Cover Gallery 2024

Year 2024, Volume 9

December

Neoadjuvant oncolytic virus orienx010 and toripalimab in resectable acral melanoma: a phase Ib trial

Jiayong Liu, Xuan Wang, Zhongwu Li, Shunyu Gao, Lili Mao, Jie Dai, Caili Li, Chuanliang Cui, Zhihong Chi, Xinan Sheng, Yumei Lai, Zhichao Tan, Bin Lian, Bixia Tang, Xieqiao Yan, Siming Li, Li Zhou, Xiaoting Wei, Juan Li, Jun Guo & Lu Si

November

Perioperative sintilimab and neoadjuvant anlotinib plus chemotherapy for resectable non-small-cell lung cancer: a multicentre, open-label, single-arm, phase 2 trial (TD-NeoFOUR trial)

Hongtao Duan, Changjian Shao, Zhilin Luo, Tianhu Wang, Liping Tong, Honggang Liu, Xin Yao, Jie Lei, Jinbo Zhao, Yuan Gao, Tao Jiang & Xiaolong Yan

October

Characterization of ferroptosis-triggered pyroptotic signaling in heart failure

Xukun Bi, Xiaotian Wu, Jiaqi Chen, Xiaoting Li, Yangjun Lin, Yingying Yu, Xuexian Fang, Xihao Cheng, Zhaoxian Cai, Tingting Jin, Shuxian Han, Meihui Wang, Peidong Han, Junxia Min, Guosheng Fu & Fudi Wang

September

Potassium voltage-gated channel subfamily H member 2 (KCNH2) is a promising target for incretin secretagogue therapies

Ying-Chao Yuan, Hao Wang, Ze-Ju Jiang, Chang Liu, Qi Li, Si-Rui Zhou & Jin-Kui Yang

August

Bacterial persisters: molecular mechanisms and therapeutic development

Hongxia Niu, Jiaying Gu & Ying Zhang

July

Real-world effectiveness of early insulin therapy on the incidence of cardiovascular events in newly diagnosed type 2 diabetes

Sihui Luo, Xueying Zheng, Wei Bao, Sheng Nie, Yu Ding, Tong Yue, Yilun Zhou, Ying Hu, Hua Li, Qiongqiong Yang, Qijun Wan, Bicheng Liu, Hong Xu, Guisen Li, Gang Xu, Chunbo Chen, Huafeng Liu, Yongjun Shi, Yan Zha, Yaozhong Kong, Guobin Su, Ying Tang, Mengchun Gong, Linong Ji, Fan Fan Hou & Jianping Weng

June

Targeting BCL9/BCL9L enhances antigen presentation by promoting conventional type 1 dendritic cell (cDC1) activation and tumor infiltration

Fenglian He, Zhongen Wu, Chenglong Liu, Yuanyuan Zhu, Yan Zhou, Enming Tian, Rina Rosin-Arbesfeld, Dehua Yang, Ming-Wei Wang & Di Zhu

May

FGF7 enhances the expression of ACE2 in human islet organoids aggravating SARS-CoV-2 infection

Hao Meng, Zhiying Liao, Yanting Ji, Dong Wang, Yang Han, Chaolin Huang, Xujuan Hu, Jingyi Chen, Hengrui Zhang, Zonghong Li, Changliang Wang, Hui Sun, Jiaqi Sun, Lihua Chen, Jiaxiang Yin, Jincun Zhao, Tao Xu & Huisheng Liu

April

Rapid development of double-hit mRNA antibody cocktail against orthopoxviruses

Hang Chi, Suo-Qun Zhao, Ru-Yi Chen, Xing-Xing Suo, Rong-Rong Zhang, Wen-Hui Yang, Dong-Sheng Zhou, Min Fang, Bo Ying, Yong-Qiang Deng & Cheng-Feng Qin