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Showing 1–6 of 6 results

Advanced filters: Author: Zicong Xie Clear advanced filters

PRDX1 promotes testosterone synthesis and attenuates aging via redox regulation of ATG4B to modulate lipophagy

PRDX1 enhances lipophagy and testosterone production by regulating ATG4B. PRDX1 inactivation causes premature testicular aging and aggravates LOH syndromes. Ebselen may be applied to treat male aging-related issues.

Hanbin Zhang
Ke Ma
Zhenguo Chen
ResearchOpen Access19 Nov 2025
Nature Communications

Volume: 16, P: 1-22
Stereoconvergent reduction of alkenes using a repurposed iron-based dioxygenase

A repurposed non-haem, iron-based dioxygenase enables the stereoconvergent reduction of alkenes with excellent selectivity. Mechanistic studies support an iron hydride pathway and reveal the molecular mechanism of stereoconvergence.

Zicong Wan
Xuan Zhang
Pengfei Ji
Research14 Apr 2025
Nature Synthesis

Volume: 4, P: 976-986
PCM1 orchestrates centrosomal and flagellar protein transport to promote sperm maturation

PCM1 governs centrosome remodeling by directing protein transport to promote sperm maturation. Its dysfunction impairs embryo development and causes infertility, highlighting the important role of centrosomal protein in reproduction.

Zicong Huang
Runduan Yi
Zhenguo Chen
ResearchOpen Access07 Jun 2025
Communications Biology

Volume: 8, P: 1-16
Optimization of a CRISPR/Cas9-mediated Knock-in Strategy at the Porcine Rosa26 Locus in Porcine Foetal Fibroblasts

Zicong Xie
Daxin Pang
Xiaochun Tang
ResearchOpen Access08 Jun 2017
Scientific Reports

Volume: 7, P: 1-12
Generation and characterization of stable pig pregastrulation epiblast stem cell lines

Minglei Zhi
Jinying Zhang
Jianyong Han
ResearchOpen Access30 Nov 2021
Cell Research

Volume: 32, P: 383-400
Efficient Generation of Myostatin Mutations in Pigs Using the CRISPR/Cas9 System

Kankan Wang
Hongsheng Ouyang
Daxin Pang
ResearchOpen Access13 Nov 2015
Scientific Reports

Volume: 5, P: 1-11