Cover Gallery 2021
Year 2021, Volume 6
December
Natural killer cell-derived exosomal miR-1249-3p attenuates insulin resistance and inflammation in mouse models of type 2 diabetesYing Wang, Mengwei Li, Lin Chen, Huan Bian, Xiangying Chen, Huilin Zheng, Peiwei Yang, Quan Chen & Hanmei Xu
November
Mesenchymal stem cell-derived small extracellular vesicles mitigate oxidative stress-induced senescence in endothelial cells via regulation of miR-146a/SrcXian Xiao, Meiqian Xu, Hongliang Yu, Liping Wang, Xiaoxia Li, Janusz Rak, Shihua Wang & Robert Chunhua Zhao
October
CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta, alpha, beta, and gammaJiejie Geng, Liang Chen, Yufeng Yuan, Ke Wang, Youchun Wang, Chuan Qin, Guizhen Wu, Ruo Chen, Zheng Zhang, Ding Wei, Peng Du, Jun Zhang, Peng Lin, Kui Zhang, Yongqiang Deng, Ke Xu, Jiangning Liu, Xiuxuan Sun, Ting Guo, Xu Yang, Jiao Wu, Jianli Jiang, Ling Li, Kun Zhang, Zhe Wang, Jing Zhang, Qingguo Yan, Hua Zhu, Zhaohui Zheng, Jinlin Miao, Xianghui Fu, Fengfan Yang, Xiaochun Chen, Hao Tang, Yang Zhang, Ying Shi, Yumeng Zhu, Zhuo Pei, Fei Huo, Xue Liang, Yatao Wang, Qingyi Wang, Wen Xie, Yirong Li, Mingyan Shi, Huijie Bian, Ping Zhu & Zhi-Nan Chen
September
ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker
Yuning Chen, Ya-Nan Zhang, Renhong Yan, Guifeng Wang, Yuanyuan Zhang, Zhe-Rui Zhang, Yaning Li, Jianxia Ou, Wendi Chu, Zhijuan Liang, Yongmei Wang, Yi-Li Chen, Ganjun Chen, Qi Wang, Qiang Zhou, Bo Zhang & Chunhe Wang
August
A novel dephosphorylation targeting chimera selectively promoting tau removal in tauopathies
Jie Zheng, Na Tian, Fei Liu, Yidian Zhang, Jingfen Su, Yang Gao, Mingmin Deng, Linyu Wei, Jingwang Ye, Honglian Li & Jian-Zhi Wang
July
CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in miceLu Gan, Demin Liu, Jing Liu, Erya Chen, Chan Chen, Lian Liu, Hang Hu, Xiaohui Guan, Wen Ma, Yanzi Zhang, Yarong He, Bofu Liu, Songling Tang, Wei Jiang, Jianxin Xue & Hongbo Xin
June
UBQLN1 mediates sorafenib resistance through regulating mitochondrial biogenesis and ROS homeostasis by targeting PGC1β in hepatocellular carcinomaJunjie Xu, Lin Ji, Yeling Ruan, Zhe Wan, Zhongjie Lin, Shunjie Xia, Liye Tao, Junhao Zheng, Liuxin Cai, Yifan Wang, Xiao Liang & Xiujun Cai
May
RNA-induced liquid phase separation of SARS-CoV-2 nucleocapsid protein facilitates NF-κB hyper-activation and inflammationYaoxing Wu, Ling Ma, Sihui Cai, Zhen Zhuang, Zhiyao Zhao, Shouheng Jin, Weihong Xie, Lingli Zhou, Lei Zhang, Jincun Zhao & Jun Cui
April
Targeting Erbin in B cells for therapy of lung metastasis of colorectal cancer
Tong Shen, Jing-Lin Liu, Chu-Yi Wang, Youlutuziayi Rixiati, Shi Li, Ling-Dong Cai, Yuan-Yuan Zhao & Jian-Ming Li
March
Therapeutic potential of C1632 by inhibition of SARS-CoV-2 replication and viral-induced inflammation through upregulating let-7Chen Xie, Yanlian Chen, Dongling Luo, Zhen Zhuang, Heping Jin, Haoxian Zhou, Xiaocui Li, Haijun Lin, Xiaohui Zheng, Jing Zhang, Peihui Wang, Jincun Zhao, Yong Zhao & Hui Huang
February
Personalized neoantigen pulsed dendritic cell vaccine for advanced lung cancer
Zhenyu Ding, Qing Li, Rui Zhang, Li Xie, Yang Shu, Song Gao, Peipei Wang, Xiaoqing Su, Yun Qin, Yuelan Wang, Juemin Fang, Zhongzheng Zhu, Xuyang Xia, Guochao Wei, Hui Wang, Hong Qian, Xianling Guo, Zhibo Gao, Yu Wang, Yuquan Wei, Qing Xu, Heng Xu & Li Yang
January
CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1
Junjie Xu, Lin Ji, Yuelong Liang, Zhe Wan, Wei Zheng, Xiaomin Song, Kirill Gorshkov, Qiming Sun, Hui Lin, Xueyong Zheng, Jiang Chen, Ren-an Jin, Xiao Liang & Xiujun Cai
