Interleukin 17 (IL-17)-producing helper T cells (TH-17 cells) are associated with the pathogenesis of multiple sclerosis. Pei and colleagues have now identified a TH-17 cell–associated microRNA, miR-326, whose expression correlates with disease severity in patients with multiple sclerosis and mice with experimental autoimmune encephalomyelitis.
- Changsheng Du
- Chang Liu
- Gang Pei