Nature Search

Heat shock protein gp96 drives natural killer cell maturation and anti-tumor immunity by counteracting Trim28 to stabilize Eomes

Natural killer (NK) cell maturation and function are regulated by multiple transcription factors (TF), but detailed molecular insights are scarce. Here the authors show that a TF, Eomes, is important for NK cell responses and cancer surveillance, in which Eomes expression is regulated by gp96 and Trim28 via the ubiquitination and degradation pathways.

Yuxiu Xu
Xin Li
Songdong Meng
ResearchOpen Access06 Feb 2024
Nature Communications

Volume: 15, P: 1-15
Nuclear SREBP2 condensates regulate the transcriptional activation of lipogenic genes and cholesterol homeostasis

Nuclear SREBP2 forms nuclear condensates through its N-terminal intrinsically disordered region, which is essential for the transcriptional activation of lipogenic genes.

Mengqiang Xu
Shi-You Jiang
Wei Qi
Research20 May 2025
Nature Metabolism

Volume: 7, P: 1034-1051
Correction: Corrigendum: In situ targeted MRI detection of Helicobacter pylori with stable magnetic graphitic nanocapsules

Yunjie Li
Xiaoxiao Hu
Weihong Tan
Amendments and CorrectionsOpen Access30 Aug 2017
Nature Communications

Volume: 8, P: 1-2
Field validation of the performance of paper-based tests for the detection of the Zika and chikungunya viruses in serum samples

Double-blinded studies show that paper-based diagnostic tests and a companion portable device designed for use in low-resource settings perform well for the diagnosis of the Zika and chikungunya viruses in serum samples.

Margot Karlikow
Severino Jefferson Ribeiro da Silva
Keith Pardee
ResearchOpen Access07 Mar 2022
Nature Biomedical Engineering

Volume: 6, P: 246-256
Sex-specific associations of intrapancreatic fat deposition with incident type 2 diabetes

Wang et al. examine the sex-specific associations of intrapancreatic fat deposition (IPFD) with incident type 2 diabetes (T2D) using the UK biobank cohort. IPFD is associated with incident T2D independent of BMI, hepatic fat and visceral fat in men and independent of BMI and hepatic fat in women.

Xuechen Wang
Yucheng Yang
Yuxiu Li
ResearchOpen Access28 Nov 2025
Communications Medicine

Volume: 5, P: 1-7
Protective factors contributing to the health status of construction industry migrant workers in Chinese mainland

Yuxiu Bai
Yingying Lin
Rufang Ye
ResearchOpen Access30 Jan 2025
Scientific Reports

Volume: 15, P: 1-10
In situ targeted MRI detection of Helicobacter pylori with stable magnetic graphitic nanocapsules

The effective detection ofHelicobacter pylori has been a challenge clinically. Here, the authors demonstrate the potential of magnetic nanoparticles for non-invasive diagnosis of H. pylori using magnetic resonance imaging in vivo.

Yunjie Li
Xiaoxiao Hu
Weihong Tan
ResearchOpen Access15 Jun 2017
Nature Communications

Volume: 8, P: 1-12
Numerical simulation of water and salt transport during the re-injection process of farmland drainage

Siyu Chen
Ke Yang
Ge Zhang
ResearchOpen Access26 Sept 2025
Scientific Reports

Volume: 15, P: 1-12
An eighteen-organ microphysiological system coupling a vascular network and excretion system for drug discovery

Jing Wang
Huixue Zhang
Yong Luo
ResearchOpen Access14 May 2025
Microsystems & Nanoengineering

Volume: 11, P: 1-14
Combined serum levels of multiple proteins in tPA-BDNF pathway may aid the diagnosis of five mental disorders

Suzhen Chen
Haitang Jiang
Yonggui Yuan
ResearchOpen Access31 Jul 2017
Scientific Reports

Volume: 7, P: 1-9
Role of peripheral cytokines and orbitofrontal cortex subregion structure in schizophrenia agitation

Yingbo Dong
Yilin Tang
Yuxiu Sui
ResearchOpen Access23 Apr 2025
Scientific Reports

Volume: 15, P: 1-15
Microanchored borehole fiber optics allows strain profiling of the shallow subsurface

Cheng-Cheng Zhang
Bin Shi
Guang-Qing Wei
ResearchOpen Access28 Apr 2021
Scientific Reports

Volume: 11, P: 1-12
Structural and Functional Connectivity of Default Mode Network underlying the Cognitive Impairment in Late-onset Depression

Yingying Yin
Xiaofu He
Yonggui Yuan
ResearchOpen Access25 Nov 2016
Scientific Reports

Volume: 6, P: 1-10
TiO₂ nanoparticles functionalized by Pd nanoparticles for gas-sensing application with enhanced butane response performances

Nan Chen
Dongyang Deng
Yude Wang
ResearchOpen Access09 Aug 2017
Scientific Reports

Volume: 7, P: 1-11
A general nonaqueous sol-gel route to g-C₃N₄-coupling photocatalysts: the case of Z-scheme g-C₃N₄/TiO₂ with enhanced photodegradation toward RhB under visible-light

Xu Liu
Nan Chen
Yude Wang
ResearchOpen Access22 Dec 2016
Scientific Reports

Volume: 6, P: 1-16

Search

Heat shock protein gp96 drives natural killer cell maturation and anti-tumor immunity by counteracting Trim28 to stabilize Eomes

Nuclear SREBP2 condensates regulate the transcriptional activation of lipogenic genes and cholesterol homeostasis

Correction: Corrigendum: In situ targeted MRI detection of Helicobacter pylori with stable magnetic graphitic nanocapsules

Field validation of the performance of paper-based tests for the detection of the Zika and chikungunya viruses in serum samples

Sex-specific associations of intrapancreatic fat deposition with incident type 2 diabetes

Protective factors contributing to the health status of construction industry migrant workers in Chinese mainland

In situ targeted MRI detection of Helicobacter pylori with stable magnetic graphitic nanocapsules

Numerical simulation of water and salt transport during the re-injection process of farmland drainage

An eighteen-organ microphysiological system coupling a vascular network and excretion system for drug discovery

Combined serum levels of multiple proteins in tPA-BDNF pathway may aid the diagnosis of five mental disorders

Role of peripheral cytokines and orbitofrontal cortex subregion structure in schizophrenia agitation

Microanchored borehole fiber optics allows strain profiling of the shallow subsurface

Structural and Functional Connectivity of Default Mode Network underlying the Cognitive Impairment in Late-onset Depression

TiO₂ nanoparticles functionalized by Pd nanoparticles for gas-sensing application with enhanced butane response performances

A general nonaqueous sol-gel route to g-C₃N₄-coupling photocatalysts: the case of Z-scheme g-C₃N₄/TiO₂ with enhanced photodegradation toward RhB under visible-light

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