
High dynamic range capillary electrophoresis method for sensitive detection of low-frequency driver mutations

Nobue Tamamura
Yoshihiko Hagiwara
Yusuke Mizukami
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-11
Double dome structure of the Bose–Einstein condensation in diluted S = 3/2 quantum magnets

Previous studies of magnetic Bose–Einstein condensates have been limited to magnetic materials with small spin numbers. Here the authors study the magnetic phase diagram of a S = 3/2 quantum antiferromagnet and show a double dome structure that is attributed to different types of condensates.

Yoshito Watanabe
Atsushi Miyake
Taka-hisa Arima
ResearchOpen Access10 Mar 2023
Nature Communications

Volume: 14, P: 1-9
Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism

Bardeesy and colleagues show that mutant GNAS suppresses salt-inducible kinases by activating PKA, leading to lipid remodelling and pancreatic tumourigenesis

Krushna C. Patra
Yasutaka Kato
Nabeel Bardeesy
Research25 Jun 2018
Nature Cell Biology

Volume: 20, P: 811-822
Genomic insights into familial adenomatous polyposis: unraveling a rare case with whole APC gene deletion and intellectual disability

Hiroki Tanabe
Masami Ijiri
Toshikatsu Okumura
ResearchOpen Access29 Mar 2024
Human Genome Variation

Volume: 11, P: 1-4
Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derived mutations from fine-needle aspirates using digital PCR

Yusuke Ono
Akihiro Hayashi
Toshikatsu Okumura
ResearchOpen Access23 Jul 2020
Scientific Reports

Volume: 10, P: 1-10
High-resolution genetic analysis of whole APC gene deletions: a report of two cases and patient characteristics

Hiroki Tanabe
Yasuyuki Koshizuka
Yoshio Makita
ResearchOpen Access04 Dec 2024
Human Genome Variation

Volume: 11, P: 1-5
Metachronous intraductal papillary mucinous neoplasms disseminate via the pancreatic duct following resection

Kazumasa Nagai
Yusuke Mizukami
Akio Katanuma
Research13 Nov 2019
Modern Pathology

Volume: 33, P: 971-980
Giant tunability of magnetoelasticity in Fe₄N system as a platform to unveil correlation between magnetostriction and magnetic damping

Magnetoelasticity-based miniaturized strain sensors are promising for developing flexible spintronics and wearable electronics applications. Here, a wide range tunability of magnetoelastic properties is demonstrated in magnetic nitrides by partially replacing Fe with Co or Mn.

Keita Ito
Ivan Kurniawan
Takeshi Seki
ResearchOpen Access26 Mar 2025
Communications Materials

Volume: 6, P: 1-8
Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses

Daisuke Oikawa et al. provide structural insights into how small-molecule inhibitors of LUBAC ubiquitin ligase, HOIPINs, bind to LUBAC. They find that HOIPINs trigger apoptosis in lymphoma cells and alleviate psoriasis in mice, suggesting the potential therapeutic utility of HOIPINs.

Daisuke Oikawa
Yusuke Sato
Fuminori Tokunaga
ResearchOpen Access03 Apr 2020
Communications Biology

Volume: 3, P: 1-17
Amygdala-centred functional connectivity affects daily cortisol concentrations: a putative link with anxiety

Yuko Hakamata
Shotaro Komi
Hirokuni Tagaya
ResearchOpen Access16 Aug 2017
Scientific Reports

Volume: 7, P: 1-11
Impact of radiation doses on clinical relapse of biochemically recurrent prostate cancer after prostatectomy

Seiya Takano
Natsuo Tomita
Akio Hiwatashi
ResearchOpen Access02 Jan 2024
Scientific Reports

Volume: 14, P: 1-10

Search

Staphylococcus aureus ST764-SCCmecII high-risk clone in bloodstream infections revealed through national genomic surveillance integrating clinical data

Pan-cancer prevalence, risk, and clinical and demographic characteristics of Lynch Syndrome-associated variants in BioBank Japan

Induction of interleukin-8 preserves the angiogenic response in HIF-1α–deficient colon cancer cells

A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer

Pioglitazone, a Thiazolidinedione Derivative, Attenuates Left Ventricular Hypertrophy and Fibrosis in Salt-Sensitive Hypertension

High dynamic range capillary electrophoresis method for sensitive detection of low-frequency driver mutations

Double dome structure of the Bose–Einstein condensation in diluted S = 3/2 quantum magnets

Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism

Genomic insights into familial adenomatous polyposis: unraveling a rare case with whole APC gene deletion and intellectual disability

Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derived mutations from fine-needle aspirates using digital PCR

High-resolution genetic analysis of whole APC gene deletions: a report of two cases and patient characteristics

Metachronous intraductal papillary mucinous neoplasms disseminate via the pancreatic duct following resection

Giant tunability of magnetoelasticity in Fe₄N system as a platform to unveil correlation between magnetostriction and magnetic damping

Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses

Amygdala-centred functional connectivity affects daily cortisol concentrations: a putative link with anxiety

Impact of radiation doses on clinical relapse of biochemically recurrent prostate cancer after prostatectomy

Search

Quick links

Search

Filter By:

Search

Quick links