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Showing 1–25 of 25 results
Advanced filters: Author: Ziyad Al-Aly Clear advanced filters

  • An atlas of the associations between the use of GLP-1 receptor agonists (GLP-1RAs) and 175 health outcomes reports the effectiveness and risks of GLP-1RAs compared with other antihyperglycemic medications, such as sulfonylureas, DPP4 inhibitors and SGLT2 inhibitors.

    • Yan Xie
    • Taeyoung Choi
    • Ziyad Al-Aly
    Research
    Nature Medicine
    Volume: 31, P: 951-962

  • This study shows evidence of different heat risks between people with and without disabilities and by type of disability, cause of admissions, demographic characteristics, and residential population density among people with disabilities.

    • Jinah Park
    • Ayoung Kim
    • Whanhee Lee
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-9

  • Geospatial estimates of the prevalence of anemia in women of reproductive age across 82 low-income and middle-income countries reveals considerable heterogeneity and inequality at national and subnational levels, with few countries on track to meet the WHO Global Nutrition Targets by 2030.

    • Damaris Kinyoki
    • Aaron E. Osgood-Zimmerman
    • Simon I. Hay
    ResearchOpen Access
    Nature Medicine
    Volume: 27, P: 1761-1782

  • Analyses from the US Department of Veterans Affairs databases reported residual elevated risk and health burden of long COVID at 3 years in hospitalized individuals after SARS-CoV-2 infection.

    • Miao Cai
    • Yan Xie
    • Ziyad Al-Aly
    ResearchOpen Access
    Nature Medicine
    Volume: 30, P: 1564-1573

  • SARS-CoV-2 infection can lead to varied post-acute symptoms in the lungs and other organs, including the gastrointestinal system. Here the authors estimate the risks and 1-year burdens of a set of pre-specified incident gastrointestinal outcomes following SARS-CoV-2 infection in an electronic health care record-based cohort study.

    • Evan Xu
    • Yan Xie
    • Ziyad Al-Aly
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-10

  • Analysis of data from the US Department of Veterans Affairs showed that 2 years after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, risk for most postacute sequelae remained elevated in people who were hospitalized with COVID-19 but was attenuated in nonhospitalized individuals.

    • Benjamin Bowe
    • Yan Xie
    • Ziyad Al-Aly
    ResearchOpen Access
    Nature Medicine
    Volume: 29, P: 2347-2357

  • Individuals with COVID-19 are at an increased risk for an array of neurologic disorders at 12 months, even in those who were not hospitalized during the acute phase of the infection.

    • Evan Xu
    • Yan Xie
    • Ziyad Al-Aly
    ResearchOpen Access
    Nature Medicine
    Volume: 28, P: 2406-2415

  • A new analysis using US Department of Veterans Affairs databases showed that reinfection is associated with increased risk of all-cause mortality, hospitalization and a wide range of long COVID complications in individuals who have had SARS-CoV-2 compared to those with no reinfection.

    • Benjamin Bowe
    • Yan Xie
    • Ziyad Al-Aly
    ResearchOpen Access
    Nature Medicine
    Volume: 28, P: 2398-2405

  • A new analysis using the US Department of Veterans Affairs national healthcare databases demonstrates that Long COVID can occur after breakthrough SARS-CoV-2 infection; however, the risk of death attributable to COVID and incidence of post-acute sequelae were substantially reduced (but not fully eliminated) compared to unvaccinated individuals.

    • Ziyad Al-Aly
    • Benjamin Bowe
    • Yan Xie
    ResearchOpen Access
    Nature Medicine
    Volume: 28, P: 1461-1467

  • Healthcare data from the US Department of Veterans Affairs are used to characterize the six-month incident sequelae of individuals who survive for at least thirty days after developing COVID-19.

    • Ziyad Al-Aly
    • Yan Xie
    • Benjamin Bowe
    Research
    Nature
    Volume: 594, P: 259-264

  • Post-acute sequelae of COVID-19 (PASC, or ‘Long COVID’) has caused concern but the burden and risk factors are not well understood. Here, the authors use US electronic health record data and estimate an overall burden of PASC of ~7% at six months, with variation by severity of acute infection, baseline health status and demographics.

    • Yan Xie
    • Benjamin Bowe
    • Ziyad Al-Aly
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12

  • Individuals with COVID-19 are at increased long-term risk for a wide range of cardiovascular disorders, even for individuals who were not hospitalized during the acute phase of the infection.

    • Yan Xie
    • Evan Xu
    • Ziyad Al-Aly
    ResearchOpen Access
    Nature Medicine
    Volume: 28, P: 583-590

  • Long COVID, which refers to post-acute and chronic sequelae of SARS-CoV-2 infection, can affect nearly every organ system and all demographic groups. The high and growing toll of long COVID calls for an urgent need to understand how to prevent and treat it. Governments and health systems must address the care needs of people with long COVID.

    • Ziyad Al-Aly
    • Anupam Agarwal
    • Valerie A. Luyckx
    Comments & Opinion
    Nature Reviews Nephrology
    Volume: 19, P: 1-2

  • Fine-scale geospatial mapping of overweight and wasting (two components of the double burden of malnutrition) in 105 LMICs shows that overweight has increased from 5.2% in 2000 to 6.0% in children under 5 in 2017. Although overall wasting decreased over the same period, most countries are not on track to meet the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025.

    • Damaris K. Kinyoki
    • Jennifer M. Ross
    • Simon I. Hay
    ResearchOpen Access
    Nature Medicine
    Volume: 26, P: 750-759

  • Analyses of the proportions of individuals who have completed key levels of schooling across all low- and middle-income countries from 2000 to 2017 reveal inequalities across countries as well as within populations.

    • Nicholas Graetz
    • Lauren Woyczynski
    • Simon I. Hay
    ResearchOpen Access
    Nature
    Volume: 577, P: 235-238

  • In this disease mapping study, the authors estimate disability-adjusted life year rates for three of the major causes of mortality for children under five 43 countries in sub-Saharan Africa. They identify significant heterogeneity at the subnational level, highlighting the need for a targeted intervention approach.

    • Robert C. Reiner Jr.
    • Catherine A. Welgan
    • Simon I. Hay
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-14

  • This Review outlines the current state of scientific evidence on long COVID, discusses its impacts on patients, health systems, economies and global health metrics, and proposes a forward-looking research and policy roadmap.

    • Ziyad Al-Aly
    • Hannah Davis
    • Eric J. Topol
    Reviews
    Nature Medicine
    Volume: 30, P: 2148-2164

  • Choi et al. report on the effectiveness of SGLT2 inhibitors in reducing risk of major adverse cardiovascular events (MACE) and major adverse kidney events (MAKE) in people with SARS-CoV-2 infection. They show that compared to other antihyperglycemics, SGLT2 inhibitors reduce the risk of both MACE and MAKE after SARS-CoV-2 infection.

    • Taeyoung Choi
    • Yan Xie
    • Ziyad Al-Aly
    ResearchOpen Access
    Communications Medicine
    Volume: 4, P: 1-8

  • Working towards sustainable development is essential to tackle the rise in the global burden of non-communicable diseases, including kidney disease. Five years after the Sustainable Development Goal agenda was set, this Review examines the progress thus far, highlighting future challenges and opportunities, and explores the implications for kidney disease.

    • Valerie A. Luyckx
    • Ziyad Al-Aly
    • John Stanifer
    Reviews
    Nature Reviews Nephrology
    Volume: 17, P: 15-32