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Advanced filters: Author: Ze Yu Cen Clear advanced filters

Metabolism fluctuation coupling can track the progression of dementia and describe MST1 gene-related pathology

Sheng et al. characterize features associated with neuroinflammation-related genes and cognitive resilience using a neuroimaging biomarker. The pathological effect of the MST1 gene on cognitive resilience is mediated by the mismatch between metabolic fluctuation coupling in the limbic orbital frontal cortex and amyloid protein deposition.

Jinhua Sheng
Ze Yang
Luyun Wang
ResearchOpen Access12 Jan 2026
Communications Medicine

Volume: 6, P: 1-13
The PP2CH- and PBL27-mediated phosphorylation switch of aluminium ion receptor PSKR1/ALR1 controls plant aluminum sensing ability

This study reveals a regulation mechanism of the ALR1 aluminium receptor involving phosphorylation switching by PP2C phosphatases and PBL27 kinase. This mechanism modulates ALR1–BAK1 complex formation, thereby controlling plant aluminium sensing and resistance.

Chen Xu
Ke Ke Gao
Zhong Jie Ding
Research11 Apr 2025
Nature Plants

Volume: 11, P: 1074-1088
A live-cell image-based machine learning strategy for reducing variability in PSC differentiation systems

Xiaochun Yang
Daichao Chen
Yang Zhao
ResearchOpen Access06 Jun 2023
Cell Discovery

Volume: 9, P: 1-26

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