Neonatal sepsis articles from across Nature Portfolio

Fortmann and Dappen et al., investigate whether repeated neonatal elevations of C-reactive protein predict long-term lung health in very preterm infants. They report that recurrent inflammation correlates with poorer lung function and reduced exercise capacity at school age, underscoring its lasting impact on respiratory development.

Here, via ITS2 gene profiling of rectal samples from 102 healthy Gambian infants, the authors show that intrapartum azithromycin has an overall mild effect on gut mycobiota development but associates with increased abundance of C. orthopsilosis in the wet season.

CD4⁺T cells in newborn babies show increased production of CXCL8, which could be important for defence against infections.

Neonatal erythroid cells actively suppress immune responses against microbes.