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Showing 1–6 of 6 results

Advanced filters: Author: Zhao-Qian Pan Clear advanced filters

Nucleophagy is promoted by two autophagy receptors and inhibited by chromatin-nuclear envelope tethering in fission yeast

The authors identify Npr1 as a nucleophagy receptor in fission yeast that acts redundantly with Epr1 to degrade nuclear components. Tethering chromatin to the inner nuclear membrane blocks nucleophagy, suggesting a genome protection mechanism.

Zhu-Hui Ma
Zhao-Qian Pan
Li-Lin Du
ResearchOpen Access31 Mar 2026
Nature Communications

P: 1-18
Structural mechanism of protein recognition by the FW domain of autophagy receptor Nbr1

Nbr1 recognizes cargos in selective autophagy. Here, authors show filamentous yeast Nbr1 binds Ams1 via an FW domain, and the cryo-EM structure reveals that Nbr1 recognizes the N-terminal di-glycine and tetrameric assembly of Ams1.

Jianxiu Zhang
Ying-Ying Wang
Keqiong Ye
ResearchOpen Access25 Jun 2022
Nature Communications

Volume: 13, P: 1-11
Association of positively selected eIF3a polymorphisms with toxicity of platinum-based chemotherapy in NSCLC patients

Ji-ye Yin
Xiang-guang Meng
Zhao-qian Liu
Research03 Mar 2015
Acta Pharmacologica Sinica

Volume: 36, P: 375-384
CHIT1-positive microglia drive motor neuron ageing in the primate spinal cord

Motor neuron senescence and neuroinflammation with microglial hyperactivation are intertwined hallmarks of spinal cord ageing.

Shuhui Sun
Jiaming Li
Guang-Hui Liu
Research31 Oct 2023
Nature

Volume: 624, P: 611-620
Marcks overexpression in retinal ganglion cells promotes optic nerve regeneration

Xue-Qi Peng
Yan-Zhong Li
Chang-Mei Liu
ResearchOpen Access18 Dec 2024
Cell Death & Disease

Volume: 15, P: 1-11
Genetic Polymorphisms and Platinum-based Chemotherapy Treatment Outcomes in Patients with Non-Small Cell Lung Cancer: A Genetic Epidemiology Study Based Meta-analysis

Li-Ming Tan
Cheng-Feng Qiu
Zhao-Qian Liu
ResearchOpen Access17 Jul 2017
Scientific Reports

Volume: 7, P: 1-19