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Irritable bowel syndrome is a condition that affects the digestive system, with a mixed group of recurrent symptoms that can include abdominal pain, altered defecation and bloating. Irritable bowel syndrome is considered a functional bowel disorder with no known organic cause.
Irritable bowel syndrome (IBS) is a complex and chronic gastrointestinal disorder associated with dysregulation of the gut-brain axis. Here, the authors develop an engineered microalgae that can address the pharmacokinetic complications of IBS and achieve the treatment of multi-organ symptoms.
This Perspective discusses misconceptions and controversies in the clinical management of irritable bowel syndrome (IBS), including diagnosis, testing and treatment, among others. Areas in which issues have been resolved and those that require further research and clarification are highlighted.
Inflammatory bowel disease remains a global health challenge, despite advances in treatment and understanding of disease biology. In this issue, we focus on the most pressing priorities in inflammatory bowel disease research and care.
Bathroom ban legislation is increasing throughout the United States, and little is known about the effect on transgender and gender-nonconforming individuals with chronic gastrointestinal conditions. Efforts should be made to raise awareness and address the knowledge gaps.
Key studies published in 2022 further established the importance of alterations in the gut microenvironment and interactions with the enteric and central nervous systems in symptom generation in irritable bowel syndrome and suggested novel and clinically accessible therapeutic approaches for this large group of patients.
